A tibial plateau three-column anatomical bone plate belongs to the technical field of orthopedic surgical instruments and is used for fixing the three-column anatomical fracture of the tibial plateau. The present invention can simultaneously fix the fracture blocks of the lateral column and the medial column through the medial and lateral column fixing plate at the top of the bone plate, and at the same time, the posterior column fixing plate can fix the posteromedial column of the medial tibial platform, the posterior column of the lateral tibial platform, and the lateral tibia The posterior column fracture fragments of the posterior lateral column of the tibial plateau are fixed, so that the lateral column, medial column and posterior column of the tibial plateau can be simultaneously fixed by using a single bone plate. The present invention creatively proposes a layered fixation structure, a breakthrough and a new fixation mode of "multi-plane, three-dimensional fixation", and skillfully solves the clinical key and difficult problem of the three-column fracture of the tibial plateau, greatly reducing the operation time. Trauma, operation time, intraoperative and postoperative complication rates are conducive to early fracture healing and early functional exercise, so as to achieve better therapeutic effect.