The invention relates to a cake forming method of high-purity alumina powder, belongs to the technical field of chemical machining forming methods, and in particular to an alumina cake forming method. The cake forming method comprises the steps of preforming, vacuum sealing, isostatic cool pressing, high-temperature sintering and the like. According to the invention, a mould made of a PP or tetra fluorine material is adopted, pollution caused by high-purity alumina by the traditional steel mould is avoided, a preformed cake obtained by through low-pressure pressing can ensure that the cake in the later-stage isostatic cool pressing does not easily deform like the original organic mould due to a certain strength, thus the cake with uniform material and enough density is obtained. The cake subjected to the isostatic cool pressing has unchangeable purity after being sintered, and has uniform shape and size and density of commonly reaching 3.0-3.7g/cm<3>. The loading quantity during producing and loading of a downstream manufacturer of sapphire can be effectively increased.