88results about How to "Rapid characterization" patented technology

Methods, systems and devices are described for rapid characterization and screening of liquid samples to determine properties (e.g., particle size, particle size distribution, molar mass and / or molar mass distribution) thereof with static light scattering and / or dynamic light scattering. The liquid samples can be solutions, emulsions, suspensions or dispersions. One method, includes providing a vessel containing a liquid sample having an exposed surface that defines a gas-liquid sample interface, and analyzing the sample by light scattering methods that include transmitting light through the gas-liquid sample interface into the sample, and detecting light scattered from the sample or from a component thereof. Additional methods are directed to characterizing a plurality of liquid samples or components thereof. The methods, systems, and devices have applications in high-throughput screening, and particularly, in combinatorial materials research and in industrial process control.

Systems and methods are disclosed for vehicle motion planning where a sensor, such as a ladar system, is used to detect threatening or anomalous conditions within the sensor's field of view so that priority warning data about such conditions can be inserted at low latency into the motion planning loop of a motion planning computer system for the vehicle. The ladar system can perform compressive sensing to target the field of view with a plurality of ladar pulses.

Method and apparatus for field ion mobility spectrometry for identification of chemical compounds in a sample by trajectory of sample ions in a transverse electric field.

A ladar system can estimate intra-frame motion for an object within a field of view of the ladar system using a tight cluster of ladar pulses. For example, ladar pulses in a cluster can be spaced apart but overlapping with at least one of the other ladar pulses in that cluster at a specified distance in the field of view. A ladar receiver can then process the reflections from the cluster to computer intra-frame motion data, such as intra-frame velocity and intra-frame acceleration for an object.

A rapid throughput method for the preparation, analysis or both of libraries of material samples is provided. According to the method, a plurality of samples is provided. The plurality of samples is then formed into a plurality of films. Thereafter, the plurality of films is plastically deformed. Preferably, the plurality of films is deformed into a configuration appropriate for testing of properties or characteristics of the samples.

The present invention is directed to a method for separating, characterizing and / or identifying microorganisms in a test sample. The method of the invention comprises an optional lysis step for lysing non-microorganism cells that may be present in a test sample, followed by a subsequent separation step. The method may be useful for the separation, characterization and / or identification of microorganisms from complex samples such as blood-containing culture media. The invention further provides for spectroscopic interrogation of the separated microorganism sample to produce measurements of the microorganism and characterizing and / or identifying the microorganism in the sample using said spectroscopic measurements.

An automated method for testing audio signal quality of cell phone transmissions provides a Mean Opinion Score (MOS) output using inexpensive test components. The test system uses a server computer to eliminate the need for expensive faders used in a bench test system. The server computer manipulates data packets from the reference media file to simulate impairments, including losses, errors, noise and jitter, at a much lower cost than using actual faders. Transmission through two separate radio access networks RANs is provided to simulate two parties communicating using separate mobile devices (an end-to-end test solution) with a single cell phone.

The present invention is directed to a method for separating, characterizing and / or identifying microorganisms in a test sample. The method of the invention comprises an optional lysis step for lysing non-microorganism cells that may be present in a test sample, followed by a subsequent separation step. The method may be useful for the separation, characterization and / or identification of microorganisms from complex samples such as blood-containing culture media. The invention further provides for Raman spectroscopic interrogation of the separated microorganism sample to produce measurements of the microorganism and characterizing and / or identifying the microorganism in the sample using said Raman spectroscopic measurements.

What is disclosed is a novel system and method for quickly characterizing a reflectance sensing device without measuring the full set of characterization color patch training samples currently used in manufacturing and characterizing individual sensors. In accordance with the teachings hereof, measurements of training samples taken with a previously manufactured ‘fleet master’ sensing device are adapted, in a manner more fully disclosed herein, based upon knowledge of the wavelengths of the illuminators used for both the subject and fleet master sensors, as well as spectral reflectance response of the training samples as measured by a reference spectrophotometer device. Utilizing the adapted measurements of the fleet master device, a reconstruction matrix can be quickly constructed for the subject sensor. The present system and method provides reasonably good accuracy using pre-existing measurement data. This results in manufacturing cost savings on a per-sensor basis.

The present invention is directed to a method for separating, characterizing and / or identifying microorganisms in a test sample. The method of the invention comprises an optional lysis step for lysing non-microorganism cells that may be present in a test sample, followed by a subsequent separation step. The method may be useful for the separation, characterization and / or identification of microorganisms from complex samples such as blood-containing culture media. The invention further provides for spectroscopic interrogation of the separated microorganism sample to produce measurements of the microorganism and characterizing and / or identifying the microorganism in the sample using said spectroscopic measurements.

An automated method for testing audio signal quality of cell phone transmissions provides a Mean Opinion Score (MOS) output using inexpensive test components. The test system uses a server computer to eliminate the need for expensive faders used in a bench test system. The server computer manipulates data packets from the reference media file to simulate impairments, including losses, errors, noise and jitter, at a much lower cost than using actual faders. Transmission through two separate radio access networks RANs is provided to simulate two parties communicating using separate mobile devices (an end-to-end test solution) with a single cell phone.

This invention provides a device and methods for the rapid detection and / or diagnosis and / or characterization of one or more allergies (e.g., causes IgE mediated allergic reaction (immediate hypersensitvity) in a mammal (e.g., a human or a non-human mammal). In certain embodiments, the device comprises a microcantilever array where different cantilevers comprising the array bear different antigens. Binding of IgE to the antigen on a cantilever causes bending of the cantilever which can be readily detected.

The present invention relate to methods and compositions for simultaneously analyzing multiple different polynucleotides of a nucleic acid sample. The subject methods and compositions may also be applied to analyze or identify single polynucleotide; however, the subject methods and compositions are particularly useful for analyzing large diverse populations of polynucleotides. Methods of the invention involve hybridizing guide oligonucleotides to target polynucleotides for analysis, subsequently digesting double-stranded or partially double-stranded guide oligonucleotide intermediates, and isolating and analyzing digested part. The guide oligonucleotide is marked in identifier sequence and constant region so as to facilitate the simultaneous testing of multiple target polynucleotides. The identity or expression of a particular polynucleotide of interest may be ascertained by producing and quantifying a short identifier sequence derived from combining guide oligonucleotides and target polynucleotides.

A system and a method of detecting and characterizing a bacterial colony are presented in which the results are determined within about 48 hours. The bacterial colony is disposed on a substrate and placed between a laser and detector. Light from the laser impinges upon and is scattered by the bacterial colony. The forward scattered light is detected by an optical detector. The signal from the optical detector is analyzed by an analyzer and displayed or supplied to a storage medium for review. As different strains of bacteria possess unique forward scattering fingerprints, the particular strain may be identified.

Disclosed herein are examples of ladar systems and methods where data about a plurality of ladar returns from prior ladar pulse shots gets stored in a spatial index that associates ladar return data with corresponding locations in a coordinate space to which the ladar return data pertain. This spatial index can then be accessed by a processor to retrieve ladar return data for locations in the coordinate space that are near a range point to be targeted by the ladar system with a new ladar pulse shot. This nearby prior ladar return data can then be analyzed by the ladar system to help adapt a shot selection for use by the ladar system with respect to new ladar pulse shots.

A system and a method of detecting and characterizing a bacterial colony are presented in which the results are determined within about 48 hours. The bacterial colony is disposed on a substrate and placed between a laser and detector. Light from the laser impinges upon and is scattered by the bacterial colony. The forward scattered light is detected by an optical detector. The signal from the optical detector is analyzed by an analyzer and displayed or supplied to a storage medium for review. As different strains of bacteria possess unique forward scattering fingerprints, the particular strain may be identified.

The present invention is directed to a method for separating, characterizing and / or identifying microorganisms in a test sample. The method of the invention comprises an optional lysis step for lysing non-microorganism cells that may be present in a test sample, followed by a subsequent separation step. The method may be useful for the separation, characterization and / or identification of microorganisms from complex samples such as blood-containing culture media. The invention further provides for the use of one or more identifier agents and interrogating the microorganism sample and / or said one or more identifier agents to produce measurements which characterizing and / or identifying the microorganism based on the produced measurements and / or the presence or absence of the identifier agent or a metabolized form of the identifier agent in the microorganism sample.

The present invention relates to methods and systems for scanning, detecting, and monitoring microorganisms on solid or semi-solid media using intrinsic fluorescence (IF) measurements. The methods are further directed to detection, characterization and / or identification of microorganisms on a solid or semi-solid media using intrinsic fluorescence (IF) measurements that are characteristic of said microorganisms.

The invention relates to a method of quickly representing chemical components in a sample based on UPLC-QTOF. Information of the chemical components in the sample is acquired through non-target metabolic profiling analysis of UPLC-QTOF of the sample. The method specifically comprises chromatographic peak extraction, high precision mass spectrometric representation and clustering of ionic fragments of a same substance. The method specifically comprises the following steps: firstly, transforming high resolution mass spectrum data in UPLC-QTOF into a low resolution mass spectrum and extracting chromatographic signals under m / z; correcting a baseline drift problem in the chromatographic signal by means of iterative optimization of local minimum; after baseline correction, optimizing by using a Gaussian smooth ridge line to obtain the positions of the chromatographic peaks in the chromatographic signal; extracting corresponding high-precision mass spectra to represent the chromatographic peaks according to the positions of the chromatographic peaks, wherein each chromatographic peak can correspond to the fragment ionic signal of a compound in a mass spectrum ionic source; and finally, clustering the cracked fragments in the source corresponding to same substance and finally quickly representing the chemical components in the sample.

Systems, methods, and apparatus for determining whether a culture in a vessel contains a plurality of microorganisms are provided. A normalization relative value is calculated for each respective measurement of a biological state of the culture between (i) the respective measurement and (ii) an initial biological state. For each fixed interval of time points, a derivative of the normalization relative values in the interval of time points is calculated, thereby forming a plurality of rate transformation values. For each set of rate transformation values in the plurality of rate transformation values, a measure of central tendency of the values in the set is computed, thereby forming a plurality of average relative transformation values. A determination whether the culture contains the microorganisms is made based on whether any calculated average relative transformation value exceeds a first threshold or whether an extent of growth exhibited by the culture exceeds a second threshold.

The invention discloses a method for detecting the heat dissipating property of a metal heat dissipation device and a testing device thereof. The method is characterized in that a detected heat dissipation device is arranged in a cavity, a heated end of the detected heat dissipation device is attached with a steady temperature-controllable heat source to raise the temperature of the heat dissipation device, an airflow cooling heat-dissipating device with controllable temperature and adjustable flow rate is arranged at the heat dissipation part of the heat dissipation device, and the temperature of airflows flowing through the heat dissipation device and heated by the heat dissipation device is recorded; when the heat dissipation device is heated and cooled stably, the temperature of the stably heated airflows represents the comprehensive heat dissipation property of the heat dissipation device, that is, the higher the stable temperature of the heated air flows is, the better of the comprehensive heat dissipation property of the heat dissipation device is under the constant heat source with the same temperature and the same cooling condition, therefore, the comprehensive heat dissipation property of the heat dissipation device is represented and estimated; according to the method, the complex heat dissipating process and the contribution of the physical property parameters of the heat dissipating metal and the structural characteristics of the heat dissipation device to the heat dissipating property of the heat dissipation device are comprehensively considered.

Media and kits are disclosed for use in processes requiring microbial culture. More specifically, the invention provides carrageenan-stabilized agar-based microbial culture media and kits constructed using the media. The media and kits of the invention may allow the construction of kits with increased shelf stability and useful life. Further, the media and kits of the invention may be used in kits and methods useful in the manual determination of the type of infection present in a specimen in periods of about 24 hours. The stabilized culture media of the invention are useful in a broad variety of applications. In an embodiment, the media contains both an agar medium and iota carrageenan.

A provided measure method for combined distribution of nanometer particle concentration and geometrical characteristic quantity comprises providing a spectral measurement system; calibrating the spectral measurement system; calibrating the spectral measurement system by utilizing a standard substance; replacing a standard nanoparticle in a measurement sample cell by a to-be measured nanoparticle, and putting a dispersing solvent of the to-be measured nanoparticle into a reference sample cell; then emptying the reference sample cell, and respectively measuring the to-be measured nanoparticle sample, so as to obtain the relative transmittance, the transmittance and a ratio of 90 DEG diffusion light intensity to reference light intensity; obtaining the 90 DEG diffusion light spectrum of the to-be measured nanoparticle; constructing a geometrical model of the to-be measured nanoparticle, and forming a standard spectral database; creating a reverse problem solving model, solving a reverse problem, and connecting the spectrum obtained through measurement and to-be characterized parameter with the standard spectrum data; and calculating the combined distribution of the nanoparticle concentration and the geometrical characteristic quantity, so as to obtain the to-be characterized parameter.

A method of determining a state of ventricular fibrillation, includes: measuring the rhythm of the heart during ventricular fibrillation for a period of time; creating a lagged phase space reconstruction of the measured rhythm; determining a first value related to the rate of change of the leading edge of the phase space reconstruction over the period of time; and determining the state of ventricular fibrillation by relating the first value to the state of ventricular fibrillation. A defibrillation system includes at least one processor in communication with a sensor to measure heart rhythm and an applicator to apply a defibrillation pulse. The processor is adapted to create a lagged phase space reconstruction of ventricular fibrillation heart rhythm and to determine a first value related to the rate of change of the leading edge of the phase space reconstruction over a period of time.

The invention discloses a testing and correction method of a square resistance in an ohmic contact area for mainly solving the problems of inaccurate calculation and complex calculation process of the square resistance Rshc in the ohmic contact area in the prior art. The realization scheme comprises the steps of manufacturing two groups of similar round ohmic contact testing patterns, wherein each group comprises a round ohmic electrode and two concentric ring-shaped ohmic electrodes; then testing the total resistance of the two groups of the round testing patterns, respectively; and correcting the value of the square resistance Rsh in an active area by utilizing a correction formula so as to further calculate the value of the square resistance Rshc in the ohmic contact area accurately. The correction method of the square resistance in the ohmic contact area has the advantages of simple and easily-manufactured testing patterns, simple calculation and accurate result, and can be used for technology detection and performance evaluation of semiconductor devices.

Characterization of an optical system is quickly and easily obtained in a single acquisition step by obtaining image data within a volume of image space. A reticle and image plane are positioned obliquely with respect to each other such that a reticle having a plurality of feature sets thereon, including periodic patterns or gratings, is imaged in a volume of space, including the depth of focus. Metrology tools are used to analyze the detected or recorded image in the volume of space through the depth of focus in a single step or exposure to determine the imaging characteristics of an optical system. Focus, field curvature, astigmatism, spherical, coma, and / or focal plane deviations can be determined. The present invention is particularly applicable to semiconductor manufacturing and photolithographic techniques used therein, and is able to quickly characterize an optical system in a single exposure with dramatically increased data quality and continuous coverage of the full parameter space. In embodiments, the test reticle is holographically generated by interfering two or more beams of optical radiation. The resulting interference pattern is recorded on a reticle and used for testing the optical system. The geometry of the holographic interference pattern is tightly controlled by the properties of the interfering beams and is therefore more accurate than conventional reticle writing techniques.