35 results about "Biotic component" patented technology

Systems for analyzing biological components are provided. The systems may include a fluidic device and an energy source in communication with the fluidic device. The energy source may supply energy to the fluidic device to form a polymer matrix on or adjacent to a biological component within the fluidic device. Methods of using the systems to analyze biological components are also provided.

Understand the effects of manipulations on biological components. [Solution] The prediction device includes a first acquisition unit that acquires a first dataset including a first set of a first sequence of a first gene involved in a trait and its phenotype, a second acquisition unit that acquires a second sequence, a first setting unit that sets an editing cost for a reference sequence based on the change between each phenotype in the first set and the reference phenotype in the reference sequence, a second setting unit that updates the editing cost, a first generation unit that generates a first list of first sequences included in the second sequence, a second generation unit that generates a second list of first sequences including the second sequence, a first identification unit that identifies a third sequence in the first list that has the smallest effect of genome editing, a second identification unit that identifies a fourth sequence in the second list that has the largest effect of genome editing, and a prediction unit that predicts a new phenotype under the second sequence based on the proportional relationship between the editing distance between different sequences and the change in each of the two sequences, the first dataset, the third sequence, the fourth sequence, and the editing cost.

The invention discloses a compound root humectant for improving the transplanting survival rate of cassava seedlings and a preparation method of the compound root humectant, and relates to the technical field of functional preparations for agricultural planting. Comprising 8-13 parts of a cassava homologous extract, 2-4 parts of trichoderma spore powder, 1-3 parts of an allicin derivative, 6-10 parts of modified konjac glucomannan, 11-17 parts of an intelligent water absorption component and 4-6 parts of a betaine-humic acid chelated nutrition component. Through the specific matching of the cassava homologous extract and the trichoderma spore powder-allicin derivative composite disease prevention component, and in combination with a customization process of low-temperature activation and targeted layered coating, the effectiveness of bioactive components is effectively retained, and the three-layer structure microparticles realize a closed loop of activity retention, precise attachment and step-by-step release, so that the disease prevention effect is improved. The inner-layer biological components play a role in root promotion and disease prevention after transplanting, the middle-layer intelligent water absorption components continuously lock water, and the outer-layer chelating nutrient components are slowly supplied, so that the absorption rule of thin and weak root systems of cassava seedlings is accurately adapted.

The invention relates to the field of agriculture, and discloses a biological organic compound fertilizer and a preparation method thereof, and the biological organic compound fertilizer comprises the following components: 10%-20% of sodium humate; 2%-6% of a seaweed extract; 1%-3% of natural organic acid; 5%-15% of ammonium sulfate; 4%-10% of monoammonium phosphate; 3%-7% of potassium chloride; 2%-5% of nano silicon; 2%-4% of polyvinyl alcohol; 1%-3% of polyacrylic acid; 2%-5% of calcium sulfate; 1%-4% of calcium phosphate; 3%-6% of amino acid; and 2%-4% of trace elements. By combining various organic and biological components such as the sodium humate, the seaweed extract and the microbial agent, the effects of slowly releasing nutrients and promoting crop growth are achieved, and compared with a scheme of singly using a chemical fertilizer or an organic fertilizer in the prior art, the compound fertilizer disclosed by the invention can release the nutrients more enduringly, so that the crop growth is promoted. The side effect of overuse of the chemical fertilizer is avoided.

Provided is a reagent for biological component measurement which is capable of reducing the effects of dobesilic acid. One embodiment of the present invention is a reagent for biological component measurement containing a nitroxyl radical that has a redox-reactive functional group or does not have a functional group.

Disclosed are systems and methods for a bioprinter capable of printing an object having biological components. In some embodiments, the bioprinter includes a modular print bed having a recessed area configured to receive a variable insert and a printer head positioned above the modular print bed. In some embodiments, the printer head has a cartridge for receiving and holding a biomaterial, and an extruder configured to extrude biomaterials from the cartridge onto a portion of the variable insert. The variable insert may include functional elements (e.g., heating, cooling, photocuring) and / or receiving elements (e.g., well plates).

The present invention discloses a method for large-scale extraction of extracellular membrane vesicles (OMV / FGF2) secreted by Escherichia coli that has ampicillin resistance and can secrete bFGF protein after gene editing. The method cultured Escherichia coli in LB liquid containing 100ug / mL ampicillin, and used ultrasonic separation and filtration technology to effectively separate the extracellular membrane vesicles loaded with bFGF protein from Escherichia coli without Escherichia coli cells. The extraction method is simple and easy to operate, and the yield of extracellular membrane vesicles is greatly improved under the premise of retaining most of the effective biological components of bacterial outer membrane vesicles. At the same time, the method effectively removes the live bacterial cells of Escherichia coli, ensures the safety of the body, and greatly reduces the risk of bacteremia or scurvy induced by microorganisms entering the blood. In addition, the OMV / FGF2 extracted by the method was applied to colitis wounds, and it was found that it could significantly promote the healing of colitis wounds.

An optical medium (3) includes a first surface (31) and a second surface (32) on the opposite side from the first surface, and is transparent to excitation light (7). A bioprotective film (4) is provided on the first surface (31) of the optical medium (3) and is transparent to the excitation light (7). The bioprotective film (4) has a sample placement surface (41). An excitation light source (1) emits the excitation light (7). A probe light source (2) emits probe light (9) that progresses through the optical medium (3). The optical medium (3) is also transparent to the probe light (9). The excitation light (7) enters the optical medium (3) from the second surface (32) of the optical medium (3), and progresses through the optical medium (3) and the bioprotective film (4) toward a sample (8) placed on the sample placement surface (41). A light position detector (5) detects the positions of probe light beams (9a, 9b) emitted from the optical medium (3). A calculation device (6) measures the biological component of the sample (8) on the basis of the positions (10a, 10b) of the probe light beams detected by the light position detector (5).

A skid for use in biological component separation includes a housing partially bounding a compartment with a mounting platform, and a loading assembly secured to the housing and in communication with the compartment, the loading assembly including an alignment plate having a top surface with a cavity recessed therein, the cavity in communication with the compartment, a drive rotor rotatably disposed below the alignment plate and at least partially surrounding the cavity and including one or more magnets, a motor coupled to the drive rotor for selectively rotating the drive rotor around the cavity, and a mounting portion including a mounting plate at least partially surrounding the drive rotor and in communication with the compartment, the mounting portion having one or more mounting elements upstanding thereon, the mounting portion being movable between a raised position in which the mounting plate is aligned with the alignment plate and a second lowered position in which the mounting plate is disposed lower than the alignment plate.

The present disclosure relates to a method, apparatus, and computer program for preprocessing input data for predicting growth of children or adolescents. A method of preprocessing height measurement data for growth prediction according to an exemplary embodiment of the present disclosure may include receiving time-series bio-component data of a subject; receiving identification data of the subject, extracting height data from the bio-component data, determining whether there is a decreasing section within a section where the height data is input, and when there is the section where the height data decreases, determining an error in the height data based on a growth stage in which the decreasing section is included.

A system for analyzing biological components in a biological sample, the system comprising a fluid device, the system being configured to perform a process comprising: a) receiving a fluid device, wherein: the fluid device comprises a chamber, a port, and a channel; the chamber, port, and channel are interconnected and fluidically communal; the fluid device is configured to receive a biological sample, the biological sample comprising a plurality of cells, and the biological sample having a flow direction within the fluid device; b) compartmentalizing each cell of at least 10⁵ cells of the plurality of cells, thereby physically separating each cell of the at least 10⁵ cells; c) lyseing at least a portion of the at least 10⁵ cells, thereby releasing mRNA molecules from the at least portion of the at least 10⁵ cells;andd) Capture at least a subset of the mRNA molecules using a variety of capture elements, thereby obtaining captured mRNA molecules.;

Provided herein are methods of drug design comprising using a machine learning model to classify images of tissue samples as being of tissue samples from subject in a first state and tissue samples from subjects in a second state and extracting from the machine learning model groups of biological components comprising at least two biological components whose spatial relationship contributed to the classifying. Methods of drug design, as well as methods of converting a subject from a first state to a second state are also provided.

A fully organic degradable piezoelectric force sensor and a method for preparing the same are disclosed. Amino acid (polypeptide) wafer, preferably isoleucine wafer, under stress-induced alignment, the crystal shows very ordered structure and smooth surface on the mesoscale, which significantly enhances the piezoelectric response. In addition, the force sensor is suitable for long-term detection of physiological movements, including breathing and muscle contraction. More importantly, due to all organic and biological components, the force sensor is biocompatible and completely biodegradable. The compatibility and degradability of the force sensor in the physiological environment make it possible for the development of tissue engineering and implanted biomedical devices.

Measuring device (1c, 1d) for biological components for measuring a component using heat generation of a biological sample (5) that absorbs excitation light (17), wherein the measuring device (1c, 1d) for biological components has the following: an optical medium (10) which has a sample support surface (12) on which the biological sample (5) is arranged, wherein the optical medium (10) is transparent to the excitation light (17) and is made of chalcogenide glass which has a lower thermal conductivity than zinc sulfide, and a refractive index of the optical medium (10) is changed by the heat generation of the biological sample (5) which absorbs the excitation light (17); an excitation light source (16) for emitting the excitation light (17), which moves through the optical medium (10) in the direction of the sample support surface (12); a scanning light source (20) for emitting scanning light (21) which moves through the optical medium (10), a light position detector (25) for detecting the position of the scanning light (21) emerging from the optical medium (10), and a temperature sensor (35) for measuring the temperature of the optical medium (10), wherein the optical medium (10) is also transparent to the scanning light (21), wherein the light position detector (25) detects a first position (22a) of the scanning light (21) exiting the optical medium (10) when the excitation light source (16) does not emit excitation light (17), and a second position (22b) of the scanning light (21) exiting the optical medium (10) in which a refractive index gradient region (18) is generated by the heat generation caused by the excitation light (17) when the excitation light source (16) emits the excitation light (17), where the component is measured based on the first position (22a) and the second position (22b), and wherein the temperature sensor (35) is attached to an area of ​​the sample support surface (12), wherein the area is away from the biological sample (5), the excitation light (17) and the scanning light (21).

Systems for analyzing biological components are provided. The systems may include a fluidic device and an energy source in communication with the fluidic device. The energy source may supply energy to the fluidic device to form a polymer matrix on or adjacent to a biological component within the fluidic device. Methods of using the systems to analyze biological components are also provided.

The invention provides a microbial soil conditioner for in-situ rejuvenation of border trees. The soil conditioner comprises a chemical loosening conditioner (composed of modified sodium carboxymethyl cellulose and citric acid-malic acid composite organic acid), a biological stimulant (composed of bacillus subtilis exopolysaccharide and a seaweed extract) and a physical loosening auxiliary agent (composed of expanded perlite and crushed garden waste). Functional strains (bacillus subtilis and bacillus mucilaginosus) and a protective agent (food-grade sucrose fatty acid ester). According to the invention, a triple synergistic system of chemical loosening-physical supporting, biological stimulation-microbial colonization and nutrient activation-stress tolerance adaptation is constructed, the chemical conditioner rapidly disperses clay particles, the physical auxiliary agent constructs a stable pore skeleton, the biological components promote aggregate formation and microbial colonization, the soil porosity can be increased from less than 15% to 20% or more within 7 days, and the soil quality is improved. The conductivity is reduced to 1.8 mS / cm or below within 30 days, and the pH is adjusted to 6.5-7.5.

The present application relates to a kind of harmless physical method and reagent for treating corn borer.The reagent includes the following mass percentage components: colloid 0.2%-0.6%, diatomite 1%-2%, Bacillus thuringiensis 0.2%-0.3%, Beauveria bassiana 0.1%-0.15%, azadirachtin 0.03%-0.1%, and the balance is water.The present application uses the viscous colloid formed by colloid to effectively occupy corn bell mouth and stick to the corn borer that crawls out to feed, achieving physical control;At the same time, Bacillus thuringiensis and Beauveria bassiana biological components are used to infect and kill the corn borer, azadirachtin plays a role in repelling and growth inhibition, and diatomite can physically pierce the insect skin, enhancing the control effect, and through the synergistic effect of multiple components, biological control is achieved.The present application creatively uses harmless physical method combined with biological components to control corn borer, not only avoiding pesticide residues, but also being more environmentally friendly and safe, and synergistically enhancing the control effect, reducing the worm boring rate.

The present invention pertains to a method of preparing a frozen biological sample, comprising the steps of fixing the biological sample with a non-crosslinking fixative solution, incubating the fixed biological sample in an aqueous solution comprising a cryoprotectant, and freezing the cryoprotected biological sample. The method advantageously allows to preserve both, morphology of the sample as well as biological components such as nucleic acids and proteins, in high quality for subsequent analysis. The method is robust, simple and neither requires laborious steps associated with paraffin-embedding nor immediate freezing of the sample. Also provided are advantageous uses and kits.

System for analyzing biological components in a biological sample, the system comprising a fluid device, the system being configured to perform a procedure comprising: (a) incorporating the fluid device into an apparatus, wherein: the fluid device comprises a microfluidic device or a nanofluidic device, the microfluidic device or the nanofluidic device comprises a chamber, a port and a channel, the chamber, the port and the channel are interconnected and in fluid communication, the channel has a cross-sectional dimension of about 0.1 micrometers (µm) to about 500 µm, and the fluid device comprises the biological sample, the biological sample comprises a plurality of cells, the apparatus includes a temperature controller, and the temperature controller is in thermal communication with the fluid device;(b) Modulating the temperature of the fluid device using the temperature controller; (c) Passing the biological sample through the channel, the device applying overpressure, underpressure, or a combination thereof to the biological sample during flow; (d) Forming a plurality of compartments, each of the at least 10⁵ cells subdividing the plurality of cells, each compartment of the plurality of compartments collectively enclosing a capture element from a plurality of capture elements and a cell of the at least 10⁵ cells, the capture element comprising single-stranded DNA and comprising a unique molecular identifier, a barcode, and a sequencing primer; (e) Lysing at least a portion of the at least 10⁵ cells subdivided in (d), thereby releasing mRNA molecules from at least that portion of the at least 10⁵ cells subdivided in (d);and (f) capturing at least a subset of the mRNA molecules using at least a subset of the plurality of capture elements, thereby obtaining captured mRNA molecules, wherein the capture comprises the attachment of poly(A) sequences of the mRNA molecules or the subset of the mRNA molecules to poly(T) sequences of the plurality of capture elements or the subset of the plurality of capture elements.

The excitation light source (1) emits excitation light that travels through the optical medium (3) toward a sample (5) placed on the sample placement surface. The probe light source (2) emits probe light that travels through the optical medium (3). The light position detector (4) detects the position of the emitted probe light emitted from the optical medium (3). The calculator (11) calculates the amount or concentration of a biological component in the biological material based on the position of the emitted probe light detected by the light position detector (4) when the sample (5) is a reference material that absorbs the excitation light and does not have a specific absorption peak within the excitation wavelength of the excitation light, and the position of the emitted probe light detected by the light position detector (4) when the sample (5) is a biological material.

To provide a filter which is prevented from being clogged.SOLUTION: The filter 1 for filtering an extraction mixture obtained by adding water to a biological component comprises an inner layer 11, an outer layer 15, and a middle layer 13, separates fine particles and large-diameter particles contained in the extraction mixture, and filters the fine particles for trapping the fine particles.SELECTED DRAWING: Figure 1

The present invention relates to a method, an apparatus, and a computer program for preprocessing input data for growth prediction of children or adolescents. The method for preprocessing biological component measurement data for growth prediction according to an exemplary embodiment of the present invention may comprise the steps of: receiving body data of a subject; generating a first variable, on the basis of the body data of the subject; and determining an error in the body data by comparing the first variable with a preset value.

The present invention discloses a photothermal nanomaterial Cu 2‑x The present invention uses a hybrid system Bio-Se to synthesize Se in situ by reducing Na2SeO3 with dissimilatory metal-reducing bacteria. 0 As a semi-artificial photosynthetic system, Cu(II)-EDTA is used as a precursor, and the enzyme catalysis system and semiconductor Se 0 Photocatalysis was carried out by Cu 2‑ x Photocatalytic biosynthesis of Se and its application in photothermal distillation membrane Cu 2‑x Preparation of Se@MR-1@PVDF and desalination of seawater. The method of the present invention removes heavy metal ions Cu(II) and generates high-value products Cu 2‑x Se not only has strong absorption of visible light, but also has a plasma resonance effect (SPR) in the near-infrared range, which makes the distillation membrane have higher photothermal performance; the doped biological components improve the hydrophilicity of the membrane.

The invention discloses a composite nuclear track membrane as well as a preparation method and application thereof. The composite nuclear track membrane comprises a supporting base layer and a two-layer structure membrane formed on the supporting base layer through membrane scraping and finishing, wherein the thickness of the supporting base layer ranges from 50 micrometers to 120 micrometers, the thickness of the two-layer structure membrane ranges from 10 micrometers to 50 micrometers, and the two-layer structure membrane comprises a compact layer and a loose layer; the thickness of the compact layer is 100-200 nm, the aperture of the compact layer is 0-40 nm, the thickness of the loose layer is 10-50 [mu] m, and the aperture of the loose layer is 0.1-10 [mu] m; the composite nuclear track membrane is applied to the biological component separator. The composite nuclear track membrane as well as the preparation method and the application thereof aim at solving the problems of a dialysis membrane used by a biological component separator in the prior art so as to meet the requirement for accurate separation of biological substances in medical and biological experiments, and have important practical significance.

An inoculant composition has a first fungal species or strain and a different second fungal species or strain. At least one of the first fungal species or strain is a saprophytic fungi. Each of the first and second fungal species or strain is present in a relative concentration that within the composition to allow inoculation on one or more polymer materials at an inoculation ratio of no greater than 1:1 fungal biomass to polymer material mass. Additionally, an inoculant can include a first engineered fungal species or strain that recognizes plastic products as a food source and digest recalcitrant long-chain carbons more efficiently than a naturally occurring counterpart of the same species or strain. The first engineered fungal species or strain may be immobilized rendering it dormant from metabolism. A method for transforming long chain carbon materials in plastic waste includes adding an inoculum to a plastic substrate.