The invention relates to an office chair, in particular to an office chair with multiple massage functions. Technically, the invention aims to provide the office chair that has multiple massage functions, can relieve fatigue and promote blood circulation, and is beneficial to health. The office chair with multiple massage functions provided by the invention includes a box body, a seat plate, a back board, wheels, a mounting seat, a motor, a disk, a first connecting rod, a vertical rod, a first guide sleeve, a first guide rod and the like. The top of the box body is connected to the seat plate,the right side of the seat plate is connected to the back board, the plurality of evenly spaced wheels are connected at the bottom of the box bottom, and an opening is disposed at the lower part of the box body right side. Through constant left and right movement of massaging balls, the office chair can achieve massage to the back, and can relieve fatigue and promote blood circulation, and through the piston motion, the office chair can relieve the discomfort caused by long-term sitting, thereby reaching the effects of relieving fatigue, promoting blood circulation and facilitating good health.