The application discloses a dMRI
data reconstruction method, device, medium and program product, relates to the technical field of neural
image computing, and comprises the following steps: acquiring undersampled scanning data, wherein the scanning data comprises a zero
diffusion image, a structural image, and a plurality of first
diffusion weighted images collected under a plurality of different first sampling conditions; performing
signal decomposition on each first
diffusion weighted image through the zero diffusion image to obtain a plurality of diffusion
signal components; determining a condition guided
signal from the plurality of diffusion signal components according to a preset target sampling condition, wherein the condition guided signal is used for guiding a
generative model to generate diffusion characteristics under the target sampling condition; taking the zero diffusion image, the structural image and the condition guided signal as multi-channel input data, inputting the multi-channel input data and the target sampling condition into a pre-trained
generative model, and outputting dMRI data under the target sampling condition. The application realizes high-quality, fast and stable reconstruction of dMRI data.