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86 results about "Optimal alignment" patented technology

An optimal alignment is an alignment giving the highest score, and alignment score is this highest score. the alignment score of X and Y = the score of X and Y under an optimal alignment.

Method for detecting DNA sequence similarity by using one-dimensional cell neural network

The invention discloses a method for detecting DNA sequence similarity by using a one-dimensional cell neural network. The method comprises the steps of: firstly, designing a one-dimensional cell neutral network basic model and then establishing a one-dimensional dual cell neutral network by utilizing the model; then initializing the network by using information of two to-be-detected DNA sequences; recording a cell state and an output in the network at each moment during the network operation process and accordingly forming an optimized output matrix; then traversing elements in the optimized output matrix so as to determine an optimal alignment path; finally, performing blank insertion operation on the two sequences based on the alignment path so as to finish the global alignment of the two sequences conveniently; after the sequences are aligned, calculating the global similarity based on the number of aligned basic groups and the total number of the basic groups. As shown by the test and contrast, the necessary calculation time of the method for detecting the DNA sequence similarity by using the one-dimensional cell neural network is obviously reduced to a great extent than that needed by the existing method for the DNA sequences in relatively long length while the detection precision is guaranteed.
Owner:UNIV OF ELECTRONICS SCI & TECH OF CHINA
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