7 results about "Oxalate crystals" patented technology

The invention provides a preparation method of ferrous oxalate, which comprises the following steps: S1, mixing and grinding fine iron powder and alkali, and roasting the obtained mixed material to obtain a roasted material; s2, mixing the roasted material with water and polyhydric alcohol for water leaching, and taking a solid phase after solid-liquid separation to obtain primary filter residues; and S3, mixing the primary filter residues with an acid solution, carrying out acid leaching, adjusting the pH value, carrying out solid-liquid separation, taking a solid phase to obtain secondary filter residues, mixing the secondary filter residues with oxalic acid and a reducing agent, and carrying out a heating reaction to generate ferrous oxalate crystals. The invention aims to develop an alkali roasting-water leaching-acid leaching and precipitation process, so that silicon, aluminum, boron, calcium and magnesium impurities in the fine iron powder are efficiently and synergistically removed, and ferrous oxalate with high additional value is mainly produced.

This application provides a method for deep removal of calcium impurities from scandium oxide, belonging to the field of rare earth metal oxide purification. The method includes: dissolving scandium oxide raw material containing calcium impurities to obtain a calcium-containing scandium solution; adding a pH adjuster to the calcium-containing scandium solution to obtain a first scandium solution; reacting the first scandium solution with phosphoric acid and / or phosphate to obtain a second scandium solution and solid calcium phosphate; reacting the second scandium solution with a complexing agent to obtain a third scandium solution; reacting the third scandium solution with oxalic acid and / or sodium oxalate to obtain scandium oxalate crystals and a calcium complex solution; adding a strong acid solution to the calcium complex solution; and calcining the scandium oxalate crystals to obtain scandium oxide. Through calcium phosphate precipitation-complexation-crystallization, not only can calcium impurities be deeply removed from scandium oxide products, but impurities such as iron, titanium, and zirconium can also be removed, resulting in scandium oxide products with a purity of over 99.99%.

The invention discloses a liposome preparation prepared from a benzoyl guanidine derivative LY104 crystal form as well as a preparation method and application of the liposome preparation, and belongs to the technical field of medicines. The invention provides a liposome for inflammatory lung diseases, which takes LY104 and a novel crystal form thereof as active ingredients. The liposome prepared by the invention is good in stability, stable in membrane drug loading, and suitable for atomization drug delivery, and the particle size can be controlled to be 50-200nm. Meanwhile, the liposome preparation provided by the invention can delay drug release, prolong the onset time, improve the tolerated dose of single administration, reduce drug irritation, and can be used for treating inflammatory lung diseases, after being freeze-dried, the liposome preparation provided by the invention is dispersed in saline water to be atomized and inhaled, so that the bitter taste of the drug can be greatly covered, and the bioavailability of the drug is improved. The lipidosome preparation has the advantages that drug irritation is reduced, drug bioavailability is improved, patient compliance is improved, the lipidosome preparation can optimize the in-vivo metabolic process of the benzoyl guanidine derivative, the curative effect of the benzoyl guanidine derivative on treating inflammatory lung diseases is enhanced, and the application prospect is wide. The liposome preparation provided by the invention can be used for treating inflammatory lung diseases such as asthma, chronic obstructive pulmonary disease and the like in a more targeted manner, and has a wide market application prospect.

The invention provides a preparation method of an aluminum-containing oxalate piezo-electric crystal. The chemical formula of the aluminum-containing oxalate piezo-electric crystal is NaBaAl (CO). 5HO, the molecular weight is 541.45, the aluminum-containing oxalate piezo-electric crystal is crystallized in an orthorhombic system polar space group Pca2 (No.29), and the cell parameters are as follows: a = 19.0829 (4), b = 10.8321 (3), c = 16.4577 (4), alpha = beta = gamma = 90 degrees, V = 3401.94 (14) 3 and Z = 8. The aluminum-containing oxalate crystal realizes a non-centrosymmetric structure so as to have piezoelectric response, d33 of the aluminum-containing oxalate crystal is obviously higher than that of quartz, meanwhile, the problem of environmental pollution of a Pb-based material is avoided, and a feasible solution is provided for developing a novel green and high-performance piezoelectric material.

The utility model relates to a rare earth recovery device, belongs to the technical field of rare earth recovery, and particularly relates to a rare earth recovery device for rare earth wastewater solution, which comprises a cooling box, a top cover is fixedly connected onto the cooling box, a precipitation cylinder is fixedly connected onto the top cover, and a feeding pipe is fixedly connected onto the top cover; according to the praseodymium neodymium oxalate crystal discharging device, the sliding groove, the sliding block, the filter screen, the rotating shaft and the hydraulic rod are matched, the hydraulic rod is used for driving the filter screen to move upwards, praseodymium neodymium oxalate crystals move upwards along with the filter screen, the praseodymium neodymium oxalate crystals are separated from rare earth waste water through the filter screen, and the situation that waste water rare earth is discharged when the praseodymium neodymium oxalate crystals are discharged is effectively avoided; through cooperation of the protective shell, the motor, the rotating shaft, the scraping strip and the scraping plate, the motor is used for driving the scraping strip to rotate to prevent praseodymium neodymium oxalate crystals from blocking the filter screen, the scraping strip is used for driving the scraping plate to rotate to clean the inner wall of the precipitation barrel, and the praseodymium neodymium oxalate crystals are prevented from adhering to the inner wall of the precipitation barrel to cause waste.

The application belongs to the technical field of crystal form drug molecules, and particularly relates to an axitinib oxalate crystal form and a preparation method and application thereof. The axitinib oxalate crystal form provided by the application is composed of one molecule of axitinib, one molecule of oxalic acid and two molecules of water as a basic unit of the crystal form, has high solubility, good stability, a simple preparation method, good reproducibility and is suitable for industrialized production.

A method for preparing ferrous oxalate includes: dissolving an iron source and performing a reduction operation to obtain a first solution; adding a first liquid oxalic acid to the first solution and mixing and reacting to obtain a second solution; adding solid oxalic acid to the second solution and mixing and reacting to obtain a third solution containing a first reaction product; and removing impurities from the first reaction product to obtain ferrous oxalate. The ferrous oxalate has particle sizes including D10, D50, and D90, and its uniformity coefficient is (D90-D10) / D50, satisfying: 20μm≤D50≤60μm, 1.8≤(D90-D10) / D50≤8. This method can prepare both small- and large-particle-size ferrous oxalate, thus broadening the particle size range of ferrous oxalate crystals.