A multi-scale biomimetic artificial bone scaffold additive manufacturing method, mixing biopolymer materials and bioceramic materials with deionized water or organic solvents to form a uniform slurry, then freeze-drying to obtain a homogeneous powder, and then Mix and stir with deionized water or organic solvent, after vacuum exhaust, quantitatively extrude through screw pump, use XYZ movement device, according to the three-dimensional geometric model of bone defect obtained from CT scan, design the shape of the pores inside the geometric model through computer program , size and porosity, the movement trajectory of the extruded material, to complete the additive manufacturing. Using biodegradable biocomposite materials, the bone defect will eventually be replaced by the human body's own tissue to meet the lifelong growth requirements of the human body. Directly use the screw pump to quantitatively extrude the required biomaterials, the dosage is precise and controllable, and the clinical application cost of artificial bone is significantly reduced. This method has the advantages of accurate printing material dosage, wide application range of materials, precise and adjustable pore structure, and free shaping of macroscopic geometric shape.