33 results about "Transurethral route" patented technology

The invention relates to a balloon catheter for transurethral use, having a proximal region (2) comprising an at least single-lumen catheter shaft (4) with an inflation lumen and an inflatable balloon (5) connected to the distal end of the inflation lumen in a fluid-permeable manner, and a distal region (3) comprising a distal shaft (7) and a distal tip (9). The balloon (5) is coated with a medication and a placement aid (10) is provided at least in the proximal region (2). The placement aid (10) is tubular at least in the region of the balloon (5), and the tubular section has a length at least equal to the length of the balloon (5). The balloon catheter according to the invention allows the conservative treatment of benign prostatic hyperplasia without the use of additional imaging techniques.

The present invention relates to a small-caliber bipolar plasma resectoscope, comprising an outer sheath, an inner sheath, and an electrode loop assembly. The electrode loop assembly is installed in the inner sheath and can move along the extension direction of the inner sheath. The electrode loop assembly comprises a linearly distributed positive electrode, an insulator, and a negative electrode, which are fixedly connected in sequence. The positive electrode comprises an extension section, a first bending section, and a second bending section. The extension direction of the first bending section forms a first angle with the horizontal plane. The extension direction of the second bending section forms a second angle with the horizontal plane. When energized, the positive electrode and the negative electrode form an electrical circuit with the physiological saline perfused in the electrode loop. While meeting normal electroresection conditions, the resectoscope increases the cutting and hemostasis efficiency of a simple linear electrode loop, achieves the goal of reducing the circumference of the resectoscope outer sheath to a minimum of Fr16, meets the needs of transurethral / cervical surgery for patients with a small urethral circumference or urethral / cervical stenosis, and reduces the problems of urethral / cervical injury and postoperative urethral / cervical stenosis caused by the excessive circumference of a conventional Fr26 resectoscope.

The utility model relates to a kind of self-urination metal catheter, it includes the catheter body woven by metal wire, the distal end of catheter body is provided with bending anti-off structure to prevent the distal end of catheter body from being outwardly off from bladder in indwelling state, the proximal end of catheter body is close to external sphincter after passing through prostate area, the proximal end of catheter body is connected with fixed anchor placed in urethra by connecting line, fixed anchor is located at the outside of external sphincter and cannot slide to prostate area inwardly by the block of external sphincter, one end of fixed anchor is connected with traction rope, the other end of traction rope is stretched to patient's outside through urethra.The advantages are that new structure and material are used, infection risk can be effectively reduced, catheter indwelling time is prolonged, and stimulation to urethra or other urinary tissues is reduced;Catheter indwelling period does not need to use urine bag, and patient can self-control urination, improve life quality;Catheter body woven by metal wire is moderately soft and hard, and has good self-adaptability.

The present application relates to a sampling specimen bag for transurethral bladder surgery, and relates to the technical field of medical devices. The sampling specimen bag for transurethral bladder surgery comprises an outer tube, an inner tube, a movable rod, an elastic member, a specimen bag body, a locking mechanism, and a driving mechanism. The inner tube is rotatably connected to the outer tube via the driving mechanism. The movable rod is coaxially arranged in the inner tube, wherein a portion of the movable rod is located in the inner tube and the other portion of the movable rod is located in the outer tube. The locking mechanism is arranged in the inner tube for fixing the inner tube and the movable rod. The elastic member is arranged at the end of the movable rod. The specimen bag body is arranged on the elastic member. The elastic member has an expanded state and a contracted state. When the elastic member is in the expanded state, the end of the movable rod with the elastic member extends out of the outer tube, and the specimen bag body opens. When the elastic member is in the contracted state, the end of the movable rod with the elastic member is located in the outer tube, and the specimen bag body closes. The present application has the effect of facilitating the insertion of specimens.

The invention provides a sorbitol and mannitol flushing fluid for urinary surgery. The invention relates to a freeze-dried powder injection, which comprises 20 to 50 grams of sorbitol, 10 to 30 grams of mannitol, 5 to 10 grams of sodium bicarbonate and 0.5 to 2 grams of sodium citrate in every 1000 milliliters of the freeze-dried powder injection, and the pH value of the freeze-dried powder injection is adjusted to 7.2 to 7.4. The preparation method comprises the following steps: heating distilled water to 80 DEG C, sequentially adding the components, continuously stirring until the components are completely dissolved, cooling to room temperature, fixing the volume to 1000ml, adjusting the pH value by using a 5mol / L sodium hydroxide solution, finally sterilizing by using a 0.22-micron microporous filter membrane, and packaging in a sterilized glass bottle. The flushing fluid can effectively dissolve blood clots, stones and necrotic tissues in an operation field by utilizing the high osmotic pressure characteristics of the sorbitol and the mannitol, so that the operation field is kept clear. The flushing fluid disclosed by the invention shows an excellent flushing effect and good safety in urinary surgery operations such as transurethral bladder tumor electrocision, flexible ureteroscope calculus removal and the like.

A transurethral system for delivering and depositing fiducial markers usable to delineate the prostate during radiation therapy includes at least one implant or anchor assembly featuring a first anchoring component, a second anchoring component, and a connector. A delivery device featuring a handle assembly, an actuator, and an elongate member delivers the implant or anchor assembly to an interventional site.

The invention discloses a construction method, system, equipment, product and medium for an ablation protection area, and the method comprises the steps: obtaining a cross-sectional image set of a prostate target area, the cross-sectional image set comprising a first cross-sectional image comprising a bladder neck and at least one second cross-sectional image comprising verumontanum; according to the first cross section image, a first boundary contour corresponding to the bladder neck is determined, and the first boundary contour covers the sphincter in the urethra; according to the second cross section image, a second boundary contour corresponding to the verumontana is determined, and the second boundary contour covers the verumontana; according to the first boundary contour and the at least one second boundary contour, the ablation protection area in the prostate target area is determined, the problem that definition of a functional structure depends on subjective judgment of clinical experience is solved, the quantitative protection standard of the functional anatomical axis from the bladder neck to the prostatic urethra to the verumontana is achieved, and the protection effect is improved. The risk of urination function impairment and sexual function impairment induced by transurethral ablation operation is effectively controlled.

The present invention relates to a method for providing information for predicting the likelihood of bladder cancer recurrence, which provides information that patients who have undergone transurethral resection of a bladder tumor and test positive for suspicious high-grade urothelial carcinoma (SHGUC) or high-grade urothelial carcinoma (HGUC) in a urine cytology test have a higher likelihood of bladder cancer recurrence compared with patients who do not test positive.

To create an implant that allows for easy and reliable treatment of the bladder neck. [Solution] This is achieved by an implant having a pressurizing means structure for expanding the bladder neck of a person, particularly a removable implant. This pressurizing means structure applies local pressure to the tissue of the bladder neck. The pressurizing means structure may be connected to a retaining means for operation. This retaining means may be a wire, thread, or rod, and the retaining means is used to insert the implant or pressurizing means structure into the bladder neck via the urethra, and, if necessary, to retrieve the pressurizing means structure from the patient's body after the treatment is completed.

The invention discloses a minimally invasive surgery treatment system for benign prostatic hyperplasia and a use method of the minimally invasive surgery treatment system. The system comprises an outer cannula used for entering the body of a patient through the urethra, a handle connected to the outer cannula, a cannula installed in the outer cannula, a stretching tube installed in the cannula, a guide wire installed in the stretching tube, a puncture needle head installed at the free end of the guide wire, a rotation driving mechanism used for driving the guide wire to rotate and a telescopic driving mechanism used for driving the cannula to move. A plurality of cutting knives which are uniformly arranged around the stretching tube are arranged between the free end of the stretching tube and the puncture needle head; a magnetic ring which is magnetically attracted with the puncture needle head is arranged at the free end of the sleeve; a guide wire locking mechanism used for locking the guide wire and a stretching pipe adjusting and locking mechanism used for adjusting the position of the stretching pipe and locking the stretching pipe are further arranged in the handle. The system is reasonable in structural design, the telescopic cutting knife is integrated into the puncture assembly, when the system is used for operation, trauma is small, recovery is fast, only local anesthesia is needed, the effect is fast, and the operation effect is good.

A delivery device for image-assisted delivery of an implantable expander in a urethra. An implantable biocompatible expander suitable for implantation into a urinary duct is resiliently deformable from a relaxed radially expanded orientation to a radially contracted orientation suitable for transluminal delivery through the urinary duct. The expander may be configured to exert an outward radial force against a wall of the urinary duct when in-situ within the urinary duct. In particular, the expander is suitable for treatment of benign prostatic hyperplasia and configured for implantation into the prostatic urethra between, and substantially spanning the prostatic urethra between, the bladder neck and external sphincter.

Provided herein are methods and systems for cancer detection and monitoring. The methods may include minimal residual disease analysis. The methods may include using nucleic acids from a urine sample or a urine cell pellet sample. The methods may include assaying nucleic acids in urine to detect a set of biomarkers from the sample. The methods may include monitoring a subject after transurethral bladder tumor resection.

The invention discloses a seminal vesicle endoscope identification and positioning system based on a visual enhancement technology, and relates to the technical field of visual detection. A seminal vesicle endoscope is placed into a prostate small vesicle cavity through the urethra, and white light, fluorescent light and near-infrared images are synchronously collected through a three-channel CMOS sensor; extracting a fluorescence characteristic pattern, a scattering gradient characteristic pattern and a white light edge characteristic pattern, and fusing through an RGB thermodynamic diagram synthesis function; optimizing the learning rate of the convolutional neural network by using a genetic algorithm, training a weak region separation model to output a real-time weak region mask, screening a target spot in combination with a centroid, and marking the target spot; in the puncture stage, a tactile feedback needling instrument is integrated, resistance is monitored in real time, threshold response is set, drainage is verified through flushing, and the operation effect is confirmed through a double-black-hole wall breaking channel under a white light microscope; the multi-mode imaging fusion bottleneck is broken through, the weak area in the operation is accurately positioned, the puncture complication risk is reduced, the success rate of a single operation is improved, and a full-chain intelligent positioning navigation scheme is provided for minimally invasive treatment of seminal vesicle diseases.

A delivery tube for image-assisted positioning an implantable expander in a prostatic urethra. An implantable biocompatible expander suitable for implantation into a urinary duct is resiliently deformable from a relaxed radially expanded orientation to a radially contracted orientation suitable for transluminal delivery through the urinary duct. The expander may be configured to exert an outward radial force against a wall of the urinary duct when in-situ within the urinary duct. In particular, the expander is suitable for treatment of benign prostatic hyperplasia and configured for implantation into the prostatic urethra between, and substantially spanning the prostatic urethra between, the bladder neck and external sphincter.

The utility model relates to a specimen collecting device for transurethral electric resection, belongs to the technical field of medical instruments, and solves the technical problem that the existing specimen collecting device is easy to mix surgical specimens at different parts. The device comprises a waste liquid collecting container, a loader, a specimen collector and a sealing cover, wherein the loader is rotationally arranged in the waste liquid collecting container; a plurality of specimen collectors are arranged, and the plurality of specimen collectors are circumferentially arranged on the loader; the sealing cover is buckled at the opening of the waste liquid collecting container and is connected with the resectoscope sheath; and by rotating the loader, different specimen collectors can be switched to perform targeted collection on specimens at different parts. According to the utility model, different specimen collectors are switched by rotating the loader, so that specimens at different parts can be independently collected without replacing a new specimen collection device during multi-point focus tissue excision, and the confusion of surgical specimens at different parts is avoided.

The utility model discloses a medical filterable small pathological tissue specimen bag, including specimen bag body and the top sealing press -fitting strip of setting in the inside of specimen bag body top end opening, the bottom sealing press -fitting strip of specimen bag body bottom end opening inside is provided with, the top sealing press -fitting strip and bottom sealing press -fitting strip and specimen bag body inner wall between close adhesion, and top sealing press -fitting strip and bottom sealing press -fitting strip and specimen bag body junction still adopt the encryption processing of sealing glue, the inside of specimen bag body is provided with filter screen, the filter screen is plastic dense mesh, the medical filterable small pathological tissue specimen bag of this new type is applicable to the collection pathological specimen when transurethral resection of prostate plasma cutting, laser enucleation, cystectomy, reduces the tissue collection time, reduces the pathological tissue loss risk, improves pathological tissue quality, increases the operation efficiency, solves the problem of time -consuming and labor -intensive when specimen collection, smaller tissue loss.

A transvaginal stimulation device incorporates various securing mechanisms configured to maintain secure engagement between the treatment portion of a transvaginal stimulation device and target tissue to increase the efficacy of therapeutic stimulation treatment. The device includes a concave portion configured with a stimulation array of electrodes, and the securing mechanism maximizes engagement between the stimulation array and the tissue to be treated. The device includes a flexible mechanism that increases the ability of the device to conform to the vaginal canal to maximize electrode contact. The securing mechanisms may be manually controlled or automatically controlled using predictive models trained using patient data. The predictive models may include machine learning models trained to dynamically modify device position and / or therapy in response to receipt of real-time information.

The invention discloses a multifunctional radiofrequency ablation catheter for non-invasive treatment of prostatic hyperplasia through urethra and a synergistic device. The multifunctional radiofrequency ablation catheter and the synergistic device integrate the five functions of radiofrequency ablation, circulating cooling, catheterization flushing, balloon fixing and temperature sensing. The radiofrequency ablation system is composed of a radiofrequency generator, a circular-tube-shaped radiofrequency ablation electrode and a dispersion electrode. The cooling system is composed of a double-channel cooling circulation pipeline, an embedded temperature sensor, a peristaltic pump and a cold constant-temperature water tank. The urethral catheterization system comprises a drainage tube cavity, a flushing tube cavity, a balloon tube cavity and a front-end expandable balloon. The in-vitro control system is composed of an integrated multi-parameter monitoring module, a control panel and a data record. Based on the unique cognition that the radio frequency ablation metal electrode does not produce heat, precise ablation and catheterization flushing of hyperplastic prostate tissue are synchronously achieved through urethral intervention. The non-invasive radio frequency energy control and cooling technology can effectively protect the urethral mucosa, and has the advantages of efficient treatment, safe operation and rapid recovery.

Provided herein are methods and systems for detecting and monitoring cancer. The methods may include minimal residual disease analysis. The method may include using nucleic acids from a urine sample or a urine cell precipitate sample. The method may include determining nucleic acids in urine to detect a panel of biomarkers from a sample. The method may include monitoring the subject after transurethral bladder tumor resection.

A transvaginal stimulation device incorporates various securing mechanisms configured to maintain secure engagement between the treatment portion of a transvaginal stimulation device and target tissue to increase the efficacy of therapeutic stimulation treatment. The device includes a concave portion configured with a stimulation array of electrodes, and the securing mechanism maximizes engagement between the stimulation array and the tissue to be treated. The device includes a flexible mechanism that increases the ability of the device to conform to the vaginal canal to maximize electrode contact. The securing mechanisms may be manually controlled or automatically controlled using predictive models trained using patient data. The predictive models may include machine learning models trained to dynamically modify device position and / or therapy in response to receipt of real-time information.

Provided are stable, concentrated, and palatable solutions suitable for sublingual and / or transurethral administration containing tadalafil, with or without other active ingredients to address comorbidities, in a liquid vehicle or solvent selected from propylene carbonate, 2-pyrrolidone, dimethyl isosorbide, dimethyl acetamide, n-methyl-2-pyrrolidone, ethanol, water, oleic acid, and isopropyl myristate. The solutions have low irritancy for sublingual tissues and a-are compatible with commercial atomizers. The invention is further directed to methods of treating male erectile dysfunction and / or comorbidities by administering an effective amount of the pharmaceutical formulations comprising tadalafil, with or without other active ingredients, to a patient in need of such treatments.

The invention discloses a targeted drug delivery biological hybrid micro-robot as well as a preparation method and application thereof. The micro-robot takes sperms as an active propulsion unit, and is constructed by combining PDA-DOX-FA nanoparticles through a coupling strategy; stable coupling of sperms and nanoparticles is realized through electrostatic adsorption, a biotin-streptavidin system or covalent binding. The micro-robot can enter the bladder through urethra perfusion, arrives at a tumor area depending on the autonomous propelling speed of sperms, realizes stable retention through folic acid targeted recognition and adhesion of neutrophil extracellular trapping nets (NETs), and realizes controllable release of adriamycin and deep penetration of tumors through a photothermal effect triggered by 808 nm near-infrared light. The problems of short retention, non-uniform distribution, insufficient permeation and the like of traditional bladder cancer perfusion treatment medicines are solved, the treatment efficiency and safety are remarkably improved, and the method is suitable for local precise treatment of bladder cancer.

1. Name of the design product: Suspension patch (butterfly shape). 2. Use of the design product: Medical device for in-vivo implantation, surgical supplies for transurethral mid-urethral tension-free suspension surgery for female stress urinary incontinence. 3. Design key points of the design product: Lies in the shape. 4. Picture or photograph that best shows the design key points: Front view. 5. Other circumstances that need to be explained: Other explanation: The suspension patch of this application is a solid structure.

The invention provides an implant for the simple and reliable treatment of a bladder neck. This is achieved by a removable implant in which a pressure-mediating structure is used to dilate the bladder neck. This structure exerts local pressure on the bladder neck tissue. The pressure-mediating structure can be connected to a retention element for handling. This retention element, which can be a wire, thread, or rod, serves to insert the implant or pressure-mediating structure through the urethra into the bladder neck and, if necessary, to remove the structure from the patient's body after the treatment is completed.

The invention relates to the technical field of medical instruments for urinary surgery, in particular to a transurethral bladder sheath. The transurethral bladder sheath is composed of a transurethral bladder sheath body, a bladder sheath outer pipe body, a movable bladder sheath inner core head, a bladder sheath inner pipeline, a movable bladder sheath inner core rod, a bladder sheath pipe check ring, a negative pressure suction water outlet pipeline and a movable transurethral bladder sheath rear cover. The bladder sheath is characterized in that a hollow negative pressure suction water outlet pipeline with an included angle of 60 degrees is arranged between the lower portion of the left front portion of the bladder sheath tube check ring and the horizontal transurethral bladder sheath body, and the negative pressure suction water outlet pipeline is communicated with the bladder sheath inner pipeline. Due to the adoption of the negative pressure suction water outlet pipeline, the transurethral bladder sheath can realize sustainable perfusion, negative pressure suction and waste liquid discharge and complete self-control perfusion during an operation, ensures safe internal pressure of a bladder cavity, keeps a clear view in the whole process of the operation, improves the lithotripsy efficiency, effectively simplifies the operation, relieves the operation fatigue, improves the efficiency and shortens the operation time; and the operation of a patient is safer.

The invention relates to the technical field of catheter suites, and discloses a multifunctional catheter suite and a using method thereof. The filling unit comprises an air bag and a water injection pipe which are arranged on the catheter, and the air bag is of a conical structure. Basically, all transurethral prostatic hyperplasia operation modes need to retain catheterization, the catheter air bag is pulled to the bladder neck opening, the conical air bag can press the bladder neck opening in a wedging mode after being expanded, the catheter is pulled and fixed in combination with the fixing unit, prostatic wound bleeding is effectively blocked, and bladder blood clot filling is prevented. And aiming at difficult urethral catheterization and urethral stricture possibly occurring in a prostate operation, the guide wire dilation strip and the catheter with the front end opened can successfully complete difficult urethral catheterization and safe urethral dilation. The expansion strip adopts a bionic morphological design that the first expansion section is arc-shaped and the second expansion section is bent, and is combined with a diameter gradual change structure from thin to thick, so that progressive physical expansion is realized.

A delivery tube for image-assisted positioning an implantable expander in a prostatic urethra. An implantable biocompatible expander suitable for implantation into a urinary duct is resiliently deformable from a relaxed radially expanded orientation to a radially contracted orientation suitable for transluminal delivery through the urinary duct. The expander may be configured to exert an outward radial force against a wall of the urinary duct when in-situ within the urinary duct. In particular, the expander is suitable for treatment of benign prostatic hyperplasia and configured for implantation into the prostatic urethra between, and substantially spanning the prostatic urethra between, the bladder neck and external sphincter.

This invention discloses a transurethral prostate surgery robot system and its collaborative control method. The system includes an actuator carriage, a controller carriage, and an RCM positioning unit. The actuator carriage includes a surgical robotic arm, an ultrasonic robotic arm, a transrectal ultrasound probe, a binocular video recognition system, and a display. The RCM positioning unit, in conjunction with the binocular video recognition system, uses optical markers to determine the RCM1 point at the surgical entry point. The physiological opening corresponding to the insertion end of the transrectal ultrasound probe is determined by the control system as the RCM2 point. The control system establishes a screw coordinate system based on the RCM1 and RCM2 points, performs RCM-constrained kinematics solutions, and achieves collaborative control of the two robotic arms. This system can integrate and display endoscopic views and ultrasound-guided images, and combines force feedback and virtual fences to improve operational accuracy and safety. It is suitable for minimally invasive surgeries such as transurethral resection of the prostate (TURP) and laser enucleation.

The invention discloses a real-time identification method for a focus boundary of a transurethral prostate resection operation, and the method employs an artificial intelligence image recognition technology, achieves the dynamic monitoring and precise calibration of a prostate surgical boundary through the real-time collection and analysis of endoscopic image data in an operation process, and achieves the real-time recognition of the focus boundary of the transurethral prostate resection operation. In the transurethral prostate resection operation process, focus classification and positioning are achieved in real time, so that the problem of wrong cutting or missed diagnosis caused by view limitation or inadequate experience of doctors is effectively solved, and the urology surgeons are guided to conduct more efficient and more accurate operation.