16 results about "Transurethral route" patented technology

The utility model relates to a kind of self-urination metal catheter, it includes the catheter body woven by metal wire, the distal end of catheter body is provided with bending anti-off structure to prevent the distal end of catheter body from being outwardly off from bladder in indwelling state, the proximal end of catheter body is close to external sphincter after passing through prostate area, the proximal end of catheter body is connected with fixed anchor placed in urethra by connecting line, fixed anchor is located at the outside of external sphincter and cannot slide to prostate area inwardly by the block of external sphincter, one end of fixed anchor is connected with traction rope, the other end of traction rope is stretched to patient's outside through urethra.The advantages are that new structure and material are used, infection risk can be effectively reduced, catheter indwelling time is prolonged, and stimulation to urethra or other urinary tissues is reduced;Catheter indwelling period does not need to use urine bag, and patient can self-control urination, improve life quality;Catheter body woven by metal wire is moderately soft and hard, and has good self-adaptability.

The invention provides a sorbitol and mannitol flushing fluid for urinary surgery. The invention relates to a freeze-dried powder injection, which comprises 20 to 50 grams of sorbitol, 10 to 30 grams of mannitol, 5 to 10 grams of sodium bicarbonate and 0.5 to 2 grams of sodium citrate in every 1000 milliliters of the freeze-dried powder injection, and the pH value of the freeze-dried powder injection is adjusted to 7.2 to 7.4. The preparation method comprises the following steps: heating distilled water to 80 DEG C, sequentially adding the components, continuously stirring until the components are completely dissolved, cooling to room temperature, fixing the volume to 1000ml, adjusting the pH value by using a 5mol / L sodium hydroxide solution, finally sterilizing by using a 0.22-micron microporous filter membrane, and packaging in a sterilized glass bottle. The flushing fluid can effectively dissolve blood clots, stones and necrotic tissues in an operation field by utilizing the high osmotic pressure characteristics of the sorbitol and the mannitol, so that the operation field is kept clear. The flushing fluid disclosed by the invention shows an excellent flushing effect and good safety in urinary surgery operations such as transurethral bladder tumor electrocision, flexible ureteroscope calculus removal and the like.

The invention discloses a construction method, system, equipment, product and medium for an ablation protection area, and the method comprises the steps: obtaining a cross-sectional image set of a prostate target area, the cross-sectional image set comprising a first cross-sectional image comprising a bladder neck and at least one second cross-sectional image comprising verumontanum; according to the first cross section image, a first boundary contour corresponding to the bladder neck is determined, and the first boundary contour covers the sphincter in the urethra; according to the second cross section image, a second boundary contour corresponding to the verumontana is determined, and the second boundary contour covers the verumontana; according to the first boundary contour and the at least one second boundary contour, the ablation protection area in the prostate target area is determined, the problem that definition of a functional structure depends on subjective judgment of clinical experience is solved, the quantitative protection standard of the functional anatomical axis from the bladder neck to the prostatic urethra to the verumontana is achieved, and the protection effect is improved. The risk of urination function impairment and sexual function impairment induced by transurethral ablation operation is effectively controlled.

The present invention relates to a method for providing information for predicting the likelihood of bladder cancer recurrence, which provides information that patients who have undergone transurethral resection of a bladder tumor and test positive for suspicious high-grade urothelial carcinoma (SHGUC) or high-grade urothelial carcinoma (HGUC) in a urine cytology test have a higher likelihood of bladder cancer recurrence compared with patients who do not test positive.

To create an implant that allows for easy and reliable treatment of the bladder neck. [Solution] This is achieved by an implant having a pressurizing means structure for expanding the bladder neck of a person, particularly a removable implant. This pressurizing means structure applies local pressure to the tissue of the bladder neck. The pressurizing means structure may be connected to a retaining means for operation. This retaining means may be a wire, thread, or rod, and the retaining means is used to insert the implant or pressurizing means structure into the bladder neck via the urethra, and, if necessary, to retrieve the pressurizing means structure from the patient's body after the treatment is completed.

A delivery device for image-assisted delivery of an implantable expander in a urethra. An implantable biocompatible expander suitable for implantation into a urinary duct is resiliently deformable from a relaxed radially expanded orientation to a radially contracted orientation suitable for transluminal delivery through the urinary duct. The expander may be configured to exert an outward radial force against a wall of the urinary duct when in-situ within the urinary duct. In particular, the expander is suitable for treatment of benign prostatic hyperplasia and configured for implantation into the prostatic urethra between, and substantially spanning the prostatic urethra between, the bladder neck and external sphincter.

Provided herein are methods and systems for cancer detection and monitoring. The methods may include minimal residual disease analysis. The methods may include using nucleic acids from a urine sample or a urine cell pellet sample. The methods may include assaying nucleic acids in urine to detect a set of biomarkers from the sample. The methods may include monitoring a subject after transurethral bladder tumor resection.

A delivery tube for image-assisted positioning an implantable expander in a prostatic urethra. An implantable biocompatible expander suitable for implantation into a urinary duct is resiliently deformable from a relaxed radially expanded orientation to a radially contracted orientation suitable for transluminal delivery through the urinary duct. The expander may be configured to exert an outward radial force against a wall of the urinary duct when in-situ within the urinary duct. In particular, the expander is suitable for treatment of benign prostatic hyperplasia and configured for implantation into the prostatic urethra between, and substantially spanning the prostatic urethra between, the bladder neck and external sphincter.

The utility model discloses a medical filterable small pathological tissue specimen bag, including specimen bag body and the top sealing press -fitting strip of setting in the inside of specimen bag body top end opening, the bottom sealing press -fitting strip of specimen bag body bottom end opening inside is provided with, the top sealing press -fitting strip and bottom sealing press -fitting strip and specimen bag body inner wall between close adhesion, and top sealing press -fitting strip and bottom sealing press -fitting strip and specimen bag body junction still adopt the encryption processing of sealing glue, the inside of specimen bag body is provided with filter screen, the filter screen is plastic dense mesh, the medical filterable small pathological tissue specimen bag of this new type is applicable to the collection pathological specimen when transurethral resection of prostate plasma cutting, laser enucleation, cystectomy, reduces the tissue collection time, reduces the pathological tissue loss risk, improves pathological tissue quality, increases the operation efficiency, solves the problem of time -consuming and labor -intensive when specimen collection, smaller tissue loss.

A transvaginal stimulation device incorporates various securing mechanisms configured to maintain secure engagement between the treatment portion of a transvaginal stimulation device and target tissue to increase the efficacy of therapeutic stimulation treatment. The device includes a concave portion configured with a stimulation array of electrodes, and the securing mechanism maximizes engagement between the stimulation array and the tissue to be treated. The device includes a flexible mechanism that increases the ability of the device to conform to the vaginal canal to maximize electrode contact. The securing mechanisms may be manually controlled or automatically controlled using predictive models trained using patient data. The predictive models may include machine learning models trained to dynamically modify device position and / or therapy in response to receipt of real-time information.

A transvaginal stimulation device incorporates various securing mechanisms configured to maintain secure engagement between the treatment portion of a transvaginal stimulation device and target tissue to increase the efficacy of therapeutic stimulation treatment. The device includes a concave portion configured with a stimulation array of electrodes, and the securing mechanism maximizes engagement between the stimulation array and the tissue to be treated. The device includes a flexible mechanism that increases the ability of the device to conform to the vaginal canal to maximize electrode contact. The securing mechanisms may be manually controlled or automatically controlled using predictive models trained using patient data. The predictive models may include machine learning models trained to dynamically modify device position and / or therapy in response to receipt of real-time information.

Provided are stable, concentrated, and palatable solutions suitable for sublingual and / or transurethral administration containing tadalafil, with or without other active ingredients to address comorbidities, in a liquid vehicle or solvent selected from propylene carbonate, 2-pyrrolidone, dimethyl isosorbide, dimethyl acetamide, n-methyl-2-pyrrolidone, ethanol, water, oleic acid, and isopropyl myristate. The solutions have low irritancy for sublingual tissues and a-are compatible with commercial atomizers. The invention is further directed to methods of treating male erectile dysfunction and / or comorbidities by administering an effective amount of the pharmaceutical formulations comprising tadalafil, with or without other active ingredients, to a patient in need of such treatments.

The invention discloses a targeted drug delivery biological hybrid micro-robot as well as a preparation method and application thereof. The micro-robot takes sperms as an active propulsion unit, and is constructed by combining PDA-DOX-FA nanoparticles through a coupling strategy; stable coupling of sperms and nanoparticles is realized through electrostatic adsorption, a biotin-streptavidin system or covalent binding. The micro-robot can enter the bladder through urethra perfusion, arrives at a tumor area depending on the autonomous propelling speed of sperms, realizes stable retention through folic acid targeted recognition and adhesion of neutrophil extracellular trapping nets (NETs), and realizes controllable release of adriamycin and deep penetration of tumors through a photothermal effect triggered by 808 nm near-infrared light. The problems of short retention, non-uniform distribution, insufficient permeation and the like of traditional bladder cancer perfusion treatment medicines are solved, the treatment efficiency and safety are remarkably improved, and the method is suitable for local precise treatment of bladder cancer.

The invention provides an implant for the simple and reliable treatment of a bladder neck. This is achieved by a removable implant in which a pressure-mediating structure is used to dilate the bladder neck. This structure exerts local pressure on the bladder neck tissue. The pressure-mediating structure can be connected to a retention element for handling. This retention element, which can be a wire, thread, or rod, serves to insert the implant or pressure-mediating structure through the urethra into the bladder neck and, if necessary, to remove the structure from the patient's body after the treatment is completed.

A delivery tube for image-assisted positioning an implantable expander in a prostatic urethra. An implantable biocompatible expander suitable for implantation into a urinary duct is resiliently deformable from a relaxed radially expanded orientation to a radially contracted orientation suitable for transluminal delivery through the urinary duct. The expander may be configured to exert an outward radial force against a wall of the urinary duct when in-situ within the urinary duct. In particular, the expander is suitable for treatment of benign prostatic hyperplasia and configured for implantation into the prostatic urethra between, and substantially spanning the prostatic urethra between, the bladder neck and external sphincter.

This invention discloses a transurethral prostate surgery robot system and its collaborative control method. The system includes an actuator carriage, a controller carriage, and an RCM positioning unit. The actuator carriage includes a surgical robotic arm, an ultrasonic robotic arm, a transrectal ultrasound probe, a binocular video recognition system, and a display. The RCM positioning unit, in conjunction with the binocular video recognition system, uses optical markers to determine the RCM1 point at the surgical entry point. The physiological opening corresponding to the insertion end of the transrectal ultrasound probe is determined by the control system as the RCM2 point. The control system establishes a screw coordinate system based on the RCM1 and RCM2 points, performs RCM-constrained kinematics solutions, and achieves collaborative control of the two robotic arms. This system can integrate and display endoscopic views and ultrasound-guided images, and combines force feedback and virtual fences to improve operational accuracy and safety. It is suitable for minimally invasive surgeries such as transurethral resection of the prostate (TURP) and laser enucleation.