The invention provides a product unique code full-automatic packaging production line. The product unique code full-automatic packaging production line comprises a product code mechanism, a bagging code mechanism and a boxing code mechanism; the product code mechanism comprises a material-loading sequencing device and a laser-machine code device; the bagging code mechanism comprises a bagging conveyor belt and a bagging machine; the boxing code mechanism comprises a boxing device, a carton conveyor belt and a second industrial code machine, wherein the boxing device is arranged at the rear endof the bagging machine, and the second industrial code machine is fixed on the side edge of the carton conveyor belt. According to the product unique code full-automatic packaging production line, products, product packaging bags and cartons are coded, the codes are correlated with one another, and unqualified products are removed through an omni-directional removing system, so that the quality of the packaged products is guaranteed; and the removed product information is fed back to a controller for information processing, so that the unique correlation of the product information is ensured.