The invention provides a door and window protective sleeve. The door and window protective sleeve comprises a door and window frame, wherein a protective sleeve main body is arranged at the splicing position of the door and window frame, the protective sleeve main body is L-shaped, a mounting hole is formed in the protective sleeve main body, a fixing device is arranged in the mounting hole, a chamfer is arranged at the bending position of the protective sleeve main body, the protective sleeve main body comprises a first side plate and a second side plate, the first side plate is connected with the second side plate through a connecting plate, a sealing wool top is arranged on the first side plate, and an adsorption strip is arranged on the connecting plate. The protective sleeve main bodycan be quickly sheathed at the splicing position of the door and window frame through a channel formed by the first side plate, the second side plate and the connecting plate, and the protective sleeve main body is fixedly connected with the door and window frame through the fixing device, so that the assembly operation of the protective sleeve is simple, the production efficiency is improved, the sealing wool top can achieve a good sealing effect, the resistance during the movement of the door and window frame is reduced, the stability of a door and window is ensured, the adsorption strip can eliminate excess collision force or supplement the insufficient force during closing, and secondary operation is avoided.