The invention relates to the technical field of etching, and discloses circuit board production equipment based on a vacuum etching technology. The equipment comprises a base, two clamping plates, anetching cylinder, a rotating motor, a turntable, a vacuum device and an etching device, and is characterized in that the bottom surface of the etching cylinder is in a hollow state, the clamping plates are inverted L-shaped bodies, and the two clamping plates are opposite to each other left and right; the surfaces, deviating from each other, of the two clamping plates are curved and are matched with the inner wall of the etching cylinder, the vacuum device and the etching device are both arranged on the etching cylinder, and through arrangement of the vacuum device, a vacuum effect is formed in the whole etching cylinder by utilizing a continuous air exhaust effect, so that dust and the like in the base are powerfully extracted, and the etching efficiency is improved. Therefore, dust in the base or on the circuit board before etching and smoke and impurities generated by chemical reaction in the etching process are removed, the cleanliness of the circuit board after etching is improved, the problem that the quality of the circuit board is reduced due to the fact that the smoke and the impurities such as the dust participate in the etching process is solved, and compared with an existing cleaning mechanism on an etching machine, the cleaning range is more comprehensive, and the cleaning force is stronger.