The invention discloses a device for conducting laser cladding treatment on plates and belongs to the technical field of industrial robots. The device comprises a lower cabinet, a cross-shaped electric cylinder, a rotating mechanism, a laser cladding mechanism, a visual system and an upper supporting frame. The cross-shaped electric cylinder comprises a horizontal electric cylinder body, a vertical electric cylinder body and a slide block. The rotating mechanism comprises a bottom plate, supporting posts, a third drive device, an expansion tightening sleeve, a workpiece holding disc and a workpiece holding box. The laser cladding mechanism comprises a horizontal-moving guide rail rack, a small sliding bearing, an upper flat panel, a hand wheel, a lead screw, an L-shaped support, a lower flat panel, a laser head, cushion plates, big sliding bearings and cylindrical linear guide rails. The visual system completes acquisition and processing of workpiece information. Laser cladding treatment for the plates is achieved through coordination of the cross-shaped electric cylinder, the rotating mechanism, the laser cladding mechanism and the drive device. The device is simple in structure, low in weight, high in efficiency and precision and automation degree, low in cost, and capable of being widely applied to various industrial sites.