The invention relates to an intelligent reduction system for a long bone fracture. In order to avoid a long bone fracture open reduction fixing operation and achieve precise, minimally invasive and intelligent fracture reduction fixing and even if remote treatment, according to the technical scheme, the intelligent reduction system comprises a perspective system, a computer control system and a reduction mechanical arm, wherein the computer control system is used for receiving images of the perspective system, and the reduction mechanical arm is controlled by the computer control system to perform corresponding actions. A five-shaft manipulator is arranged on the reduction mechanical arm, is driven by the reduction mechanical arm and enables the fracture portion to perform positive and negative bi-direction translation, tilt and rotation in the X coordinate axis, the Y coordinate axis and the Z coordinate axis. By the adoption of the technical scheme, a doctor will not be subjected to a great deal of radioactive irradiation in the perspective reduction process, increased wounds and pains, caused by long bone fracture open reduction, of a patient are avoided, and the purpose of precise, intelligent and minimally invasive closed reduction for the fracture is achieved.