The invention provides an integrated downhole operation tool based on a two-way slip hydraulic permanent packer. The working tool includes: a test valve, a pressure gauge holder, a liquid replacement valve, a plugging valve and a two-way slip hydraulic permanent packer. Wherein, the packer includes: an upper mandrel, a lower mandrel, an upper hydraulic outer cylinder, a lower hydraulic outer cylinder, a first shearing fixture, a second shearing fixture, a third shearing fixture, and From top to bottom, the upper slip, the upper cone, the rubber tube, the lower cone, the lower slip, the lock ring assembly, the double male nipple, and the annular piston sleeved on the lower mandrel are set on the upper mandrel in sequence. The upper end of the test valve can be connected to the upstream of the integrated downhole operation tool, the lower end of the test valve is connected to the upper end of the pressure gauge, the lower end of the pressure gauge is connected to the upper end of the replacement valve, and the lower end of the replacement valve is connected to the upper end of the plugging valve , the lower end of the plugging valve is connected with the two-way slip hydraulic permanent packer. The invention has the functions of oil testing and well completion and production at the same time.