The invention relates to the technical field of minimally invasive surgical instruments and particularly relates to a multi-shooting tissue clamp. The tissue clamp comprises a shell, sliding ring, a flexible pipe, at least two clamping mechanisms and an operation rod, wherein the sliding ring is connected with the shell in a sliding manner; the flexible pipe is fixed at one end of the shell and iscommunicated with the shell; the clamping mechanism is mounted in the flexible pipe and can be pushed out of the flexible pipe; two ends of the operation rod are respectively connected with the clamping mechanisms and the sliding ring; and at least two clamping mechanisms are distributed along the axial direction of the flexible pipe, the sliding ring slides to push the clamping mechanisms out ofthe flexible pipe through the operation rod, and when a tissue is clamped by virtue of the clamping mechanism located outside the flexible pipe, the operation rod is pulled to be separated from the clamping mechanism and is connected with the next clamping mechanism, and the next clamping mechanism can be pushed by the operation rod and can be used for separating the last clamping mechanism fromthe flexible pipe. According to the technical scheme, the surgical operation process is greatly simplified, the efficiency of a hemostasis surgery is effectively improved, the plugging number of timesduring the single surgery is reduced, the service life of a pincers channel is prolonged, and the equipment cost is lowered.