A method and apparatus for generation of signals with unpredictable 
transmission properties allowing physically secure, unscheduled and interference-resistant communication over 
machine-to-
machine (M2M) networks is claimed. A physical dwell structure comprising time slots and frequency channels is established, and a combination of unpredictable physical dwells, 
spread spectrum modulation formats employing unpredictable spreading vectors, and additional physical properties allowing unpredictable selection of intended receivers is described. These unpredictable 
transmission properties enable receivers employing blind detection and 
signal separation techniques to detect and extract transmissions intended for the receive, and excise transmissions not intended for the 
receiver, as part of the despreading procedure, and even if those transmissions are received at a much 
higher power level than the intended transmissions. The 
resultant system eliminates the ability for an 
adversary to predict and override M2M transmissions; allows reception of ad-hoc transmissions in dense environments without scheduling, CSMA / CA protocols, or feedback paths enabling scheduling, and allows macrodiverse reception of transmissions at networks of connected receivers, thereby providing additional efficiency and security improvements by exploiting the 
route diversity of the network.