26 results about "Human musculoskeletal system" patented technology

The invention provides a personalized man-machine coupling digital twinning model construction method and system, and relates to the technical field of digital twinning, and the method comprises the steps: constructing a man-machine coupling lower limb exoskeleton rehabilitation robot digital twinning model constructed for a target rehabilitation patient; the model is coupled with a rehabilitation patient musculoskeletal system digital twinborn model and a lower limb exoskeleton rehabilitation robot digital twinborn model. The initial rehabilitation parameters are input into the human-machine coupling lower limb exoskeleton rehabilitation robot digital twinborn model for simulation, and simulation physiological feature information of a key muscle group is obtained; and comparing the simulation physiological feature information with evaluation information from experts, and verifying the reliability and effectiveness of the theoretical method provided by the invention.

Disclosed are a method for creating a surgical training model, a surgical training model apparatus, a bone model, an article that emulates tissue of an animal musculoskeletal system, an article that emulates animal fat tissue, and an article that emulates animal skin tissue. One version of the method comprises placing a spinal vertebrae model in a cavity model that emulates an animal body cavity; forming a first layer on top of the vertebrae model, wherein the first layer emulates an animal muscle tissue; placing a second layer over the first layer, wherein the second layer emulates an animal fat tissue; and placing a third layer over the second layer, wherein the third layer emulates an animal skin tissue. The spinal vertebrae model can be 3D printed from a thermoplastic polymer and infiltrated with a foam into an interior space of the 3D printed spinal vertebrae model.

The present invention relates to: extracellular vesicles linked with pro-inflammatory cytokines; and mesenchymal stem cells treated with the extracellular vesicles and having improved anti-inflammatory activity. Treating mesenchymal stem cells with extracellular vesicles according to an aspect during the culturing thereof can improve the tissue regeneration and inflammation regulatory factor secretion ability of the mesenchymal stem cells, and thus the mesenchymal stem cells can be effectively used for alleviating nervous system and musculoskeletal inflammatory diseases, and pain associated therewith.

A new shape changing staple and instrument for the fixation of structures to include bone tissue and industrial materials. This new staple stores elastic mechanical energy to exert force on fixated structures to enhance their security and in bone affect its healing response. This staple once placed changes shape in response to geometric changes in the materials structure, including healing bone tissue. The staple is advanced over prior staples due to its: 1) method of operation, 2) high strength, 3) method of insertion, 4) compressive force temperature independence, 5) energy storing staple retention and delivery system, 6) compatibility with reusable or single use product configuration, 7) efficient and cost effective manufacturing methods, and 8) reduction in the steps required to place the device. In addition to the staple's industrial application an embodiment for use in the fixation of the musculoskeletal system is shown with staple, cartridge, and extrusion handle.

Kit to compensate for a misalignment and / or incorrect loading of a person's musculoskeletal system, with a foot cover (2) for one of the person's feet, wherein the foot cover (2) in the wearing state covers at least a section of the foot and / or completely surrounds or encloses the foot at least in sections, and with at least one support element (4) for supporting and / or lifting a foot section, wherein the foot cover (2) has at least three different predefined areas (5), wherein in the wearing state a support element (4) is detachably attached to a predefined area (5) or a plurality of support elements (4) are attached to different predefined areas (5).

The present invention relates to novel compounds having a histone deacetylase 6 (HDAC6) inhibitory activity, stereoisomers thereof or pharmaceutically acceptable salts thereof, a medicinal use thereof, and a method for preparing the same. The novel compounds according to the present invention, stereoisomers thereof or pharmaceutically acceptable salts thereof have the histone deacetylase 6 (HDAC6) inhibitory activity, and are effective in preventing or treating HDAC6-related diseases, comprising infectious diseases; neoplasm; endocrinopathy; nutritional and metabolic diseases; mental and behavioral disorders; neurological diseases; eye and ocular adnexal diseases; circulatory diseases; respiratory diseases; digestive diseases; skin and subcutaneous tissue diseases; musculoskeletal system and connective tissue diseases; and teratosis or deformities, or chromosomal aberration.

A system for generating a comestible plan to manage musculoskeletal system disorders is disclosed. The system comprises a computing device configured to receive an input comprising physiological data. Computing device may generate a physiological data classifier, Computing device may classify, using the physiological data classifier, the physiological data to a class of physiological data relating to musculoskeletal disorders. Computing device may extract a plurality of biological determinants of a disease state from the physiological data, wherein the plurality of biological determinants includes at least one biological determinant related to at least one disorder located in musculoskeletal system. Computing device may determine a biological determinant concentration. Computing device may identify a musculoskeletal system disorder based on the at least one biological determinant and the biological determinant concentration. Computing device may generate a holistic program as a function of a positive result for the musculoskeletal system disorder.

The invention relates to the field of medicine, and more particularly to neurology, traumatology, orthopaedics, immunology and therapy. The invention relates in general to medicine, and more particularly to manual therapy and orthopaedics, and is intended for diagnosing and correcting functional states of the spine and musculoskeletal system. The aim and technical result of the claimed invention is the use of manual therapy techniques to treat herniated discs of the lumbar spine. To achieve this aim, a method for treating herniated lumbar discs using manual techniques is proposed which includes mobilizing the vertebrae and intervertebral tissues of the lumbar spine in three planes, sagittal, frontal and horizontal, and realigning the vertebral bodies in the L3-L4 and L4-L5 segments, the method being characterized in that, in addition, the pelvis is gripped and then is realigned in a single procedure by rotating the sacrum and the iliac wings under ultrasound monitoring. The method according to claim 1 is characterized in that hernias having a minimum size of from 0.4 to 2.0 cm are treated.

According to the human body musculoskeletal system physiological age prediction method based on machine learning, 11 blood detection indexes closely related to a musculoskeletal system are collected in a targeted manner, and computer model modeling is performed on male and female data around musculoskeletal system health data; and constructing a computer model for predicting the physiological age of the human musculoskeletal systems of men and women to evaluate the physiological age of the human musculoskeletal systems of individuals with different genders. According to the human body musculoskeletal system physiological age prediction method based on machine learning, core data only uses data indexes related to a human body musculoskeletal system for modeling, so that the physiological age of the human body musculoskeletal system can be evaluated in a targeted manner; moreover, according to the human body musculoskeletal system physiological age prediction method based on machine learning, modeling is carried out on the male and the female based on the data difference of the male and the female genders, so that the prediction result is more accurate.

The invention relates to a system for monitoring patients (P1, P2 ... PN) after a procedure on a musculoskeletal system, comprising: • a plurality of patient-related sensors (SP1,1, SP1,2, ... SP1,M), • wherein a subset of the sensors determines movement parameters and a further subset of the sensors determines other medical parameters, • and a central unit (Z), • wherein the plurality of sensors and the central unit each contain devices for data exchange (I / O) with the aid of which sensor data can be transmitted to the central unit, • at least one selection unit (T) for displaying and selecting medically relevant parameters of the patient-related sensors, • wherein the central unit has Kl methods and algorithms that were previously trained using sensor parameters and with the aid of the selection unit,Based on a patient-specific preselection of the parameters to be considered, a score to be used in medicine is determined in relation to the course of rehabilitation of the measure, and a general assessment of the patient's condition is also carried out on the basis of other medical parameters, • Based on the score to be used in medicine and the general assessment of the condition, a recommendation for an adjustment and / or an intervention is given to a medical professional and / or the patient.

The invention relates to a method and a device for operating a controllable seating system of a vehicle seat (1), wherein the seating system comprises controllable seat elements (S1 to S4) and / or massage elements (M1 to M10) by means of a control unit (2) and a number of pressure sensors and / or force sensors (K1 to K10) integrated into the vehicle seat (1). According to the invention, it is provided that a pressure sensor and / or force sensor (K1 to K10) is assigned to each seat element (S1 to S4) and / or massage element (M1 to M10), wherein the resistance exerted on the seat elements (S1 to S4) and / or massage elements (M1 to M10) by the body of an occupant (3) on the vehicle seat (1) when adjusting them is determined on the basis of data acquired by the respective pressure sensor and / or force sensor (K1 to K10). - a resistance pattern is generated based on the determined data, - the resistance pattern is compared with a resistance pattern stored in the control unit (2) and based on an anatomical model, - in the event of a detected deviation between the generated resistance pattern and the resistance pattern based on the anatomical model, a distinction is made between a misalignment of the occupant's musculoskeletal system (3) and muscular tension, whereby - the seating elements (S1 to S4) and / or massage elements (M1 to M10) are optimized depending on the individual anatomy of the occupant (3).

A method for providing a user-customized service based on at least one of a musculoskeletal system or a nervous system comprises the steps of: receiving state information about a user; determining one or more musculoskeletal examination items on the basis of the received state information about the user; outputting the one or more determined musculoskeletal examination items; receiving, for each of the one or more output musculoskeletal examination items, one or more images including at least one of the user's posture or motion; receiving meta information about examination equipment for capturing the one or more images; and analyzing the user's state information, the one or more images, and the meta information by using a first machine learning model, and outputting a customized result for the user.

The present invention discloses a method for repositioning and navigating high-energy injuries of the lower limb skeleton. The method comprises establishing a dynamic biomechanical model of a robot and the musculoskeletal system and performing repositioning and navigation simulation, analyzing the motion and force relationship between the fracture fragments and the robot, planning a skeletal repositioning and navigation path, and recording the path as a basis for optimal path selection and a reference for model optimization design. Simulation is performed in conjunction with medical imaging and anatomical histological data to construct an optimal path planning cost function, determine the parameters for searching the repositioning and navigation path, and determine and fix the target of the optimal path algorithm. The present invention is the first to consider avoiding important soft tissues as a key factor in repositioning and fixing the path. It comprehensively considers the repositioning action mode, the longitudinal traction muscle force, the joint position, and other multi-information fusion decisions to optimize the planning path, thereby solving the problems of insufficient flexibility and the susceptibility to secondary injuries in the previous repositioning and navigation process of parallel robots.

The invention relates to a pharmaceutical composition, a method of treatment utilizing thereof, and a pharmaceutical composition for use in the treatment of disease of the musculoskeletal system, which, as an active ingredient, comprises autologous platelet-rich plasma; a local anesthetic selected from lignocaine, ropivacaine, bupivacaine, benzocaine, chloroprocaine; an anti-edematous compound selected from betamethasone, triamcinolone, methylprednisolone, triamcinolone, methylprednisolone acetate; hyaluronic acid; somatotropin and strophanthin; wherein the pharmaceutical composition is intended to be administered in an effective dose to the treated target site of the musculoskeletal system of a subject, which is a mammal, more preferably a human.

To provide a non-powered ergonomic magnetic heating garment, belonging to the field of medical and healthcare technology. [Solution] The garment includes a top and trousers, and the central opening of the top is provided with an elastic adjustment member to accommodate various body types. To apply magnetic thermotherapy to injured areas of the body's musculoskeletal system, heating pads and / or magnetic therapy pads can be detachably attached to the neck, shoulders, back, chest, abdomen, waist, upper arms, and forearms of the top, and heating pads and / or magnetic therapy pads can also be detachably attached to the thighs, lower legs, knees, and ankles of the trousers. Fixing components can be detachably attached to the neck, shoulders, back, chest, abdomen, waist, thighs, lower legs, knees, and ankles to provide mechanical support. The present invention designs a magnetic thermotherapy garment utilizing magnetic thermotherapy, and by applying magnetic thermotherapy interventions of different durations and intensities to injured tissue, the magnetic thermotherapy garment can provide effective mechanical support to local tissue, contributing to the reduction of local injury and the enhancement of therapeutic effects.

Compositions and methods comprising a CD40L-specific Tn3 scaffold are provided, as are methods for preventing and treating Sjögren's syndrome. Sjögren's syndrome (SS) is a systemic autoimmune disease characterized by chronic lymphocytic inflammation of exocrine glands, primarily the salivary and lacrimal glands, leading to loss of function and manifesting as excessive dryness. In addition, extraglandular manifestations have been described as multisystemic involvement affecting the musculoskeletal, pulmonary, renal, neurological, dermatological, gastrointestinal, hematological, hepatobiliary, or vascular systems, while fatigue is a particularly prominent comorbidity.

The present invention relates to a wearable protector with improved mounting force, and more specifically, comprises an upper body support portion made of a flexible material with a certain surface area and positioned on the user's back and waist, a pair of shoulder strap portions into which each of the user's arms is inserted to mount the upper body support portion on both shoulders, an upper body mounting portion for connecting the pair of shoulder strap portions to fix the upper body support portion to the upper body, a waist mounting portion for fixing the upper body support portion to the user's waist, and a lower body support portion in which the upper end is connected to the upper body support portion and the lower end is mounted on the user's lower body so as to straighten the user's bent upper body by elastic force. According to the present invention as described above, when the waist or upper body is bent to lift an object, the musculoskeletal system can be assisted so that the body can be easily straightened by elastic force, thereby preventing and minimizing safety accidents such as muscle pain, and the user's body temperature can be maintained at a temperature suitable for easy work, thereby improving work efficiency.

Disclosed are a method for creating a surgical training model, a surgical training model apparatus, a bone model, an article that emulates tissue of an animal musculoskeletal system, an article that emulates animal fat tissue, and an article that emulates animal skin tissue. One version of the method comprises placing a spinal vertebrae model in a cavity model that emulates an animal body cavity; forming a first layer on top of the vertebrae model, wherein the first layer emulates an animal muscle tissue; placing a second layer over the first layer, wherein the second layer emulates an animal fat tissue; and placing a third layer over the second layer, wherein the third layer emulates an animal skin tissue. The spinal vertebrae model can be 3D printed from a thermoplastic polymer and infiltrated with a foam into an interior space of the 3D printed spinal vertebrae model.

Based on combination therapy, we propose a cell therapy that can significantly enhance the therapeutic effect of treatment for cerebrovascular disease, ischemic heart disease, or traumatic cerebrospinal nerve injury in subjects compared to conventional methods. [Solution] A cell preparation containing microglia and / or monocytes, which have the ability to promote angiogenesis and axon extension, is administered to the subject. By repeatedly implementing a bidirectional biofeedback loop between the nervous system and the musculoskeletal system, the effect of improving the motor function of the subject's brain, nervous system, and muscular system is enhanced.

1. The name of the design product: medical magnetic resonance imaging device (1.5T MRI system). 2. The use of the design product: used for medical imaging system and diagnosis of nervous system disease, cardiovascular system, musculoskeletal system, digestive system, etc. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: perspective view.

A method for implementing a musculoskeletal disorder prediction model, performed by a musculoskeletal disorder prediction model implementation apparatus. The method includes: acquiring a user image which performs a pre-registered musculoskeletal test motion; extracting a feature point of a body part which performs the musculoskeletal test motion from the user image by using a motion recognition model implemented in advance; determining a range of motion ROM of a musculoskeletal system corresponding to the body part based on a movement trajectory of the extracted feature point of the body part; extracting a reference feature point of a pre-registered musculoskeletal normal range of motion image; comparing the movement trajectory of the extracted feature point of the body part and a movement trajectory of the reference feature point; and matching and storing a comparison result of the determined range of motion and the movement trajectory.

A measurement system comprising a measurement device and a computer. The measurement device is configured to measure a force, pressure, or load applied by the musculoskeletal system. The measurement device comprises an enclosure and a structure configured to fit within an opening in the enclosure. The enclosure is hermetically sealed housing electronic circuitry and at least one sensor. The structure is configured to couple to the musculoskeletal system. At least three sensors underlie and couple to the structure to measure a force, pressure, or load applied to a surface of the structure. The structure includes at least three anti-cantilevering structures. At least one of the three anti-cantilevering structures is configured to couple to the enclosure to limit canting of the structure when the musculoskeletal system couples to the surface of the structure outside a predetermined area.

To provide a system and method for providing a user-customized service based on at least one of a musculoskeletal system and a nervous system.SOLUTION: The method includes receiving state information of a user, determining one or more musculoskeletal examination items based on the received state information of the user, outputting the determined one or more musculoskeletal examination items, receiving one or more images including at least one of a posture or a motion of the user with respect to each of the output one or more musculoskeletal examination items, receiving meta information about an examination device that captures the one or more images, and performing, using a first machine learning model, the method includes analyzing state information, one or more images, and meta information of a user and outputting a customized result for the user.SELECTED DRAWING: Figure 15

Disclosed is a method for predicting a musculoskeletal disorder based on motion recognition, which is performed by a musculoskeletal disorder prediction apparatus. The method according to an exemplary embodiment may include: acquiring a user image including a motion of a musculoskeletal body part; identifying a body part motion corresponding to at least one of pre-registered musculoskeletal test motions in the user image by using a motion recognition model implemented in advance; determining a range of motion ROM of a musculoskeletal system which performs the body part motion based on the identified body part motion; and predicting a disorder risk of the musculoskeletal system based on the determined range of motion ROM by using a musculoskeletal disorder prediction model implemented in advance.

A system is disclosed herein for providing a kinetic assessment and preparation of a prosthetic joint comprising one or more prosthetic components. The system comprises a prosthetic component including sensors and circuitry configured to measure load, position of load on a curved surface, joint stability, range of motion, and impingement. In one embodiment, the system is for a cup and ball joint of a musculoskeletal system. The system further includes a computer having a display configured to graphical display quantitative measurement data to support rapid assimilation of the information. The kinetic assessment measures joint alignment under loading that will be similar to that of a final joint installation. The kinetic assessment can use trial or permanent prosthetic components. Furthermore, adjustments can be made to the applied load magnitude, position of load, and joint alignment by various means to fine-tune an installation.