The invention discloses an inertial control active suspension control system based on vehicle posture deviation, which comprises a vehicle body, an inertial measurement unit, a plurality of wheels, suspension servo actuating cylinders corresponding to the wheels one by one, and a displacement sensor, an electronic control unit and a servo controller group. When the number of wheels in the group ismore than 1, the upper cavity and the lower cavity of the suspension servo actuating cylinders of the wheels in the group are communicated respectively, so that the wheels in the group become a fulcrum for jointly supporting the vehicle body. Three groups of wheels form three fulcrums, the invention controls the posture of the vehicle body according to the principle that three points determine aplane, according to the changes of vertical displacement, pitch angle and roll angle of the vehicle center of mass, the expansion and contraction of each suspension servo actuator cylinder are controlled, so that the vehicle center of mass moves along a straight line or an arc line and the vehicle posture remains unchanged as far as possible, so that the vibration of the vehicle body is reduced, and the speed, the handling stability and the ride comfort of the vehicle are improved when the vehicle is traveling on the complex road surface.