The invention discloses a vehicle-mounted robot automatic operation control system which comprises a chassis and a carriage, the carriage is divided into an operation room and a robot cabin, a controller is arranged in the operation room, a robot, an automatic cleaning system and an automatic charging device are arranged in the robot cabin, and a hydraulic tail plate is installed on the rear portion of the carriage. Walking guide lines and laser radar detectors are uniformly distributed on a flat plate of the hydraulic tail plate and a bottom plate of the robot cabin; and a hydraulic sensor is arranged on the hydraulic tail plate. The hydraulic tail plate control system and the robot control system are combined, and the hydraulic tail plate is provided with the robot getting-on and getting-off guide line and the laser radar detector, so that automatic getting-on and getting-off of the robot are achieved. Meanwhile, an automatic rotating standing platform is arranged for the robot cleaning station, the upper portion cleaning mechanism, the side face cleaning mechanism and the bottom cleaning mechanism to comprehensively clean and sterilize the robot, automatic cleaning of the robot is achieved, a charging device is arranged for automatic butt joint charging, and full-automatic operation of the robot is achieved.