The invention relates to a distributed intelligent power supply and distribution system of a spacecraft, which is composed of a pulse battery, a functional battery, a plurality of intelligent power distribution centers in different regions, a main control device and a ground power source. The pulse battery is used for the power supply of the spacecraft, including initiating explosive devices, solenoid valves, equipment heating and motor power supply. The functional battery is used in the power supply of the spacecraft, including control, measurement and so on. Intelligent distribution centersare distributed by region on spacecraft and interconnected by standard buses. The intelligent distribution center receives the bus command from the main control equipment, completes the on-off controlof the power supply of each load on the spacecraft, and realizes the intelligent cut-off protection of short circuit and overcurrent of each load. The invention solves the shortcomings of the traditional spacecraft electromagnetic power supply and distribution system, such as large volume, heavy weight, low integration and intelligence, and has the characteristics of good digitalization, intelligence, integration and universality.