The invention discloses a power switch device pulse transformer isolation driving circuit. The power switch device pulse transformer isolation driving circuit comprises a primary-side circuit, a pulse transformer Tr and a secondary-side circuit, wherein the primary-side circuit comprises an NPN transistor Q2, a PNP transistor Q3 and a blocking capacitor C1, and the secondary-side circuit comprises a power switch device Q1, a driving resistor Rg, a gate discharge resistor Rs, a diode D1, a compensation capacitor C2, a voltage-regulator tube Z1 and a negative pressure holding capacitor C3. The power switch device pulse transformer isolation driving circuit of the invention can be applied to all switching converters such as a boost converter, a buck converter, a forward converter, a flyback converter, a half-bridge switching converter, a half-bridge converter, a full-bridge converter and a push-pull converter, and can effectively improve the reliability of the switching converters.