The invention discloses a probe cleaning and disinfecting device for ultrasonic medicine. The device comprises a flushing box body, a disinfecting box body, cleaning rollers, a liquid storage tank, rotating discs, a threaded rod, vibrating discs and ultraviolet lamps. The vibrating discs are arranged and can be driven to rotate through driving motors, and then vibrating contacts on the surfaces of the vibrating discs can rotate; through rotation of the vibrating contacts, the position of a vibrating plate can be moved; in the moving process of the vibrating plate, the lower ends of stretching rods at the lower end of the vibrating plate can drive extrusion blocks to slide in connecting blocks, and meanwhile, reset springs can be stretched; and when the vibrating contacts are separated from the vibrating plate, the extrusion blocks can be pulled back to initial positions through elastic force between the reset springs, and thus the resetting of the vibrating plate is realized. By means of the mode, a plurality of probes in a placement plate can be slightly shaken in the flushing process, then the positions of the probes can be moved, and therefore, the positions of the probes do not need to be manually adjusted for multiple times, and convenience is achieved.