The invention discloses an
RNA (Ribonucleic Acid) far homology detection method and
system based on
deep learning, and belongs to the field of
bioinformatics, an
RNA sequence
data set is divided into a plurality of sets and then a plurality of
training data sets containing far homology pairs are constructed, so that an
RNA far homology detection model is trained on the basis of each training
data set, a plurality of model variants are obtained, and the RNA far homology detection model is obtained. Performance evaluation is carried out based on the independent
test set to obtain a model with optimal performance; in the application stage, an
RNA sequence data set is converted into vector representation based on the model, a vector
database is constructed, after a to-be-detected sequence is received, the to-be-detected sequence is converted into vector representation based on the same mode, then the vector
database is retrieved, similar RNA sequences including far
homologous sequences are obtained, and an end-to-end
deep learning framework is achieved. And the
RNA sequence can be directly mapped to the
structural similarity without depending on the structural information of RNA, so that the
semantic gap between the sequence and the structure is effectively bridged.