The invention relates to a single-row 36-hole full-range harmonica with a
semitone alternate arrangement structure, and discloses a single-row full-range harmonica and a
semitone alternate arrangement structure thereof, a comb of the harmonica is provided with 36 sound holes, the sound holes are arranged in a
single row, and partition plates are arranged among the sound holes for separation; a reed plate is arranged between the cover plate and the frets, and blowing reeds 6 and suction reeds 7 are arranged at the positions, corresponding to the reed holes, of the reed plate and are arranged alternately. The single-row 36 sound holes and blowing / sucking reeds are alternately arranged in a semi-tone mode, the
pitch difference of the adjacent sound holes and the blowing / sucking reeds is semi-tone, 3 octaves (C-B2) are covered, key-free full-range coverage is achieved, 36 semi-tones can be covered, and the common range requirement of 88 keys of a
piano can be met; and the playing requirements of classical and popular music can be met. According to the full-range harmonica, a
semitone alternate arrangement structure is utilized, adjacent holes are semitone mutually, every other hole is full tone mutually, any modulation can be achieved, the playing complexity is simplified, meanwhile, musical scales are sequentially arranged from low to high, and the playing logic is clearer and convenient to grasp.