A combined
eyelid warming device,
resonance frequency generator,
coupling device, and tissue response sensor are disclosed in the field of use in dry eye treatment. These combined devices are used to ensure that the entire
eyelid surface and periorbital structures receive defined therapeutic warmth and appropriately tuned
harmonic resonance frequency for a required period of time to stimulate flow from the Meibomian glands. The combined elements of the invention include an easily moldable heating disc, targeted formulation of the heating material, miniaturized resonant frequency vibrating generator combined with a properly designed reusable
mask, to ensure precise location of the heat. Vibration may be delivered continuously or intermittently, and may be delivered according to one or more patterns. A
chemical sensor is included to characterize flow as vibration is varied. The
external energy source allows for circuitry in the external
power module to act as a sweep range device, targeting the specific optimally tuned point or sweep frequency the individual patients body reacts to during initial use. The initial testing device supplied to the Doctor for treatment would include sensing elements to determine the optimal
harmonic resonance frequency. Once the frequency is defined, the patient would receive a kit with custom
harmonic resonant frequency vibrating generators set to their optimum parameters. This configuration would be amenable to both
single use and reusable heater approaches.