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41results about How to "Reduce contact toxicity" patented technology

Preparation of avermectin medicament sustained-release nano microsphere preparations and uses thereof

The invention relates to a process for preparing avermectin and derivant dimethylamino avermectin, ivermectin, and doramectin slow release nanometer micro-balloon preparation. The technical procedures comprise suspending the suspending solution of 1%-40% unequal avermectin-type medicine, 0%-4% divinylbenzene (cross linking agent), (metyl group) methyl acrylate of 1% BPO (initiating agent) or solvent of methacrylic acid glycidyl ester in an aqueous phase of 40 DEG C with 1% sodium dodecyl benzene sulfonate and 0.5% gelatine or 0.5% PVA (the size ratio of an oil phase and the aqueous phase is 1:3) in a three-mouth bottle with an agitator, a reflux condensing tube and a thermometer, adding numerous ml of 0.5% methylene blue, regulating ultrasonic homogenization power, heating-up to 61 DEG C at 5 DEG C/10mins after the grain size is even, aggregating for two hours, heating-up to 85 DEG C with the same speed, aggregating for 8 hours and preparing 50nm-100nm avermectin-type medicinal nanometer micro-balloon preparation with different medicine-loading amount, and the packaging and loading rate reaches more than 91%. The invention solves the problem of long-acting controlled release of biological medicament, reduces the toxic and side effect simultaneously, improves the biological availability, reduces the cost and is friendly to the environment.
Owner:INST OF PLANT PROTECTION CHINESE ACAD OF AGRI SCI

Chenopodium ambrosioides volatile oil microcapsule and preparation method thereof

The invention discloses a chenopodium ambrosioides volatile oil microcapsule and a preparation method thereof and solves the problem that a conventional chemical bactericide is short in lasting period. A core material of the chenopodium ambrosioides volatile oil microcapsule is chenopodium ambrosioides volatile oil; a wall material is beta-cyclodextrin; the volume-weight ratio of the chenopodium ambrosioides volatile oil to the beta-cyclodextrin is 1 to (6-10). The preparation method comprises the steps of heating distilled water, adding 9-15 percent of the beta-cyclodextrin into the distilled water for dissolving the beta-cyclodextrin, stirring at a constant speed to obtain a beta-cyclodextrin aqueous solution, dissolving the chenopodium ambrosioides volatile oil through absolute ethyl alcohol according to the volume ratio of the chenopodium ambrosioides volatile oil to the absolute ethyl alcohol of 1 to (15-30) to obtain a chenopodium ambrosioides volatile oil and ethyl alcohol solution, gradually dropwise adding the chenopodium ambrosioides volatile oil and ethyl alcohol solution into the beta-cyclodextrin aqueous solution, stirring to obtain a mixed solution, putting the mixed solution into a refrigerator after the mixed solution is cooled, stewing the mixed solution, performing vacuum filtration, and drying the mixed solution until the weight is constant. The chenopodium ambrosioides volatile oil microcapsule has a good packaging effect, has the characteristics of being low in release speed, capable of prolonging of lasting period and safe to human and livestock and has small influence on the environment and non-target organisms.
Owner:XINYANG AGRI & FORESTRY UNIV

Micro-capsule suspending agent containing thiamethoxam and carbosulfan and preparation method of micro-capsule suspending agent

The invention relates to the technical field of crop pesticides, in particular to a micro-capsule suspending agent containing thiamethoxam and carbosulfan and a preparation method of the micro-capsule suspending agent. The micro-capsule suspending agent comprises an effective component and an auxiliary material, wherein the effective component comprises the following raw materials in percentage by weight: 1%-20% of thiamethoxam and 5%-30% of carbosulfan; the auxiliary material comprises the following raw materials in percentage by weight: 5%-30% of a capsule wall material, 5%-20% of a solvent, 0-3% of a synergist, 1%-15% of an emulsifier, 0.5%-10% of a suspending agent, 0-10% of a dispersing agent, 0-10% of an antifoaming agent and the balance of water; and the mass of the effective component accounts for 10%-45% of that of the mixed preparation. The suspended rate of the carbosulfan and thiamethoxam micro-capsule suspending agent is greater than or equal to 90%; meanwhile, the micro-capsule suspending agent has the advantages of low pesticide toxicity, long lasting time, high insecticidal control effect, simple preparation technology and the like; rice thrips of rice, underground pests of peanut and aphids of wheat paddock can be effectively prevented and controlled; and the yield of crops is increased.
Owner:ZHEJIANG TIANYI AGRI CHEM IND CO LTD

Synergystic pleocidin microsphere suspending agent and preparation method thereof

The invention discloses a synergystic pleocidin microsphere suspending agent and a preparation method thereof. Pleocidin synergystic microspheres are prepared by taking pleocidin and piperonyl butoxide as core materials and taking biodegradable material polylactic acid as a wall material, and then the pleocidin synergystic microspheres are mixed with a wetting dispersant, aluminum-magnesium silicate being as a thickening agent, ethylene glycol being as an anti-freezing agent, an organic silicon defoamer and water so as to prepare the synergystic pleocidin microsphere suspending agent. According to the synergystic pleocidin microsphere suspending agent and the preparation method thereof, the disadvantages in the prior art are overcome, and higher biological activity can be achieved only by needing the low content of the prepared synergystic pleocidin microsphere suspending agent, and thus multiple problems in production application caused by low contents of effective components of the microsphere suspending agent are solved. The synergystic pleocidin microsphere suspending agent disclosed by the invention has a wide prevention and cure spectrum, is high in pesticide effect, high in stability, low in environmental pollution, long in lasting period, low in prevention and cure cost, and accords with the requirement on pollution-free agricultural production.
Owner:FUJIAN AGRI & FORESTRY UNIV

Pyraclostrobin/Isoprothiolane microcapsule suspension, preparation method therefor and application of Pyraclostrobin/Isoprothiolane microcapsule suspension

The invention discloses a Pyraclostrobin / Isoprothiolane microcapsule suspension, a preparation method therefor and an application of the Pyraclostrobin / Isoprothiolane microcapsule suspension. The microcapsule suspension is prepared from the following ingredients in percentage by weight: 2.5% to 5% of Pyraclostrobin, 10% to 21% of Isoprothiolane, 3% to 10% of capsule-core solvent, 15% to 25% of capsule wall material, 3% to 7.5% of emulsifier, 3.4% to 4.7% of auxiliaries and the balance of water. Compared with the prior art, the microcapsule suspension has the advantages that the microcapsule suspension is prepared from Pyraclostrobin and Isoprothiolane crude pesticides through compounding and microcapsulation technologies, and the two kinds of pesticide ingredients are encapsulated in non-toxic capsule membranes, so that the contact toxicity of pesticide products can be lowered, and the stability of effective ingredients is further improved greatly; in addition, the effective control time of the products can be prolonged obviously, so that the repeated consumption of pesticides can be effectively avoided, and the pollution to environments is alleviated; and the conventional chemical raw materials are used, so that the comprehensive cost is low, the microcapsule suspension is in line with the direction of development of pesticide preparations, and the application prospect is relatively extensive.
Owner:江苏省苏科农化有限责任公司
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