The invention discloses surgical instrument disinfection equipment for general surgery department. The equipment is structurally provided with a base, a disinfection box body, a control box, a visible opening and a door cover, the disinfection box body is fixedly installed above the base, the control box is located above the disinfection box body and matched with the disinfection box body, the visible opening and the door cover are of an integrated structure and located at the middle end of the integrated structure, and the door cover is movably connected to the front end of the disinfection box body. A tray rod frame, a movable body and a variable ball generate interaction force, so that a folded plate is laterally opened, an elastic block is pressed, the elastic force of an air cushion and an air hole of the air cushion are convenient to press and sink, a tough block is pushed, the internal space of the air pressure cavity is changed, the air pressure is changed to act on a concentric-square-shaped groove, and rolling balls are subjected to blowing force generated by the elastic block, so that the rolling balls can roll back and forth, and react on the folding plates, the folding plates can swing and fold circularly, flexible contact between the variable balls and the tray rod frame is facilitated, and hard friction between the tray rod frame and the side end edge of a clamping rail is buffered.