The invention discloses an automatic driving system based on enhanced learning and multi-sensor fusion. The system comprises a perception system, a control system and an execution system. The perception system high-efficiently processes a laser radar, a camera and a GPS navigator through a deep learning network so as to realize real time identification and understanding of vehicles, pedestrians, lane lines, traffic signs and signal lamps surrounding a running vehicle. Through an enhanced learning technology, the laser radar and a panorama image are matched and fused so as to form a real-time three-dimensional streetscape map and determination of a driving area. The GPS navigator is combined to realize real-time navigation. The control system adopts an enhanced learning network to process information collected by the perception system, and the people, vehicles and objects of the surrounding vehicles are predicted. According to vehicle body state data, the records of driver actions are paired, a current optimal action selection is made, and the execution system is used to complete execution motion. In the invention, laser radar data and a video are fused, and driving area identification and destination path optimal programming are performed.