4 results about "Connective Tissue Disorder" patented technology

To provide pharmaceutical compositions for treating joint or connective tissue diseases, compositions for cartilage regeneration, or pharmaceutical compositions for treating inflammatory diseases.SOLUTION: Disclosed is a composition for preventing or treating a joint disease or connective tissue disease containing dextran, poloxamer or a mixture thereof as the effective ingredients.EFFECT: The composition of the invention stays in the joint or connective tissue for a long time due to the shock-absorbing effect, coating effect or anti-inflammation effect, and relieves the shock, covers a damaged portion in a specific manner thereto, or reduces inflammation of an adhered portion. Thus, the composition may be effectively used for the treatment of the joint or connective tissue disease, or for the cartilage regeneration.SELECTED DRAWING: Figure 5

The present invention relates to compositions and methods for the treatment of vascular Ellis-Dalos Syndrome and related connective tissue disorders. The invention also relates to a pharmaceutical composition and a kit for treating vasculopathy. The methods, compositions, and kits are capable of reducing the activity level of protein kinase C (PCK).

Embodiments of the instant disclosure relate to an in vitro system for generating 3D skin equivalent, compositions, and methods for modeling and analyzing potential therapeutic treatments of Ehlers-Danlos Syndrome (EDS), including personalized therapies and regimens. In certain embodiments, the in vitro system can be utilized to facilitate diagnosis, drug discovery, investigation of disease mechanisms, and treatment of EDS and other connective tissue diseases. In certain embodiments, compositions, and methods for making and using matrix metalloproteinase 9 (MMP-9) inhibitors are disclosed to treat EDS. In some embodiments, a subject has hypermobility type EDS (hEDS).

The application belongs to the technical field of medical devices, and particularly relates to a nested loosing needle device for injectable medicine, which comprises an injection structure, an injection needle body and a loosing needle body. The injection needle body is arranged on the port of the injection structure and used for puncturing the skin and injecting medicine. The loosing needle body has an inner through hole and is used for being sleeved on the outer periphery of the injection needle body to realize the switching between the two states of the exposed injection needle body and the retracted loosing needle body. One end of the loosing needle body is smoothly connected with the injection needle body and used for puncturing the skin. The composite sleeve design realizes the loosing and medicine injection functions of the needle device, significantly reduces the operation times, reduces the pain of patients, and improves the treatment efficiency and safety for complex diseases such as connective tissue diseases, bone joint diseases and soft tissue diseases. The design fills the blank of the multifunctional needle device in the prior art and has significant clinical application value.