The invention relates to a special fertilizer, specifically to a special fertilizer with rich selenium for grape. The fertilizer is prepared by comprising the following steps: crushing straws, then carrying out uniform mixing with wet chicken manure, corn flour and wood sawdust, and then adding rice-washing water, biological enzyme and yeast, carrying out uniform mixing, then carrying out sealing for fermentation, after fermentation, adding nitrogen fertilizer, phosphate fertilizer, potash fertilizer, chitin, selenium fertilizer and a soil conditioner, then continuously carrying out seeling for fermentation, after fermentation, and finally adding oleander liquid and carrying out uniform mixing so as to obtain the special fertilizer with rich selenium for the grape. The prepared fertilizer of the invention contains a variety of nutrients, contains a plurality of nutritional elements like nitrogen, phosphorus and potassium, is rich in more than 20 crop-needed quality elements like amino acid, humic acid, calcium, sulfur, zinc, iron and boron, exerts effects on regulating soil and balancing nutrients and is a novel highly-effective green fertilizer with full nutriention; selected pure raw materials with high quality are rich in soil-loosening and water-holding factors, so soil becomes looser; a variety of nutrients are added, so health of the grape is further protected; and natural mineral substances and plant growth substances are added, so fertility is more durable, resistance ability of plant body is effectively regulated, diseases are alleviated, and output of the grape is increased.