63 results about "Virus transmission" patented technology

The invention is applicable to the technical field of virus detection, and provides a norovirus detection kit based on a photo-thermal isothermal amplification technology and a detection method, the norovirus detection kit comprises a nucleic acid amplification chamber, the nucleic acid amplification chamber is provided with reaction micropores for nucleic acid amplification; an RT-PRA system, a CRISPR-cas12a system, a blank control and a positive control are placed in the reaction micropore, the RT-PRA system comprises RT-PRA solutions R1-R5, and the CRISPR-cas12a system comprises CRISPR-Cas12a solutions C1-C3; and the photo-thermal film covers the nucleic acid amplification chamber and is used for converting sunlight into heat energy and radiating the heat energy to liquid in the reaction micropores so as to provide reaction temperature for nucleic acid amplification. According to the invention, the portable, rapid and accurate detection of norovirus infection can be realized, the detection cost can be effectively reduced, the application scene is wide, workers can be helped to deduce the virus transmission path, and key support is provided for investigation and analysis of norovirus epidemic situations.

The application discloses a disease transmission link prediction method and system based on a dynamic hypergraph neural network, aiming to comprehensively depict virus transmission paths and risk levels from multiple dimensions. First, data is collected from a gene database, mobile device logs and clinical texts, virus variation characteristics, population contact relationships and symptom semantic information are extracted respectively, and a dynamic hypergraph that integrates virus strain nodes, individual nodes and regional nodes is constructed. The hyperedge is defined according to molecular similarity, space-time contact and semantic overlap, and the weight is dynamically adjusted according to the transmission intensity of the infectious disease. A multi-modal hypergraph neural network with variation perception is introduced to jointly model and adaptively fuse multiple types of hyperedges and multi-scale features, output node propagation embedding vectors and predict potential transmission chains, perform prevention and control responses, and realize real-time deployment and feedback loop in an edge-cloud collaborative manner, ensuring efficient and accurate infectious disease transmission modeling and intervention control while ensuring data privacy.

The invention discloses a disease transmission link prediction method and system based on a dynamic hypergraph neural network, and aims to comprehensively describe a virus transmission path and a risk level from multiple dimensions. The method comprises the following steps: firstly, collecting data from a gene database, a mobile equipment log and a clinical text, respectively extracting virus variation characteristics, a crowd contact relationship and symptom semantic information, and constructing a dynamic hypergraph fusing virus strain nodes, individual nodes and region nodes; the hyperedge is defined according to molecular similarity, space-time contact and semantic overlap, and the weight is dynamically adjusted along with the infectious disease transmission intensity. A multi-modal hypergraph neural network of variation perception is introduced, joint modeling and adaptive fusion are performed on multi-type hyperedge and multi-scale features, a node propagation embedded vector is output, a potential propagation chain is predicted, prevention and control response is executed, and real-time deployment and feedback closed loop are realized in an edge-cloud cooperation mode. And efficient and accurate infectious disease transmission modeling and intervention control are completed on the premise of ensuring data privacy.

This invention discloses a purifying fan, comprising a base, a fan housing, an impeller, a motor, and a purification component. The fan housing has an air chamber and is equipped with an air inlet and an air outlet, both communicating with the air chamber. The base is connected to the fan housing by a fixing member. The motor is mounted on the base, and the impeller is placed in the air chamber. The motor is connected to the impeller via a rotating shaft to drive the impeller to rotate. The purification component includes a purification shell, an ion generator, and an ion purification element. The purification shell is located on the side near the air inlet and has a purification chamber. The ion purification element is located in the purification chamber, and the ion generator is electrically connected to the ion purification element. The purification shell is equipped with an air collection port and an air guide port communicating with the purification chamber, and the air guide port is connected to the air inlet. This device not only functions as a fan but also purifies indoor air, reducing dust and microorganisms in the air and lowering the risk of virus transmission.

The application provides a dengue virus protection and mosquito vector control antigen composition and application thereof. The antigen composition comprises a combination of dengue virus type 1-4 envelope protein domain III polypeptide and Aedes aegypti midgut mucin AaMuc1 antigen polypeptide; the amino acid sequences of the dengue virus type 1-4 envelope protein domain III polypeptide are respectively shown as SEQ ID NO. 1, SEQ ID NO. 2, SEQ ID NO. 3 and SEQ ID NO. 4; and the amino acid sequence of the Aedes aegypti midgut mucin AaMuc1 antigen polypeptide is shown as SEQ ID NO. 5. The prepared vaccine can induce the body to produce neutralizing antibodies against dengue virus type 1-4, achieve the protection of human body from dengue virus infection, induce the production of active antibodies targeting Aedes aegypti midgut mucin 1, inhibit and kill the dengue virus transmission vector Aedes aegypti, and achieve the dual prevention and control of dengue fever from two dimensions of infection prevention and transmission interruption.

The utility model relates to an endoscope pipeline brush which comprises a shell, a rotating shaft and a pliers pipeline brush. A cavity is formed in the shell, an extending hole is formed in one side of the shell, the rotating shaft is arranged in the cavity and rotationally connected between the two inner side walls of the shell, one end of a brush rod of the pliers pipeline brush is fixedly connected with the rotating shaft, and the other end of the brush rod is wound by the rotating shaft, extends out of the extending hole and is connected with a brush head of the pliers pipeline brush. According to the technical scheme, the brush rod of the plier pipeline brush can be wound around the rotating shaft in the shell, occupied storage space is reduced, the plier pipeline brush can be pulled out by a specified length to be used according to use requirements, operation flexibility is improved, and the situation that a traditional plier pipeline brush is too long and not easy to operate is avoided; the brush rod part which does not extend out can be kept clean, virus transmission is reduced, and the cross infection risk is reduced.

This utility model discloses a positive and negative pressure switching fresh air system, comprising: an intake fan connected to an air distribution box via pipes, the air distribution box connected to the intake valves of each room via pipes and silencers; a return fan connected to a collection box via pipes, the collection box connected to the return air valves of each room via pipes; when the intake fan is turned on and all the intake and return air valves of all rooms are fully open, all rooms are in a positive pressure state; when the return fan is turned on and all the intake and return air valves of all rooms are fully open, the return air volume is greater than the intake air volume, and all rooms are in a negative pressure state; when both the intake and return air fans are fully open, if room 1 opens its intake valve and closes its return air valve, room 1 is in a positive pressure state; if room 2 opens its return air valve and closes its intake valve, room 2 is in a negative pressure state; positive pressure rooms prevent virus intrusion, and negative pressure rooms prevent virus spillover; infected individuals live in negative pressure rooms, and uninfected individuals live in positive pressure rooms, which can prevent cross-infection among family members and is very suitable for the current virus transmission situation.

A viral transmission barrier suitable for group settings encountered in places such as school or workplace cafeterias. The article aspect is a viral transmission barrier for tables with a height and a top surface with a length, a width, and a perimeter configured to accommodate a group of at least two people that may be strangers sitting in chairs at the perimeter and each having a section of table perimeter before them. Specifically, the article aspect comprises four elements, a multitude of vertical side panels, at least one neighboring vertical panel, a releasably attaching element, and a horizontal ceiling panel. The method aspect is aa method of using a viral transmission barrier to prevent the transmission of airborne viral particles from an infected person to others of a group of at least two people that may include strangers and are sitting in chairs at a table with a perimeter and each having at least 24 in, (61 cm) of perimeter before them at a function where masks are not worn. Specifically, the method comprises five steps.

The invention provides a fluorescent quantitative PCR (polymerase chain reaction) detection primer, a kit and a method for a novel variable chalmavirus VP gene, and belongs to the technical field of virus detection. A specific primer is designed and synthesized according to a conserved sequence of a VP gene of the novel variant chalmavirus, a recombinant plasmid is constructed, then the recombinant plasmid is used as a standard substance to establish a standard curve, a real-time fluorescent quantitative PCR detection system aiming at the novel variant chalmavirus is constructed, and specific detection of the novel variant chalmavirus is realized. The detection method can be used for quantitatively detecting the novel variant chalmavirus in the to-be-detected sample, and has the characteristics of high speed, high sensitivity, strong specificity and the like; the method provides a key technical support for molecular epidemiological investigation of the Sepamavirus in animal populations, is helpful for realizing early screening of infected individuals and timely blocking of virus transmission, and has important practical significance for guaranteeing population health and maintaining high mountain ecosystem stability.

The utility model discloses an automatic cleaning laying hen breeding cage, including hencoop, excrement cleaning mechanism, crib cleaning mechanism and control panel, control panel is installed on one side of hencoop, the hencoop is formed by connecting cage body and frame, excrement cleaning mechanism includes collecting tank, screw transmission group, support seat, cleaning box and cleaning roller, and the cleaning roller is connected with the collecting tank. The feeding trough cleaning mechanism comprises a flow guide pipe and a scraping plate. The chicken coop is provided with the excrement cleaning mechanism, the feeding trough cleaning mechanism and the control panel, excrement generated by laying hen breeding can be automatically collected, excrement adhering to the bottom face of the chicken coop can be cleaned, peculiar smells and virus spreading in a breeding house are reduced, meanwhile, residual feed in the feeding trough is cleaned, and the breeding efficiency is improved. Bacteria breeding in the feeding trough is avoided, a good feeding environment is provided for laying hens, and the egg laying yield is increased.

The application discloses a tomato Soly04g076730 Gene or its encoded protein is applied to resisting plant geminivirus. Soly04g076730 The gene is transiently expressed or stably genetically transformed in a plant leaf. When a virus invades the plant, the plant immune response is rapidly induced, and the disease resistance of the plant is improved. The Soly04g076730 protein is a secretory protein. The plant immune ability can be improved by expressing or externally applying the protein in the plant, and the virus transmission and replication can be effectively inhibited.

This utility model discloses an elevator call device based on Time-of-Flight (ToF) technology, belonging to the field of elevator control equipment technology. It includes a housing with a sensor window extending through its front end and a projection window extending through its front end near the upper edge. This utility model, through the cooperation of a projection display module and a ToF sensor module, fundamentally eliminates direct contact between the user and the device surface using non-contact ToF technology. Compared to traditional contact-based elevator call devices, it effectively reduces the transmission routes of bacteria and viruses, significantly lowering the risk of cross-infection between patients. In places with high population mobility, it provides users with a safer and healthier elevator environment, meeting the growing demand for public health and safety.

The utility model provides an epidemic disease prevention and control device, which relates to the technical field of epidemic disease prevention and control and comprises a support structure, the support structure is composed of a stabilizing plate and a stabilizing frame, a rotating shaft is mounted at the bottom of the stabilizing plate, two rollers are mounted on two sides of the rotating shaft respectively, and a storage is mounted between the stabilizing plate and the stabilizing frame. Through the unique mechanical structure design, automatic liquid spraying operation is achieved, when the pushing device enables the idler wheel to drive the rotating shaft to rotate, through a series of transmission cooperation such as bevel gear transmission, a cam mechanism and gear meshing, the spraying head can be automatically driven to swing in a reciprocating mode and spray prevention and control liquid, and the spraying efficiency is improved. Compared with traditional manually-operated spraying equipment, the spraying efficiency is greatly improved, the human input is reduced, comprehensive spraying can be completed in a shorter time, the efficiency of epidemic disease prevention and control work is effectively improved, and the virus spreading risk is reduced in time.

The invention relates to the technical field of infectious disease prediction, in particular to an infectious disease transmission risk prediction method and system based on big data analysis, and the method comprises the steps: firstly collecting multi-source heterogeneous data of population flow, environmental meteorology, historical epidemic situation, social media and public health resources, and then carrying out the cleaning, fusion and space-time alignment of the data, constructing a standardized database, training a dynamic propagation model based on machine learning, iteratively optimizing parameters by combining an SEIR improved model and real-time data, and finally outputting a regional risk level prediction result and a visual early warning map; according to the method, the multi-source heterogeneous data are fused, and the dynamic machine learning model is used for real-time analysis, so that complex influence factors of virus transmission can be more comprehensively captured, prediction deviation caused by single data or update delay in a traditional method is remarkably reduced, the risk early warning precision is improved, and the risk early warning efficiency is improved. And minute-level data processing and risk level updating are realized.

The invention relates to an air purifier control method and device, an air purifier, a computer readable storage medium and a computer program product. Early warning information and air quality information of the environment where the air purifier is located are obtained firstly. And under the condition that the early warning information is obtained, the air purifier is controlled to enter the first operation mode, all the purification units in the air purifier are triggered to operate, so that the air purification and disinfection effects are achieved to the maximum extent, emergency events can be quickly responded, the concentration of pathogens in air is reduced, the virus spreading risk is reduced, and the safety of the indoor environment is improved. And under the condition that the early warning information is not obtained, the target operation mode of the air purifier is determined according to the air quality information, the purification unit corresponding to the target operation mode is started to operate, that is, the corresponding purification unit is operated according to the actual indoor air quality requirement, the purification efficiency is optimized, energy consumption and equipment abrasion are reduced, and the service life of the air purifier is prolonged. And the service life of the air purifier is prolonged.

The utility model discloses an excrement and trough cleaning and disinfecting device for a laying hen farm, which comprises an excrement cleaning and disinfecting unit, a trough cleaning and disinfecting unit and a control panel, and the excrement cleaning and disinfecting unit comprises a support frame, a conveying belt, a cleaning box, a cleaning box, a disinfecting box and a drying box, the feeding trough cleaning and disinfecting unit comprises an electric sliding rail, a feeding trough scraping plate, a flushing and disinfecting pipe and a residue discharging pipe, and all electric control components in the excrement cleaning and disinfecting unit and the feeding trough cleaning and disinfecting unit are connected and controlled through wires and a control panel; according to the utility model, the manure cleaning and disinfecting unit, the trough cleaning and disinfecting unit and the control panel are arranged on the coop for combined use, so that manure generated by laying hen breeding can be collected and treated, and then the conveying belt for conveying the manure is disinfected to reduce peculiar smell and virus transmission in a breeding house; in addition, the feeding trough of the coop can be cleaned and disinfected, bacteria breeding in the feeding trough is avoided, a good feeding environment is provided for laying hens, and the egg laying yield is increased.

Device for the preventive blocking of neurotropic viruses in the peripheral nervous system, comprising a biochemical injection system for the localized release of a neurospecific binding molecule, a detection unit for the identification of viral particles in neuromuscular tissue, and a receptor bait structure for binding viral glycoproteins with affinity for neuronal receptors, characterized in that the device prevents retrograde axonal viral transmission without permanently impairing the conductivity of the nerve tissue.

The invention belongs to the technical field of biology, and particularly relates to a screening method of a small molecule compound for inhibiting insect-borne diseases and related application. In order to solve the problem that crop production is seriously harmed due to efficient aphid virus transmission, starting from the aphid feeding and virus obtaining process, a virtual screening-molecular docking method is adopted, Chinese gall bodies interacting with aphid colloidal salivary protein sheath protein are screened out for tanning, the Chinese gall bodies are used for tanning, viruses attached to the tip of an aphid mouth needle are reduced, and the aphid yield is improved. And the transmission efficiency of the virus is reduced.

The invention relates to the field of bioengineering, in particular to a recombinant collagen which is characterized by comprising one or more of the following characteristics: a, an amino acid sequence of the collagen is shown as any one of SEQ ID NO.1-4; and b. A, the collagen is added, substituted or deleted with one or more amino acids, and the protein has collagen activity. The recombinant collagen prepared by utilizing a genetic engineering technology has the remarkable advantages of stable quality, no virus transmission risk and the like, and has a good application prospect in the field of medical materials.

The application discloses a network virus propagation prediction and defense method and system, and belongs to the technical field of network security. The method constructs a dynamic infection state graph dataset indexed by time, each time step containing a node security attribute feature matrix and an infection state sequence; a spatial feature matrix is extracted through a graph attention network, and a global time feature matrix is extracted through a Transformer encoder; the global time feature is used as a query vector, and the spatial feature is used as a key-value pair, which are weighted and aggregated through a cross-attention mechanism to obtain a fusion feature matrix, and an infection state prediction result is mapped and output; the security attributes and topological context features of high-risk nodes in the prediction result are extracted and mapped into query vectors, enhanced knowledge is retrieved from an external knowledge base based on the query vectors, prediction information, security attributes, topological contexts and enhanced knowledge are input into a large language model to generate an active defense strategy, and an automatic closed loop from virus propagation prediction to active defense is realized.

This invention discloses the application of an endogenous Bunyavirus element LsBuEVE and its dsRNA from the planthopper in blocking the transmission of rice viruses. The LsBuEVE genome contains the nucleotide sequence shown in SEQ ID NO.1, and its corresponding transcript contains a complete open reading frame, the nucleotide sequence of which is shown in SEQ ID NO.2, and the encoded amino acid sequence is shown in SEQ ID NO.3. Introducing the dsRNA targeting LsBuEVE into the planthopper effectively inhibits LsBuEVE expression, significantly reduces the transcriptional level of the RSV nucleoprotein gene, protein accumulation, and the RSV acquisition rate in the planthopper, thereby effectively blocking RSV replication and transmission within the planthopper. This invention reveals for the first time the important role of the endogenous viral element LsBuEVE in the transmission of plant viruses by vector insects and provides a precise targeted control strategy based on RNA interference. Compared with traditional chemical pesticides, this technology has advantages such as high specificity, environmental friendliness, and low likelihood of developing resistance, and has broad application prospects and commercial value.

A method of preventing transmission of a virus from a mammalian subject. The method includes applying to a surface of the nasal cavity of the mammalian subject an aqueous composition. The aqueous composition includes a surfactant and a hydroxycarboxylic acid. The aqueous composition is at least substantially free of an antimicrobial agent. The aqueous composition has a viscosity of between 2,000 and 100,000 cps.

The invention provides a biological agent for inhibiting generation of a cell migration body, which comprises a Rac1 inhibitor NSC23766, and provides application of the biological agent in inhibition of virus transmission. Compared with the prior art, the invention has the following advantages: based on a newly discovered virus transmission mechanism, a biological preparation is developed, and a new target is provided for research in the antiviral field; the application of the small-molecule inhibitors NSC23766 and ISA-2011B is expanded, the small-molecule inhibitors NSC23766 and ISA-2011B are combined to regulate and control the generation of the migration body at different levels, the use concentration of the medicine can be remarkably reduced, and the important clinical application value is achieved.

This invention relates to a method for predicting the spread trend and range of Bluetooth viruses based on infection rate decay. The method first integrates multivariate data. Then, based on this data, the system is initialized to generate a road network, nodes, and their movement trajectories. Next, a model for predicting Bluetooth virus spread is constructed based on the initialized system and parameters. This model traverses nodes at discrete time points, acquiring the node's location and its neighbors within its signal radiation range, and calculating the node's current state. As nodes move and time progresses, the system repeats this process until the predicted end time is reached. Finally, based on the node's state at each discrete time point, the system outputs the changing patterns of the number of nodes in various states over time, thereby predicting the trend and range of Bluetooth virus spread, and presenting the results to the user in the form of a graph. This method can quickly understand the spread of viruses in a specific area, providing strong support for prevention and control decisions.

The application relates to the technical field of air conditioners, and provides a control method of an elevator air conditioner and the elevator air conditioner. The control method of the elevator air conditioner comprises the following steps: in response to an elevator door opening signal, the body temperature of a person entering the elevator is acquired; if the body temperature of the person is greater than or equal to a preset temperature, the fan of the elevator air conditioner is controlled to stop running, and a disinfectant water spraying device is controlled to disinfect the air in the elevator for a first preset time length after all the persons in the elevator leave the elevator. When the person enters the elevator, the temperature detection device acquires the body temperature of the person in time, and if the body temperature of the person exceeds the preset temperature, the fan of the elevator air conditioner is controlled to be closed in time, so that the speed of air flow in the elevator is slowed down. Secondly, after all the persons in the elevator leave the elevator, the air in the elevator is disinfected in time through the disinfectant water spraying device, and the duration is the first preset time length, so that the subsequent passengers can avoid contacting the air that may carry the influenza virus, and the risk of influenza virus transmission is reduced.

The invention provides a mask for preventing virus transmission, and relates to the field of health protection. A mask for preventing virus transmission is characterized by comprising a cylindrical mask body, a tightening mechanism connected to the bottom of the mask body, a disinfection air inlet and exhaust mechanism, a liquid dropping disinfection mechanism and a feeding mechanism, the disinfection air inlet and exhaust mechanism, the liquid dropping disinfection mechanism and the feeding mechanism are installed on the mask body, and the liquid dropping disinfection mechanism is located at the top of the mask body. When the anti-virus mask is used, only the mask body needs to be worn on the head, then the tightening mechanism is tightened, disinfection and ventilation can be conducted through the disinfection air inlet and outlet mechanism, the anti-virus mask can be suitable for being used for a long time, a comfortable environment and a high-fidelity music background can be provided, and the anti-virus mask is simple in structure and convenient to use.

The disclosure provides a Japanese encephalitis virus transmission risk estimation method and device and electronic equipment, relating to the technical field of disease transmission, the method comprises the steps of: determining a first infection force model, a second infection force model, a first incidence overflow rate model and a second incidence overflow rate model based on mosquito vector data, host infection kinetics data and host data corresponding to a first time interval; estimating the contribution coefficient of vertical transmission basic infection force and mosquito ovitraps index to the infection force of mosquito vector transmission to the host based on the first infection force model and the second infection force model; estimating the intensity coefficient based on the first incidence overflow rate model and the second incidence overflow rate model; estimating the host data of the second time interval based on the vertical transmission basic infection force, the contribution coefficient of the mosquito ovitraps index to the infection force and the intensity coefficient; in this way, the whole chain quantitative evaluation from mosquito vector to host and from host to host can be realized, and the risk evaluation accuracy of host infection virus in a real scene is improved.

The invention relates to the technical field of virus propagation path analysis, and discloses a virus propagation path analysis system and method based on big data, and the system comprises a propagation collection module and an intelligent analysis module. According to the system, management data of all municipal areas, management data of virus infected patients and all environmental factors affecting virus propagation are acquired through a propagation acquisition module and classified to form a data set, an intelligent analysis module sets a monitoring period, prevalence indexes are generated for the municipal areas where zero patients appear, and the prevalence indexes are analyzed. According to the method, the transmission range, the harm degree and the comprehensive condition of environment influence of viruses in jurisdictions are visually reflected, the multi-dimensional assessment precision is high, an intelligent analysis module focuses on transmission paths of three dimensions of population flow, material circulation and medical resources, the virus transmission risk degree between adjacent jurisdictions is assessed, risk indexes are generated, and the risk indexes are analyzed. Corresponding virus propagation prevention and control suggestions are output according to different virus types, a scientific prevention and control strategy which is graded according to popularity and applied according to propagation risks is established, and the intelligent prevention and control effect is good.

The invention belongs to the technical field of electric data processing, and particularly relates to a method for protecting secure transmission of remote contract data, in particular to an intelligent file security management method and device and a computer readable storage medium. In the remote contract file synchronization scene, an enterprise generally adopts the following processes: checking a signed contract, sending the contract to a server for transfer, receiving contract data sent by the server by a factory, and completing remote contract file synchronization, and the remote contract file synchronization adopts an intelligent file security management method for transmission. Only a binary data packet for changing image data is transmitted, a virus attachment carrier is cut off from the source, a downstream terminal reconstructs a contract based on a clean auxiliary contract database, direct execution of external files is avoided, the virus propagation risk is reduced, dependence on a feature library of a traditional antivirus program is not needed, meanwhile, the data transmission amount is reduced, and the efficiency is improved. And whether virus attachment exists can be judged according to the size of the data packet.

The application discloses an end-to-network cooperative measurement method and device for advanced persistent threats, and the method comprises the following steps: creating a virtual network and a plurality of virtual machines through a virtual machine manager; simulating an external Internet actual environment through a network simulation virtual machine; running a target advanced persistent threat virus sample through a virus execution virtual machine; collecting end-side system call behavior data through the virus execution virtual machine, and collecting network-side communication behavior data through the network simulation virtual machine; and transmitting the end-side system call behavior data and the network-side communication behavior data to a physical machine through a controller. The application can provide a controlled virtual environment for analyzing virus behavior, so that the virus sample is only executed in the virus execution virtual machine, the risk of virus spreading and infecting other systems is reduced, the collected end-to-network two-side data provides comprehensive information for analyzing the behavior characteristics of the virus, the efficiency and accuracy of virus sample analysis can be improved, and the application can be widely applied to the field of information security technology.