98 results about "Virus transmission" patented technology

The invention provides a virus propagation dynamic prediction method based on a multi-strain multi-region population model and related equipment. The method comprises the following steps: acquiring historical epidemic situation related data of a target area, wherein the historical epidemic situation related data comprises epidemic situation data, virus gene sequence data, population flow data and epidemic situation management policy data related to a target virus in a past time period of each area; arranging the population flow data into an asymmetric population flow matrix between different regions every day; sorting epidemic prevention grades corresponding to different epidemic situation management policies according to the epidemic situation management policy data; and constructing a multi-strain and multi-region population model based on epidemic situation data, virus gene sequence data, a population flow matrix and epidemic prevention grades corresponding to different epidemic situation management policies by taking StatPOMP as a model construction framework, and generating virus propagation dynamic prediction information based on the model. The prediction accuracy of the virus propagation trend can be improved.

The invention provides a network virus propagation prediction method based on a space-time diagram attention model, and mainly solves the problems of strong dependence on propagation parameters and low prediction precision in the prior art. The scheme comprises the following steps: 1) constructing a space-time infection state diagram based on a network topology structure and virus historical transmission data; 2) processing the historical virus transmission data by using a sliding window mechanism, and constructing a data set; 3) constructing a prediction model based on the space-time diagram attention network in combination with the diagram attention network and the long-short-term memory network; 4) training the prediction model by using the constructed data set, and evaluating the prediction performance of the model; and 5) predicting the propagation trend of the future network virus by adopting the trained model. According to the method, the spatial topological characteristics and the time evolution law of virus propagation are effectively combined, and meanwhile, a graph attention mechanism is introduced, so that the prediction accuracy and the calculation speed of virus propagation in a large-scale network environment can be remarkably improved.

The invention discloses a live pig epidemic prevention and control flow regulation system and method based on big data, and relates to the technical field of animal health information, and the method comprises the steps: recognizing abnormal live pig signals and track intersection features of structured epidemic prevention feature data through an intelligent algorithm, comparing the virus gene difference degree, constructing a virus propagation network diagram, and carrying out the analysis of the virus propagation network diagram; outputting a high-risk propagation node map; constructing an aerosol dynamics three-dimensional space model by taking a super propagation hub node of the high-risk propagation node map as an original point and combining culture environment parameters, simulating a virus air diffusion path, and generating an environment propagation thermal distribution map; fusing the high-risk propagation node map and the environment propagation thermal distribution map, identifying a cross infection area through a multi-dimensional risk superposition model to perform risk dynamic grading, and outputting a grading early warning report; according to the invention, breakthrough improvement of the live pig epidemic prevention and control capability is realized, key nodes and potential risk areas of epidemic propagation can be accurately identified, and the pertinence of prevention and control measures is improved.

The invention is applicable to the technical field of virus detection, and provides a norovirus detection kit based on a photo-thermal isothermal amplification technology and a detection method, the norovirus detection kit comprises a nucleic acid amplification chamber, the nucleic acid amplification chamber is provided with reaction micropores for nucleic acid amplification; an RT-PRA system, a CRISPR-cas12a system, a blank control and a positive control are placed in the reaction micropore, the RT-PRA system comprises RT-PRA solutions R1-R5, and the CRISPR-cas12a system comprises CRISPR-Cas12a solutions C1-C3; and the photo-thermal film covers the nucleic acid amplification chamber and is used for converting sunlight into heat energy and radiating the heat energy to liquid in the reaction micropores so as to provide reaction temperature for nucleic acid amplification. According to the invention, the portable, rapid and accurate detection of norovirus infection can be realized, the detection cost can be effectively reduced, the application scene is wide, workers can be helped to deduce the virus transmission path, and key support is provided for investigation and analysis of norovirus epidemic situations.

The application discloses a disease transmission link prediction method and system based on a dynamic hypergraph neural network, aiming to comprehensively depict virus transmission paths and risk levels from multiple dimensions. First, data is collected from a gene database, mobile device logs and clinical texts, virus variation characteristics, population contact relationships and symptom semantic information are extracted respectively, and a dynamic hypergraph that integrates virus strain nodes, individual nodes and regional nodes is constructed. The hyperedge is defined according to molecular similarity, space-time contact and semantic overlap, and the weight is dynamically adjusted according to the transmission intensity of the infectious disease. A multi-modal hypergraph neural network with variation perception is introduced to jointly model and adaptively fuse multiple types of hyperedges and multi-scale features, output node propagation embedding vectors and predict potential transmission chains, perform prevention and control responses, and realize real-time deployment and feedback loop in an edge-cloud collaborative manner, ensuring efficient and accurate infectious disease transmission modeling and intervention control while ensuring data privacy.

The invention discloses a disease transmission link prediction method and system based on a dynamic hypergraph neural network, and aims to comprehensively describe a virus transmission path and a risk level from multiple dimensions. The method comprises the following steps: firstly, collecting data from a gene database, a mobile equipment log and a clinical text, respectively extracting virus variation characteristics, a crowd contact relationship and symptom semantic information, and constructing a dynamic hypergraph fusing virus strain nodes, individual nodes and region nodes; the hyperedge is defined according to molecular similarity, space-time contact and semantic overlap, and the weight is dynamically adjusted along with the infectious disease transmission intensity. A multi-modal hypergraph neural network of variation perception is introduced, joint modeling and adaptive fusion are performed on multi-type hyperedge and multi-scale features, a node propagation embedded vector is output, a potential propagation chain is predicted, prevention and control response is executed, and real-time deployment and feedback closed loop are realized in an edge-cloud cooperation mode. And efficient and accurate infectious disease transmission modeling and intervention control are completed on the premise of ensuring data privacy.

The invention discloses a biological data anomaly detection method based on semantic information fusion, and relates to the technical field of computer processing, and the method comprises the following steps: S01, constructing biological entity nodes and relation edges through a depth map neural network, generating an adjacency matrix and a node attribute matrix, aggregating node neighbor information by using a message passing mechanism, and generating a node attribute matrix; a biological network architecture model is obtained; s02, constructing a semantic fusion space based on a large model, analyzing deep semantic information and node association information of nodes, and synthesizing a few abnormal node candidate sets; and S03, adding the composite node candidate sets into the original data set one by one through an edge generator, and inputting the composite node candidate sets into a reinforcement learning module for screening. According to the method, classification and risk assessment of biological data are optimized by utilizing large-model semantic analysis and biological network construction, so that abnormal biological data can be quickly identified through multi-source data fusion and deep learning analysis in the early stage of virus transmission, and accurate detection and intelligent early warning are realized.

The invention provides an isolation device, and relates to the technical field of infectious disease prevention and control isolation, the isolation device comprises an isolation monitoring base, the top end surface of the isolation monitoring base is provided with a treading groove, and the center of the bottom surface of the inner end of the treading groove is fixedly provided with a proximity sensing assembly; through fixed installation of a matching strip block and a door plate of a room door, when an isolated person opens the room door of the room for prevention and control isolation of infectious diseases, first, information is wirelessly transmitted to a monitoring center, and second, information is transmitted to the monitoring center; therefore, an isolation prevention and control worker in the monitoring center can know the current behavior of opening the door of the isolated person at the first time, and the problem that key behaviors such as approaching or opening the door cannot be found and processed in time due to the lack of behavior supervision on the isolated person when the person is isolated in a single room is solved. And the hidden danger of virus transmission caused by isolation failure exists.

The present invention is a two-state feedback controller that takes into account the influence of spatio-temporal diffusion and individual contact heterogeneity. The controller design method includes: Step 1: Establish an SIR epidemic model; Step 2: Apply a two-state feedback controller to the SIR epidemic model; Step 3: Linearize the SIR epidemic model under the action of the two-state feedback controller at the equilibrium point to obtain the characteristic equation of the linearized controlled SIR epidemic model; Step 4: Select the time delay as the bifurcation parameter, and through stability analysis and bifurcation analysis of the characteristic equation of the linearized controlled SIR epidemic model, select appropriate state feedback parameters to make the model locally asymptotically stable near the equilibrium point. The two-state feedback controller of the present invention can perform feedback regulation control according to the state variables of susceptible individuals and infected individuals at the same time, and does not affect the characteristics of the original system, so as to efficiently and safely regulate the virus transmission process.

This invention discloses a purifying fan, comprising a base, a fan housing, an impeller, a motor, and a purification component. The fan housing has an air chamber and is equipped with an air inlet and an air outlet, both communicating with the air chamber. The base is connected to the fan housing by a fixing member. The motor is mounted on the base, and the impeller is placed in the air chamber. The motor is connected to the impeller via a rotating shaft to drive the impeller to rotate. The purification component includes a purification shell, an ion generator, and an ion purification element. The purification shell is located on the side near the air inlet and has a purification chamber. The ion purification element is located in the purification chamber, and the ion generator is electrically connected to the ion purification element. The purification shell is equipped with an air collection port and an air guide port communicating with the purification chamber, and the air guide port is connected to the air inlet. This device not only functions as a fan but also purifies indoor air, reducing dust and microorganisms in the air and lowering the risk of virus transmission.

The application provides a dengue virus protection and mosquito vector control antigen composition and application thereof. The antigen composition comprises a combination of dengue virus type 1-4 envelope protein domain III polypeptide and Aedes aegypti midgut mucin AaMuc1 antigen polypeptide; the amino acid sequences of the dengue virus type 1-4 envelope protein domain III polypeptide are respectively shown as SEQ ID NO. 1, SEQ ID NO. 2, SEQ ID NO. 3 and SEQ ID NO. 4; and the amino acid sequence of the Aedes aegypti midgut mucin AaMuc1 antigen polypeptide is shown as SEQ ID NO. 5. The prepared vaccine can induce the body to produce neutralizing antibodies against dengue virus type 1-4, achieve the protection of human body from dengue virus infection, induce the production of active antibodies targeting Aedes aegypti midgut mucin 1, inhibit and kill the dengue virus transmission vector Aedes aegypti, and achieve the dual prevention and control of dengue fever from two dimensions of infection prevention and transmission interruption.

The utility model relates to an endoscope pipeline brush which comprises a shell, a rotating shaft and a pliers pipeline brush. A cavity is formed in the shell, an extending hole is formed in one side of the shell, the rotating shaft is arranged in the cavity and rotationally connected between the two inner side walls of the shell, one end of a brush rod of the pliers pipeline brush is fixedly connected with the rotating shaft, and the other end of the brush rod is wound by the rotating shaft, extends out of the extending hole and is connected with a brush head of the pliers pipeline brush. According to the technical scheme, the brush rod of the plier pipeline brush can be wound around the rotating shaft in the shell, occupied storage space is reduced, the plier pipeline brush can be pulled out by a specified length to be used according to use requirements, operation flexibility is improved, and the situation that a traditional plier pipeline brush is too long and not easy to operate is avoided; the brush rod part which does not extend out can be kept clean, virus transmission is reduced, and the cross infection risk is reduced.

This utility model discloses a positive and negative pressure switching fresh air system, comprising: an intake fan connected to an air distribution box via pipes, the air distribution box connected to the intake valves of each room via pipes and silencers; a return fan connected to a collection box via pipes, the collection box connected to the return air valves of each room via pipes; when the intake fan is turned on and all the intake and return air valves of all rooms are fully open, all rooms are in a positive pressure state; when the return fan is turned on and all the intake and return air valves of all rooms are fully open, the return air volume is greater than the intake air volume, and all rooms are in a negative pressure state; when both the intake and return air fans are fully open, if room 1 opens its intake valve and closes its return air valve, room 1 is in a positive pressure state; if room 2 opens its return air valve and closes its intake valve, room 2 is in a negative pressure state; positive pressure rooms prevent virus intrusion, and negative pressure rooms prevent virus spillover; infected individuals live in negative pressure rooms, and uninfected individuals live in positive pressure rooms, which can prevent cross-infection among family members and is very suitable for the current virus transmission situation.

A viral transmission barrier suitable for group settings encountered in places such as school or workplace cafeterias. The article aspect is a viral transmission barrier for tables with a height and a top surface with a length, a width, and a perimeter configured to accommodate a group of at least two people that may be strangers sitting in chairs at the perimeter and each having a section of table perimeter before them. Specifically, the article aspect comprises four elements, a multitude of vertical side panels, at least one neighboring vertical panel, a releasably attaching element, and a horizontal ceiling panel. The method aspect is aa method of using a viral transmission barrier to prevent the transmission of airborne viral particles from an infected person to others of a group of at least two people that may include strangers and are sitting in chairs at a table with a perimeter and each having at least 24 in, (61 cm) of perimeter before them at a function where masks are not worn. Specifically, the method comprises five steps.

The invention provides a fluorescent quantitative PCR (polymerase chain reaction) detection primer, a kit and a method for a novel variable chalmavirus VP gene, and belongs to the technical field of virus detection. A specific primer is designed and synthesized according to a conserved sequence of a VP gene of the novel variant chalmavirus, a recombinant plasmid is constructed, then the recombinant plasmid is used as a standard substance to establish a standard curve, a real-time fluorescent quantitative PCR detection system aiming at the novel variant chalmavirus is constructed, and specific detection of the novel variant chalmavirus is realized. The detection method can be used for quantitatively detecting the novel variant chalmavirus in the to-be-detected sample, and has the characteristics of high speed, high sensitivity, strong specificity and the like; the method provides a key technical support for molecular epidemiological investigation of the Sepamavirus in animal populations, is helpful for realizing early screening of infected individuals and timely blocking of virus transmission, and has important practical significance for guaranteeing population health and maintaining high mountain ecosystem stability.

The present application provides an asynchronous multi-threaded self-service sampling method, server-side equipment, system and electronic terminal, including: obtaining the identity identification information of the person to be tested, thereby obtaining the detection task corresponding to the person to be tested; classifying the detection tasks of the same type into the same detection task queue, and queuing and managing different detection task queues and their corresponding detection tasks through multi-threading; responding to the asynchronous online self-service sampling request information of the person to be tested, supervising and guiding the online self-service sampling process of the person to be tested by conducting online video in the corresponding thread to obtain qualified self-service sampling samples; thereby realizing safe and efficient self-service sampling of asynchronous multi-threading. The present application can realize self-service, parallel multi-person, continuous multi-frequency sampling through asynchronous multi-threading, and the person to be tested can complete the sampling work at home by themselves, thereby reducing the risk of virus transmission.

The utility model discloses an automatic cleaning laying hen breeding cage, including hencoop, excrement cleaning mechanism, crib cleaning mechanism and control panel, control panel is installed on one side of hencoop, the hencoop is formed by connecting cage body and frame, excrement cleaning mechanism includes collecting tank, screw transmission group, support seat, cleaning box and cleaning roller, and the cleaning roller is connected with the collecting tank. The feeding trough cleaning mechanism comprises a flow guide pipe and a scraping plate. The chicken coop is provided with the excrement cleaning mechanism, the feeding trough cleaning mechanism and the control panel, excrement generated by laying hen breeding can be automatically collected, excrement adhering to the bottom face of the chicken coop can be cleaned, peculiar smells and virus spreading in a breeding house are reduced, meanwhile, residual feed in the feeding trough is cleaned, and the breeding efficiency is improved. Bacteria breeding in the feeding trough is avoided, a good feeding environment is provided for laying hens, and the egg laying yield is increased.

The application discloses a tomato Soly04g076730 Gene or its encoded protein is applied to resisting plant geminivirus. Soly04g076730 The gene is transiently expressed or stably genetically transformed in a plant leaf. When a virus invades the plant, the plant immune response is rapidly induced, and the disease resistance of the plant is improved. The Soly04g076730 protein is a secretory protein. The plant immune ability can be improved by expressing or externally applying the protein in the plant, and the virus transmission and replication can be effectively inhibited.

This utility model discloses an elevator call device based on Time-of-Flight (ToF) technology, belonging to the field of elevator control equipment technology. It includes a housing with a sensor window extending through its front end and a projection window extending through its front end near the upper edge. This utility model, through the cooperation of a projection display module and a ToF sensor module, fundamentally eliminates direct contact between the user and the device surface using non-contact ToF technology. Compared to traditional contact-based elevator call devices, it effectively reduces the transmission routes of bacteria and viruses, significantly lowering the risk of cross-infection between patients. In places with high population mobility, it provides users with a safer and healthier elevator environment, meeting the growing demand for public health and safety.

The invention provides a closed three-classification four-chamber integrated garbage can, relates to the technical field of garbage collection devices, and has the characteristics of fire prevention, water prevention, virus transmission prevention, easiness in waste battery recovery and the like which are not possessed by existing equipment. The mobile integrated garbage storage vehicle comprises a shell, a mobile integrated garbage storage vehicle is placed in the shell, two sides in the vehicle are respectively provided with a large bin, the top of each large bin is a garbage bin inlet, a folding baffle is arranged for sealing, the middle of each large bin is a battery bin, the top of each battery bin is a cigarette end bin, and an upper hole and a lower hole in the middle of the shell are respectively a battery bin inlet and a cigarette end bin inlet. Pull rod power-assisted clamps with bearings are arranged at the two ends of the folding baffle and connected with pull rods, the other ends of the pull rods are connected with pedals with buffer springs, the folding baffle is pulled open in a linkage mode by stepping on the pedals, and the folding baffle is automatically closed after leaving the pedals and returning to the center. The environmental pollution is effectively reduced.

The utility model provides an epidemic disease prevention and control device, which relates to the technical field of epidemic disease prevention and control and comprises a support structure, the support structure is composed of a stabilizing plate and a stabilizing frame, a rotating shaft is mounted at the bottom of the stabilizing plate, two rollers are mounted on two sides of the rotating shaft respectively, and a storage is mounted between the stabilizing plate and the stabilizing frame. Through the unique mechanical structure design, automatic liquid spraying operation is achieved, when the pushing device enables the idler wheel to drive the rotating shaft to rotate, through a series of transmission cooperation such as bevel gear transmission, a cam mechanism and gear meshing, the spraying head can be automatically driven to swing in a reciprocating mode and spray prevention and control liquid, and the spraying efficiency is improved. Compared with traditional manually-operated spraying equipment, the spraying efficiency is greatly improved, the human input is reduced, comprehensive spraying can be completed in a shorter time, the efficiency of epidemic disease prevention and control work is effectively improved, and the virus spreading risk is reduced in time.

The invention relates to the technical field of infectious disease prediction, in particular to an infectious disease transmission risk prediction method and system based on big data analysis, and the method comprises the steps: firstly collecting multi-source heterogeneous data of population flow, environmental meteorology, historical epidemic situation, social media and public health resources, and then carrying out the cleaning, fusion and space-time alignment of the data, constructing a standardized database, training a dynamic propagation model based on machine learning, iteratively optimizing parameters by combining an SEIR improved model and real-time data, and finally outputting a regional risk level prediction result and a visual early warning map; according to the method, the multi-source heterogeneous data are fused, and the dynamic machine learning model is used for real-time analysis, so that complex influence factors of virus transmission can be more comprehensively captured, prediction deviation caused by single data or update delay in a traditional method is remarkably reduced, the risk early warning precision is improved, and the risk early warning efficiency is improved. And minute-level data processing and risk level updating are realized.

The invention relates to an air purifier control method and device, an air purifier, a computer readable storage medium and a computer program product. Early warning information and air quality information of the environment where the air purifier is located are obtained firstly. And under the condition that the early warning information is obtained, the air purifier is controlled to enter the first operation mode, all the purification units in the air purifier are triggered to operate, so that the air purification and disinfection effects are achieved to the maximum extent, emergency events can be quickly responded, the concentration of pathogens in air is reduced, the virus spreading risk is reduced, and the safety of the indoor environment is improved. And under the condition that the early warning information is not obtained, the target operation mode of the air purifier is determined according to the air quality information, the purification unit corresponding to the target operation mode is started to operate, that is, the corresponding purification unit is operated according to the actual indoor air quality requirement, the purification efficiency is optimized, energy consumption and equipment abrasion are reduced, and the service life of the air purifier is prolonged. And the service life of the air purifier is prolonged.

The utility model discloses an excrement and trough cleaning and disinfecting device for a laying hen farm, which comprises an excrement cleaning and disinfecting unit, a trough cleaning and disinfecting unit and a control panel, and the excrement cleaning and disinfecting unit comprises a support frame, a conveying belt, a cleaning box, a cleaning box, a disinfecting box and a drying box, the feeding trough cleaning and disinfecting unit comprises an electric sliding rail, a feeding trough scraping plate, a flushing and disinfecting pipe and a residue discharging pipe, and all electric control components in the excrement cleaning and disinfecting unit and the feeding trough cleaning and disinfecting unit are connected and controlled through wires and a control panel; according to the utility model, the manure cleaning and disinfecting unit, the trough cleaning and disinfecting unit and the control panel are arranged on the coop for combined use, so that manure generated by laying hen breeding can be collected and treated, and then the conveying belt for conveying the manure is disinfected to reduce peculiar smell and virus transmission in a breeding house; in addition, the feeding trough of the coop can be cleaned and disinfected, bacteria breeding in the feeding trough is avoided, a good feeding environment is provided for laying hens, and the egg laying yield is increased.

This application relates to a dining device for patients in makeshift hospitals, belonging to the technical field of dining equipment. The dining device includes a dining cart and an isolation component. The isolation component and the dining cart work together to form a dining space. The isolation component includes an isolation cover mounted on the dining cart, with a dining entrance on the cover and a closing device on the cover for adjusting the size of the dining entrance. Because of the isolation component, the dining space is isolated from the outside environment during meals. The isolation component includes an isolation cover and a closing device on the cover for adjusting the size of the dining entrance. Patients can enter the dining space through the closing device, which fits snugly against the patient's body surface. Therefore, the patient's dining space is isolated from the outside environment, and air is confined within a certain range to prevent the circulation of virus-laden air with the outside air, reducing the risk of virus transmission.

Device for the preventive blocking of neurotropic viruses in the peripheral nervous system, comprising a biochemical injection system for the localized release of a neurospecific binding molecule, a detection unit for the identification of viral particles in neuromuscular tissue, and a receptor bait structure for binding viral glycoproteins with affinity for neuronal receptors, characterized in that the device prevents retrograde axonal viral transmission without permanently impairing the conductivity of the nerve tissue.

The invention belongs to the technical field of biology, and particularly relates to a screening method of a small molecule compound for inhibiting insect-borne diseases and related application. In order to solve the problem that crop production is seriously harmed due to efficient aphid virus transmission, starting from the aphid feeding and virus obtaining process, a virtual screening-molecular docking method is adopted, Chinese gall bodies interacting with aphid colloidal salivary protein sheath protein are screened out for tanning, the Chinese gall bodies are used for tanning, viruses attached to the tip of an aphid mouth needle are reduced, and the aphid yield is improved. And the transmission efficiency of the virus is reduced.

The invention relates to the field of bioengineering, in particular to a recombinant collagen which is characterized by comprising one or more of the following characteristics: a, an amino acid sequence of the collagen is shown as any one of SEQ ID NO.1-4; and b. A, the collagen is added, substituted or deleted with one or more amino acids, and the protein has collagen activity. The recombinant collagen prepared by utilizing a genetic engineering technology has the remarkable advantages of stable quality, no virus transmission risk and the like, and has a good application prospect in the field of medical materials.

The application discloses a network virus propagation prediction and defense method and system, and belongs to the technical field of network security. The method constructs a dynamic infection state graph dataset indexed by time, each time step containing a node security attribute feature matrix and an infection state sequence; a spatial feature matrix is extracted through a graph attention network, and a global time feature matrix is extracted through a Transformer encoder; the global time feature is used as a query vector, and the spatial feature is used as a key-value pair, which are weighted and aggregated through a cross-attention mechanism to obtain a fusion feature matrix, and an infection state prediction result is mapped and output; the security attributes and topological context features of high-risk nodes in the prediction result are extracted and mapped into query vectors, enhanced knowledge is retrieved from an external knowledge base based on the query vectors, prediction information, security attributes, topological contexts and enhanced knowledge are input into a large language model to generate an active defense strategy, and an automatic closed loop from virus propagation prediction to active defense is realized.

The application provides a full-automatic medical garbage can and relates to the field of medical equipment.The full-automatic medical garbage can comprises a garbage can body and a lower cover, the garbage can body and the lower cover are connected through bolts, the top end rear of the garbage can body is rotationally connected with an upper cover, the bottom end left side of the upper cover is fixedly connected with a first silica gel strip, the bottom end middle part of the upper cover is fixedly connected with a linear motor, and the driving end of the linear motor is fixedly connected with a second silica gel strip.The bottom of the garbage bag is pulled to the bottom of the garbage can through the viscous tube, then the second silica gel strip is separated from the first silica gel strip to tear the bag opening by the linear motor, and finally the garbage bag is blown open by the air blower, so that the full-automatic and non-contact installation of the garbage bag is realized, the risk of virus transmission is reduced, the garbage bag is labeled by the labeling machine to facilitate the traceability of the garbage bag, problems can be treated in time, and the safety guarantee is further improved.