53results about How to "Avoid nerve damage" patented technology

The subject invention provides R(+)-N-propargyl-1-aminoindan and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions containing same. The subject invention also provides methods of treating a subject afflicted with Parkinson's disease, a memory disorder, dementia, depression, hyperactive syndrome, an effective illness, a neurodegenerative disease, a neurotoxic injury, stroke, brain ischemia, a head trauma injury, a spinal trauma injury, neurotrauma, schizophrenia, an attention deficit disorder, multiple sclerosis, or withdrawal symptoms, using R(+)-N-propargyl-1-aminoindan or the pharmaceutically acceptable salt of the subject invention. The subject invention further provides a method of preventing nerve damage in a subject. Finally, the subject invention provides methods of preparing R(+)-N-propargyl-1-aminoindan, a salt thereof, and racemic N-propargyl-1-aminoindan.

The invention provides a preparation method of an oxidized regenerated cellulose hemostatic material with a micro-nano composite structure and relates to a preparation method of an oxidized regenerated cellulose hemostatic material. The invention aims to solve the problems of low hemostatic speed, great effect on environment and uneasiness in decomposition of the existing hemostatic material. The preparation method comprises the following steps: firstly, preparing cellulose solution; secondly, netting fibers in a wet state and reinforcing into a nano layer cellulose non-woven fabric; thirdly, preparing an oxidized nano cellulose non-woven fabric and oxidized viscose staple fibers; and fourthly, cotton-slitting and cotton-carding the oxidized viscose staple fibers prepared in the step 3 and compounding to obtain the oxidized regenerated cellulose hemostatic material with the micro-nano composite structure. The preparation method is applied to the preparation field of the oxidized regenerated cellulose hemostatic material.

The invention relates to the field of medical instruments, in particular to a sacroiliac joint through-screw positioning coaxial guide and an assembly thereof. The sacroiliac joint through-screw positioning coaxial guide comprises a first positioning rod for fixing a first puncture sleeve, a second positioning rod for fixing a second puncture sleeve, an adjusting device for adjusting a relative distance between the first positioning rod and the second positioning rod, and a fixing device for fixing the positions of the first positioning rod and the second positioning rod. The first positioningrod and the second positioning rod are respectively connected with the adjusting device, and the first positioning rod and the second positioning rod are axially symmetric by taking a vertical centerline of the adjusting device as an axis of symmetry, such that a horizontal centerline of the first puncture sleeve and a horizontal centerline of the second puncture sleeve are in the same line. Thefixing device is connected with the adjusting device. A sacroiliac joint screw can penetrate through a sacroiliac joint and can be accurately placed into the patient body, so that the surgical positioning is accurate, the stability is high, the safety is high, and complications such as vascular nerve injury are avoided.

Provided are a medical insertion apparatus includes a screw body to be inserted into a body, and an electrode provided in the screw body and including an externally exposed portion, wherein a through-hole may be provided in the screw body or the electrode, and a medical insertion apparatus includes a screw body to be inserted into a body, and an electrode provided in the screw body and exposed to an outside of the screw body, wherein the screw body and the electrode may be provided in a connectable or separable structure.

The invention provides new methods for treating certain disorders resulting from neurodegeneration and for treating depression which comprise administration of NR2B subunit selective NMDA antagonists. The disorders that can be treating by the invention include hearing loss, vision loss, neurodegeneration caused by epileptic seizures, neurotoxin poisoning, Restless Leg Syndrome, multi-system atrophy, non-vascular headache, and depression.

According to one embodiment, a medical insertion apparatus includes a screw nail body inserted into a human body and an electrode which is provided in the screw nail body and includes an externally exposed portion. Here, a through hole may be formed in the screw nail body or the electrode. According to one embodiment, a medical insertion apparatus includes a screw nail body inserted into a human body and an electrode which is provided in the screw nail body and exposed outside the screw nail body. Here, the screw nail body and the electrode may be provided as a combinable or separable structure. According to one embodiment, a medical insertion apparatus includes a screw nail body inserted into a human body, a driver engaged with the screw nail body to tighten or loosen the screw nail body, and a conductor portion which may be provided in the screw nail body or the driver and may include an externally exposed portion.

The invention discloses a leg fixator with an adjusting function for orthopedic patients, comprising a base, a thigh fixture and a shank fixture. One end of the base is rotationally connected with oneend of a thigh fixing plate, and the other end of the thigh fixing plate is rotationally connected with the shank fixture; the end of the shank fixture far away from the thigh fixture is symmetrically provided with two foot positioning devices; each foot positioning device includes a support rod vertically arranged, a first threaded rod is horizontally arranged at the upper end of the support rod, one end of the first threaded rod is provided with a first retaining plate that limits the two sides of the foot, the other end of the first threaded rod sleeves the support rod, the threaded rod isprovided with an extension terrace that is horizontally sleeved with a second threaded rod, and one end of the second threaded rod is provided with a second retaining plate that limits the sole. Theleg fixator is simple in structure and low in cost, allows a patient's legs to be quickly and accurately fixed to avoid side-to-side shaking of the legs, and is convenient to operate so that workloadis greatly reduced for medical staff and working efficiency is improved.

The invention discloses a needle knife. The needle knife comprises a needle handle and a first needle body. The needle handle is provided with a movable device; one end of the first needle body is fixed to the movable device, and the other end of the first needle body is provided with a needle edge or a dull edge; a second needle and the first needle are arrange side by side in the length direction; the second needle body is fixed to the movable device, and the other end of the second needle body is provided with a cutting sharp edge; the second needle body or the first needle body is driven by the movable device so that the second needle body and the first needle body can move relative to each other, and a first work station and a second work station are formed respectively; when the needle knife is located on the first work station, the needle edge or the dull edge goes beyond the cutting sharp edge so that the needle edge or the dull edge can work and the cutting sharp edge cannot work; when the needle knife is located on the second work station, the cutting sharp edge goes beyond the needle edge or the dull edge so that the cutting sharp edge can work and the needle edge or the dull edge cannot work. The combined needle knife can provide the function of free switching between the dull edge and the cutting sharp edge, and all parts of the needle knife are allowed to move in a retractable mode so as to provide quick selective operation of sharp, dull and special functions of the needle knife for a doctor.

The invention relates to an instant adhesive tissue patch and a preparation method thereof, and belongs to the technical field of medical materials. The instant adhesive tissue patch comprises a meshsubstrate, the mesh substrate is coated with a fibrinogen complex layer and a prothrombin layer, and the fibrinogen complex layer and the prothrombin layer are frozen at an ultralow temperature. The instant adhesive tissue patch can be rapidly attached to tissue without suture lines or drawing pins, so that nerve injury caused by fixation can be avoided and operation time is greatly saved; the patch is directly placed at an operation defect part in use, and thrombin and fibrinogen are crosslinked in a body fluid wet environment to quickly form fibrin glue for fixing the patch to the tissue; and the effects of rapid hemostasis and wound healing can be achieved at the same time.

A new method employing a known compound, bupropion hydrochloride (.±.)-1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride, and its analogues, in a new use for the treatment of TNF-related disorders is described.

A three-dimensional fracture fixation device is provided for treating clavicle fracture with the intent to protect the supraclavicular nerve from later iatrogenic transsection injury that may occur when the fixation bone plate is removed. The essential components of the three-dimensional fracture fixation device include at least one fixation locking plate, a nerve protection scutum (shield), junctional hooks connecting the fixation locking plate and supporting the nerve protection scutum (shield), and bone screws, which are assembled to form a defined space to accommodate the supraclavicular nerve during open reduction and internal fixation.

Provided are a medical insertion apparatus including a screw body to be inserted into a body, and a conductive portion provided in the screw body and including an externally exposed portion, wherein the conductive portion may extend in a longitudinal direction of the screw body and form a single closed loop, and a medical insertion apparatus including a screw body to be inserted into a body, a driver to engage with the screw body to be used to fasten or loosen the screw body, and a conductive portion provided in the screw body and the driver and including an externally exposed portion on one side of the screw body, wherein a portion of the conductive portion disposed in the screw body and another portion of the conductive portion disposed in the driver may be electrically connected to each other.

The invention relates to the technical field of tissue engineering, in particular to a Schwarm progenitor cell derived from a marrow neural crest cell and application of the Schwarm progenitor cell to promotion of nerve regeneration. The rat marrow-derived neural crest cell N1, namely, BM-NCC clone N1, is provided, the preservation number is CCTCC NO:C201647, and the rat marrow-derived neural crest cell N1 has the performance of the Schwarm progenitor cell (SCP). The invention further provides a subculture method of the BM-NCC clone N1 and a method for induced directional differentiation to the Schwarm cell (SC). The BM-NCC clone N1 is expected to be applied to nerve regeneration promotion therapy based on cells.

This invention pertains to the discovery that agents which inhibit the binding of cortisol to its receptors can be used in methods for preventing neurological damage associated with glucocorticoid therapy in ventilator-dependent low birth weight preterm infants. Mifepristone, a potent glucocorticoid receptor antagonist, can be used in these methods.

The invention discloses a surgical lateral-position peripheral nerve and skin injury protection device, which comprises a bed body and a leg pneumatic cushion. A signal transceiving device is clampedat one end of the bed body. The device is reasonable in design and convenient to use; by arrangement of the leg pneumatic cushion and hand pneumatic cushions, a patient with hands on the hand pneumatic cushions and legs on the leg pneumatic cushion can conveniently lie on side after surgical completion; by pneumatic massage for simulating hand massage, workload of operating room nurses is reduced,and an optimal nerve injury prevention effect is achieved; by arrangement of the signal transceiving device, a control chip and a heater, remote control with mobile phone APP can be realized conveniently through the signal transceiving device, convenience and quickness in use are achieved, manual adjustment is avoided, the heater is capable of conveniently heating the leg pneumatic cushion and the hand pneumatic cushion, and convenience in constant-temperature massage is achieved. The surgical lateral-position peripheral nerve and skin injury protection device is simple, convenient and suitable for extensive popularization.

The invention provides a nerve block anesthesia medicine injection pressure measurement alarm device under ultrasound, and relates to the field of medical equipment. The nerve block anesthesia medicine injection pressure measurement alarm device under ultrasound comprises an injection device, a three-way pipe is arranged on the right side of the injection device, an ultrasonic device is arranged above the three-way pipe, an injection device is arranged on the right side of the three-way pipe, and a control device is arranged on the right side of the injection device. Through the arrangement ofa pressure sensor and an alarm lamp, during anesthesia medicine injection, the pressure of injection liquid can be monitored, high-pressure injection is avoided, and nerve injuries or neurological dysfunction are avoided. The anesthetic injection position is detected through ultrasound, precise anesthesia is achieved, extra pain caused by repeated blind detection to a patient is avoided, the anesthesia efficiency and safety are improved, and the medication cost is reduced. The injection speed is controlled through a motor, and low-pressure anesthetic injection can be conducted smoothly.

It is disclosed a needle (1) for a syringe, including a tip (2) at one end (3) of the needle, adapted to penetrate a body tissue during usage of the syringe, and a hub (4) at the other end (5) of the needle, to attach the needle to the syringe. A pressure sensor (6) is in the needle; means (7) are provided to transmit outside the needle a pressure value sensed by the pressure sensor (6) in the needle.

The invention relates to a variable-angle V-shaped double-channel working sheath for spine endoscopic surgery. The variable-angle V-shaped double-channel working sheath comprises a working sheath grab handle body, wherein a clamping ring is arranged on the working sheath grab handle body and used for being connected with a detachable connecting grab handle or a robot or a mechanical arm, and the working sheath grab handle body is provided with a working sheath channel I and a working sheath channel II which are independent of each other; and the bottoms of the working sheath channel I and the working sheath channel II are connected side by side through an elastic rotating shaft, the tops of the working sheath channel I and the working sheath channel II are jointly connected to an elastic opening structure, and an endoscope locking depth adjuster is further embedded in the upper end of the working sheath channel I. The angles of the two channels of the working sheath can be adjusted, the depth of the connected endoscope can be adjusted in real time, windows are formed in the tail ends of the instrument channels, the flexibility of instrument operation is improved, the endoscope is prevented from being damaged, the injury risk generated by surgical instruments is reduced, and the situation that the surgical instruments cannot be observed by the endoscope in the surgical process is avoided.