The invention relates to the field of orthopedic surgical instruments, and provides a guiding device for orthopedic surgery, the guiding device comprises a fixed base, a support shaft is arranged in the fixed base, a first rotating plate and a second rotating plate sleeve the support shaft, a rotating cavity is arranged in the first rotating plate, and a rotating outlet communicated with the rotating cavity is formed in one side of the first rotating plate; a connecting through hole penetrating through the rotating cavity and matched with the supporting shaft is formed in the top face of the first rotating plate, the second rotating plate comprises a rotating part located in the rotating cavity and arranged on the supporting shaft in a sleeving mode, and a connecting part penetrating through the rotating outlet extends from the side face of the rotating part; clamping connecting arms penetrating through the fixed base are arranged at the ends, away from the supporting shaft, of the connecting part and the first rotating plate correspondingly, and the two clamping connecting arms are arranged in a mirror image mode; a guide assembly is arranged at one end of each clamping connecting arm, a control assembly is arranged between the other ends of the two clamping connecting arms, and the control part of the control assembly is hinged to the clamping connecting arms; the problems that an existing drilling guide device is complex in structure, and the guide precision is reduced after long-time use are solved.