The present invention discloses a flow cell and a liquid chromatograph having the same. The flow cell comprises a housing, a cell core, a liquid core waveguide, an inlet connection module and an outlet connection module. The housing is configured to limit an installation cavity, and the cell core is arranged in the installation cavity and is internally provided with a liquid channel, a liquid inlet tank and a liquid outlet tank. The two ends of the liquid channel respectively communicate with the liquid inlet tank and the liquid outlet tank, the liquid inlet tank penetrates an inlet pressing block, the liquid inlet tank communicates with the liquid outlet tank, an incident light tube penetrates the inlet pressing block, the incident light tube communicates with the liquid inlet tank, and the outlet connection module is butted against one end, provide with the liquid outlet tank, of the cell core. The outlet connection module is provided with a light emitting hole directly facing the liquid outlet tank. According to the embodiment of the invention, the flow cell can reduce the possibility of energy loss and generation of stray light so as to improve the detection precision of the liquid concentration.