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48results about How to "Increase the amount of effective data" patented technology

Graded diagnosis and treatment evaluating method based on data mining

The invention discloses a graded diagnosis and treatment evaluating method based on data mining. The method comprises the steps: extracting essential information and diagnosis and treatment information on patients from medical records, associating the essential information and the diagnosis and treatment information with disease category information and medical institution information, and firstly, carrying out data cleaning and missing value filling so as to divide the patients into patients of different flow directions; then, calculating graded diagnosis and treatment monitoring indexes by using the data; portraying visiting behaviors and features of different patients by a GainRatioAttributeEva feature selection algorithm and a RIPPER sorting algorithm. According to the method, through evaluating graded diagnosis and treatment by qualitative indexes and quantified indexes, the defects in the current graded diagnosis and treatment evaluating methods that only the quantified indexes exist, the indexes are required to be reported layer upon layer, mis-reporting and confused reporting occur during reporting, and the tracking of reasons behind the indexes is absent are overcome; by using a data mining technology, graded diagnosis and treatment evaluation is more timely and accurate.
Owner:CHENGDU SHULIAN YIKANG TECH CO LTD

Plasma cfDNA (cell-free deoxyribonucleic acid) bi-molecular marker, method for marking and detecting plasma cfDNA and application of plasma cfDNA bi-molecular marker

The invention provides a plasma cfDNA (cell-free deoxyribonucleic acid) bi-molecular marker. The bi-molecular marker is oligonucleotide, the sequence is represented as follows: a) 5'P-GACGTC-GATCGGAAGAGCTCGTATGCCGTCTTCTGCTTG, b) 5' ACACTCTTTCCCTACACGACGCTCTTCCGATCT-NNNNNNNNNNNNNNNNNNNN-GACGTCT, the sequence of oligonucleotide is from the 5' terminal to the 3' terminal from left to right, N represents a random basic group, and P represents a phosphate group; the oligonucleotide sequence is synthesized artificially. The plasma cfDNA bi-molecular marker is used for distinguishing every plasma cfDNA molecule by adding a unique molecular marker to every plasma cfDNA molecule and can be applied to plasma cfDNA detection. The plasma cfDNA bi-molecular marker overcomes defects of cfDNA detection with a conventional NGS (next generation sequencing) technology, and specifically has following technical effects: 1), the cfDNA valid data volume in a database construction process is increased; 2), noise signals such as deviation and detection errors produced in intermediate steps of gene detection can be reduced; 3), target variation can be effectively detected, meanwhile, low false positive rate is realized, and accuracy and stability of gene detection are improved.
Owner:GUANGZHOU REFORGENE MEDICINE CO LTD

Searching record display method and electronic device

The present invention relates to the field of the Internet and discloses a searching record display method and an electronic device so as to solve the technical problem that in prior art, when searching is carried out based on a search engine, the valid data amount obtained by a first screen is relatively small. The method comprises: receiving a search operation of carrying out network searching by a user through key information; then responding to the search operation to obtain a first search result under a first search engine; displaying the first search result on a first display area of a display interface of a browser, and displaying a second search result on a second display area of the display interface; determining whether a display width of the display interface is greater than a predetermined width; and when the display width is not greater than the predetermined width, displaying the keyword information corresponding to at least one searching record in the first search result and/or the second search result. The method and the electronic device which are provided by the present invention achieve the technical effect of increasing the valid data amount obtained by the first screen when searching is carried out based on the search engine.
Owner:BEIJING QIHOO TECH CO LTD

Application of product for detecting ddcfDNA in preparing product for detecting transplanted kidney injuries caused by pulmonary infection and evaluating prognosis effect

The invention provides application of a product for detecting ddcfDNA in preparing a product for detecting transplanted kidney injuries caused by pulmonary infection and evaluating a prognosis effect,the product for detecting the transplanted kidney injuries caused by pulmonary infection and evaluating the prognosis effect, and a method for detecting the transplanted kidney injuries caused by pulmonary infection and evaluating the prognosis effect. The product for detecting the ddcfDNA can detect the level of the donor free cfDNA (ddcfDNA) in plasma of a kidney transplant recipient, accordingto the level of the donor free cfDNA (ddcfDNA), the transplanted kidney function injuries caused by pulmonary infection are diagnosed, the prognosis effect is evaluated, the early diagnosis of the transplanted kidney injures caused by pulmonary infection and the prognosis effect for the organ transplant recipient after an operation can be achieved, the product for detecting the ddcfDNA has the advantages of rapidity, accuracy and high sensitivity, the detection method is non-invasive, and the pain of the patient is greatly reduced.
Owner:上海奥根诊断技术有限公司

Concealed electricity stealing behavior identification method based on synthetic minority class oversampling technology

The invention discloses a hidden electricity stealing behavior identification method based on a synthetic minority class oversampling technology, and belongs to the field of power supply management. Collecting power consumption data of normal users and recorded abnormal users in a certain period of time; collecting weather temperature data of a corresponding time period; carrying out data expansion based on a minority class oversampling technology; carrying out user feature data label construction; carrying out random forest algorithm electricity stealing behavior prediction; and judging or predicting whether a user finally has an electricity stealing behavior. According to the method, except for user power utilization characteristic indexes, weather factors and user power utilization time-space correlation are considered, the hidden characteristic of power stealing behaviors is considered, abnormal samples with small sample sizes are expanded by using a synthetic minority class oversampling technology, the effective data size and coverage range of the samples are improved, the model training precision is improved, and the model training efficiency is improved. And the identification capability of the electricity stealing behavior is enhanced.
Owner:SHANGHAI MUNICIPAL ELECTRIC POWER CO

High-throughput sequencing database construction technology capable of efficiently capturing three-dimensional conformation of chromosomes of frozen biological sample

The invention discloses a high-throughput sequencing database construction technology capable of efficiently capturing the three-dimensional conformation of chromosomes of a frozen biological sample.The invention provides a sample pre-processing method suitable for Hi-C high-throughput sequencing library building. The sample pre-processing method includes the steps of freezing a biological sampleto be tested first, then increasing the temperature in a gradient mode, and then cross-linking and fixing. The FS-Hi-C technology is not only suitable for fresh samples, but also for frozen samples.The results show that the three-dimensional structure of chromatin of a frozen replacement sample and a fresh sample are highly similar, and the quality of a Hi-C library is improved. Compared with atraditional Hi-C pretreatment method, FS-Hi-C is highly consistent in chromatin interaction, A / B compartment and TAD and the like, the quality of the library constructed by the FS-Hi-C method is better, the storage capacity is increased, effective interaction data is more, and the repeated data generated by PCR amplification is reduced. The technology reduces the requirements for sample timeliness. The high-throughput sequencing database construction technology provides an improved method for the application of Hi-C in biology.
Owner:INST OF COTTON RES CHINESE ACAD OF AGRI SCI

Plasma free dna bimolecular labeling, method for labeling and detecting plasma cfdna and its application

The invention provides a plasma cfDNA (cell-free deoxyribonucleic acid) bi-molecular marker. The bi-molecular marker is oligonucleotide, the sequence is represented as follows: a) 5'P-GACGTC-GATCGGAAGAGCTCGTATGCCGTCTTCTGCTTG, b) 5' ACACTCTTTCCCTACACGACGCTCTTCCGATCT-NNNNNNNNNNNNNNNNNNNN-GACGTCT, the sequence of oligonucleotide is from the 5' terminal to the 3' terminal from left to right, N represents a random basic group, and P represents a phosphate group; the oligonucleotide sequence is synthesized artificially. The plasma cfDNA bi-molecular marker is used for distinguishing every plasma cfDNA molecule by adding a unique molecular marker to every plasma cfDNA molecule and can be applied to plasma cfDNA detection. The plasma cfDNA bi-molecular marker overcomes defects of cfDNA detection with a conventional NGS (next generation sequencing) technology, and specifically has following technical effects: 1), the cfDNA valid data volume in a database construction process is increased; 2), noise signals such as deviation and detection errors produced in intermediate steps of gene detection can be reduced; 3), target variation can be effectively detected, meanwhile, low false positive rate is realized, and accuracy and stability of gene detection are improved.
Owner:GUANGZHOU REFORGENE MEDICINE CO LTD

Method for selecting web page browsing mode and electronic device

The present invention relates to the field of the Internet, and discloses a webpage browsing mode selection method and an electronic device so as to solve the technical problem in the prior art of a relatively small volume of valid data acquired by a home screen during a search based on a search engine. The method comprises: receiving a search operation; responding to the search operation and searching by means of a first search engine to obtain a first search result, wherein the first search result comprises M pieces of promotion information; determining whether a display width of a display interface of a browser is greater than a preset width; when the display width is greater than the preset width, displaying the first search result in a first display region of the display interface, wherein the first search result comprises the M pieces of promotion information; and displaying a second search result in a second display region of the display interface, wherein promotion information contained in the second search result is a proper subset of the M pieces of promotion information. The technical effect of increasing the volume of the valid data acquired by the home screen during the search based on the search engine is achieved.
Owner:BEIJING QIHOO TECH CO LTD

A search record display method and electronic device

The present invention relates to the field of the Internet and discloses a searching record display method and an electronic device so as to solve the technical problem that in prior art, when searching is carried out based on a search engine, the valid data amount obtained by a first screen is relatively small. The method comprises: receiving a search operation of carrying out network searching by a user through key information; then responding to the search operation to obtain a first search result under a first search engine; displaying the first search result on a first display area of a display interface of a browser, and displaying a second search result on a second display area of the display interface; determining whether a display width of the display interface is greater than a predetermined width; and when the display width is not greater than the predetermined width, displaying the keyword information corresponding to at least one searching record in the first search result and / or the second search result. The method and the electronic device which are provided by the present invention achieve the technical effect of increasing the valid data amount obtained by the first screen when searching is carried out based on the search engine.
Owner:BEIJING QIHOO TECH CO LTD

Webpage browsing mode selection method and electronic device

The present invention relates to the field of the Internet, and discloses a webpage browsing mode selection method and an electronic device so as to solve the technical problem in the prior art of a relatively small volume of valid data acquired by a home screen during a search based on a search engine. The method comprises: receiving a search operation; responding to the search operation and searching by means of a first search engine to obtain a first search result, wherein the first search result comprises M pieces of promotion information; determining whether a display width of a display interface of a browser is greater than a preset width; when the display width is greater than the preset width, displaying the first search result in a first display region of the display interface, wherein the first search result comprises the M pieces of promotion information; and displaying a second search result in a second display region of the display interface, wherein promotion information contained in the second search result is a proper subset of the M pieces of promotion information. The technical effect of increasing the volume of the valid data acquired by the home screen during the search based on the search engine is achieved.
Owner:BEIJING QIHOO TECH CO LTD

Capture library and kit for detection of 50 tumor-associated hotspot mutation genes

The invention discloses a kit and a method for detecting 50 tumor-relevant hotspot mutation genes. According to the method, a capture method of 207 hotspot mutation regions of 50 relevant genes (including oncogenes and cancer suppressor genes) and a preparation method of a liquid-phase hybridization library used in capturing are researched aiming at oncology. The method particularly comprises the steps of selecting sequence information of 207 hotspot mutation regions, designing a PCR primer, preparing a biotin labeled liquid-phase hybridization library by virtue of a PCR method, hybridizing the biotin labeled liquid-phase hybridization library with a constructed target genome DNA library, and carrying out high-throughput sequencing and bioinformatics analysis on captured fragments, so as to obtain the mutation condition of nucleic acid sequence sites of a sample. By virtue of the method provided by the invention, high-quality sequencing data can be obtained, the relatively high capturing efficiency and the relatively good uniform capturing of the target sites can be realized, the disadvantages of low efficiency, poor uniformity and the like of solid phase hybridization are solved, and the sequencing cost is greatly lowered.
Owner:DALIAN GENTALKER BIO-TECH CO LTD

Evaluation Method of Hierarchical Diagnosis and Treatment Based on Data Mining

ActiveCN105893766BIncrease the amount of effective dataSolve the problem that business data cannot be directly usedMedical data miningHealthcare resources and facilitiesDiseasePaired Data
The invention discloses a hierarchical diagnosis and treatment evaluation method based on data mining. This method extracts basic patient information and diagnosis and treatment information from medical records, and associates them with disease type information and medical institution information, first cleans the data and fills in missing values, and classifies patients in different flow directions; then uses this data to calculate hierarchical diagnosis and treatment monitoring indicators; Through the GainRatioAttributeEva feature selection algorithm and the RIPPER classification algorithm, the behavior and characteristics of different patients are described. The present invention evaluates the graded diagnosis and treatment through qualitative indicators and quantitative indicators, and overcomes the shortcomings of the current graded diagnosis and treatment evaluation method that there are only quantitative indicators, the indicators need to be reported layer by layer, there are misreporting and random reports in the reporting process, and there is no reason behind the lack of tracking indicators. And use data mining technology to make graded diagnosis and treatment evaluation more timely and accurate.
Owner:CHENGDU SHULIAN YIKANG TECH CO LTD
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