The invention discloses a waterproof ink for packaging and printing and a preparation method thereof. The raw materials include: maleic resin, water-soluble 
acrylic resin, 
carboxymethyl cellulose, 
ethyl acetate, isopropanol, a stabilizer, a leveling agent, a 
defoamer, a dispersant, a waterproof agent, a slipping agent, pigments, 
xanthan gum, Arabic gum and fine pored 
silica gel. The specific stepsinclude: 1) mixing and heating maleic resin, water-soluble 
acrylic resin, 
carboxymethyl cellulose, 
ethyl acetate and isopropanol, and then performing stirring to obtain an 
emulsion; 2) heating the stabilizer, the leveling agent, the 
defoamer, the dispersant, the waterproof agent, the slipping agent and the pigments, then conducting 
ultrasonic vibration to obtain an auxiliary material; and 3) mixing 
xanthan gum, Arabic gum and fine pored 
silica gel, then adding the mixture into the 
emulsion, then adding the auxiliary material, performing high-speed stirring, and then conducting 
grinding. The ink prepared by the method provided by the invention has the advantages of simple process, low cost, good waterproofness, firm adhesion, etc., and has broad market prospects.