The invention provides a 4D breathable vamp which comprises a vamp body. The 4D breathable vamp is characterized in that the vamp body comprises a surface layer, a lining layer and a bottom layer which integrally adhered, the whole surface layer is made screen cloth, the density of the lining layer is larger than that of the surface layer and the bottom layer, the lining layer is made of knitted fabric with single-color or colorful printings, the surface, with the printings, of the lining layer faces the surface layer, the lining layer is 1.5-3mm in thickness and comprises a plurality of components, the lining layer are respectively adhered to the surface layer and the bottom layer, the whole bottom layer is made of sandwich screen cloth, and the sandwich screen cloth comprises an upper layer, a connecting layer and a lower layer. The invention further provides a shoe made by vamp body. The 4D breathable vamp has the advantages that vamp is light and breathable and has certain hardness, shoe shape can be kept, wearing comfortableness is achieved, the feet of a wearer are less prone to bruising, diversified decorating patterns can be designed on the vamp, a three-dimensional effect is achieved, vamp design freedom is achieved, and the vamp is convenient to produce and attractive in appearance.