The invention discloses a hot plug type middle-high voltage power distribution prefabricated cabin, which comprises a bus and outgoing line integrated fixed prefabricated cabin and a power distribution unit type movable prefabricated cabin, and is characterized in that the bus and outgoing line integrated fixed prefabricated cabin comprises a high voltage fixed cabin, a middle voltage fixed cabin and an interval inner cabin, a GIL bus, a GIS outlet cable sleeve, a bus and outlet static contact insulating sleeve are arranged in the cabin. The power distribution unit type mobile prefabricated cabin internally comprises GIS power distribution unit equipment, a lead, a bus and an outgoing line moving contact sleeve; hot plugging between the bus and outgoing line integrated fixed prefabricated cabin and the power distribution device unit type mobile prefabricated cabin is realized through a moving contact and a static contact, and the static contacts of the bus and outgoing line integrated fixed prefabricated cabin are compactly arranged in an electrified manner through an insulating sleeve. The invention aims to solve the problems that various devices and materials need to be purchased to be combined and matched from drawings to engineering sites due to the fact that an existing middle-high voltage power distribution device needs to be designed, manufactured, constructed and debugged in various installation stages, construction and installation are time-consuming and labor-consuming, power-off overhaul is difficult, and operation and maintenance are not changed. The design, manufacture, installation, operation and maintenance modes of the current middle and high voltage power distribution device are thoroughly changed, and the device has the advantages of compact structure, small occupied area, convenience in design, construction, operation and maintenance, short power failure time, basically no on-site electrical operation and the like.