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302 results about "Duodenum/Duodenal" patented technology

Device and Method for Treating Weight Disorders

An apparatus and a method for treating a weight disorder in a subject are provided. The apparatus comprising an implantable device such as an inflatable balloon and electrodes capable of sensing a physiological change associated with food ingestion or hunger and a mechanism adapted for directly stimulating a region such as the duodenum which is responsive to a gastrointestinal satiety agent, such a mechanism can be a drug reservoir containing a drug such as CCK or analogs thereof which is contained within an inflatable balloon being implantable in a stomach of the subject. The apparatus and method provided here combine synergistic approaches to limiting meal size, i.e., chemo and mechano receptor activation of vagal satiety stimuli, electric stimulation of specific vagal pathways and limitations of gastric space.
Owner:DUOCURE

Health-care flour composition and food

The invention provides a health-care flour composition and food and a preparing method thereof. According to the preparing method, hericium erinaceus and flour are used as main raw materials, swelling agents, sweetening agents, oil, salt and the like are added and mixed with water, and then rolling, forming, baking, oil injection and cooling are carried out to obtain various foods made of flour or pastries such as cookies, cakes and noodles. The health-care flour composition and food are even in texture, capable of being stored for a long time easily, good in mouthfeel and rich in nutrient, and market vacancy is filled. The health-care flour composition and food have definite effects in repairing gastric mucosal damage caused by chronic gastritis, or gastric ulcers or duodenal ulcers, relieving abdominal pains caused by chronic gastritis, or gastric ulcers or duodenal ulcers, inhibiting helicobacter pylori, and assisting the treatment of chronic gastritis, gastric ulcers and duodenal ulcers.
Owner:江中食疗科技有限公司

Method and compositions for the treatment of gastrointestinal disorders

Compositions and related methods for treating IBS and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia (including functional dyspepsia or nonulcer dyspepsia), gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudoobstruction), and disorders and conditions associated with constipation, e.g., constipation associated with use of opiate pain killers, post-surgical constipation, and constipation associated with neuropathic disorders as well as other conditions and disorders are described. The compositions feature peptides that activate the guanylate cyclase C (GC-C) receptor.
Owner:IRONWOOD PHARMA

Methods and compositions for the treatment of gastrointestinal disorders

Compositions and related methods for treating IBS and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia (including functional dyspepsia or nonulcer dyspepsia), gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudoobstruction), and disorders and conditions associated with constipation, e.g., constipation associated with use of opiate pain killers, post-surgical constipation, and constipation associated with neuropathic disorders as well as other conditions and disorders are described. The compositions feature peptides that activate the guanylate cyclase C (GC-C) receptor.
Owner:IRONWOOD PHARMA

Novel compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and pharmaceutical compositions containing the same

This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receotor 1; VR1; TRPV1 )antagonist; and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treating a disease such as pain, migraine, arthralgia, neuralgia, neuropathies, nerve injury, skin disorder, urinary bladder hypersensitiveness, irritable bowel syndrome, fecal urgency, a respiratory disorder, irritation of skin, eye or mucous membrane, stomach-duodenal ulcer, inflammatory diseases, ear disease, and heart disease.
Owner:AMOREPACIFIC CORP

Lactobacillus reuteri and its application

The invention relates to the technical field of microorganism, and discloses a Lactobacillus reuteri and its application. The preservation number of the Lactobacillus reuteri CCFM8631 is CGMCC No.14394; the level of mice peripheral neurotransmitter 5-hydroxytryptamine can be significantlyimproved; the rise of the mice peripheral blood testonsterone level and the abundant abnormity of Blautia, Turicibacter, Oscillospira and Bifidobacterium in the intestinal flora by high glucose and high fatty diets are recovered; the tolerated simulative gastrointestinal fluid is rapidly planted in an intestinal tract, so as to significantly improve the pathological injury of metabolic syndrome mice liver and duodenum and rise of triglyceride and total cholesterol content in the serum by high glucose and high fatty diets are significantly improved; the Lactobacillus reuteri can be used for preventing, delaying or treating metabolic disorder such as metabolic syndrome, irritable bowel syndrome, and anxiety, depression and other metal diseases related to irritable bowel syndrome.
Owner:INFINITUS (CHINA) CO LTD

Duodenal sleeve and conveyor thereof

The invention provides a duodenal sleeve which is composed of a metal framework and an outer sleeve coated outside the metal framework. The metal framework is of a spiral ring structure and divided into a duodenal spherical cavity section for the metal framework and a duodenal spherical rear section for the metal framework; the spiral ring of the duodenal spherical cavity section for the metal framework is bigger and denser than that of the duodenal spherical rear section for the metal framework; the spiral ring structure of the duodenal spherical cavity section for the metal framework is in a bowl or funnel shape; the top and the bottom of the metal framework are equipped with circular or oval annular closed opening; and the outer sleeve is coated outside the metal framework and the lower end thereof is longer than the bottom end of the metal framework. The invention further provides a conveyor for the duodenal sleeve, comprising a plastic hose, wherein, longitudinal cracks are arranged on the wall of the plastic hose from the head end to the tail end thereof. The duodenal sleeve is used for transporting stomach effluents from a stomach pylorus, replaces gastric bypass operation, avoids that the stomach effluents are directly digested, absorbed and metabolized in duodenum, and treats adiposis and diabetes.
Owner:南京速能医疗器械设计有限公司

Inner coverage membrane for duodenum

ActiveCN103142262AAvoid damageAvoid incarcerationSurgeryStomachHuman bodyDiabetes mellitus
The invention provides an inner coverage membrane for duodenum. The inner coverage membrane is obtained from biocompatibility materials, and is formed by an elastic kettle belly part and a tubular part, wherein the kettle belly part is arranged in a sphere part of the duodenum, the tubular part can be extended to jejunum, the kettle belly part comprises a wave-shaped, a V-shaped, a ladder-shaped or a wall-shaped elastic circle which is continuously wound, the elastic circle is made of memorized or non-memorized biocompatibility materials, a peak, a valley and a curved angle of the elastic circle are single-circled bending springs and are with an outward anchor and hook, a retrieve thread is wound on the single-circled bending spring on the lower edge in a penetrating manner, the upper edge of the kettle belly part is a wave-shaped, a V-shaped, ladder-shaped or a wall-shaped elastic membrane, the elastic circle and the overall kettle belly part move along with the duodenum and the sphere part, and the kettle belly part and the tubular part can be closed or folded into a sphere shape, a cylindrical shape, a capsule shape or a spindle shape outside a human body. The single-circled bending springs have the advantages of strong elasticity, weak sharp injury, excellent fixing performance for the retrieve thread attached on the single-circled bending spring, and benefit for an anatomized structure and basic physiologic functions of the duodenum. The inner coverage membrane for duodenum can be prepared into a medical appliance for preventing and curing obesity and diabetes.
Owner:万平

Sheathed Duodenoscope

A sheathed endoscope, includes: an endoscope and a disposable component. The disposable compartment protects the inner and outer surfaces of the endoscope. The disposable compartment includes: a cap of endoscope tip in the distal end of endoscope, a disposable tube for biopsy forceps, and an outside sheath capsule for endoscope shaft. The tip cap connects the sheath capsule and the disposable tube for biopsy forceps. There are multiple windows set on the lateral side of endoscope tip, wherein pills containing transparent fluid are placed somewhere in between of the tip cap and the distal end of endoscope. The pills will be crushed by co-fraction of the tip cap and the distal end of endoscope, to release the transparent fluid to fill in the space formed between the tip cap and the distal end of the endoscope. This disposable sheath compartment in the invention will cover all surfaces of the endoscope with disposable material, preventing contaminations on endoscope during endoscopy, meanwhile there is anti-glaring design, to prevent producing of glaring in the space formed between the tip cap and the distal end of endoscope.
Owner:SHENYANG SHENDA ENDOSCOPE

Rhodiola rosea compound composition for treating peptic ulcer

The invention discloses a rhodiola rosea compound composition for treating peptic ulcer. The rhodiola rosea compound composition is a preparation prepared from the following active pharmaceutical ingredients in parts by weight: 4.2-7.2 parts of rhodiola rosea, 14-26 parts of poria cocos, 10.5-19.5 parts of dandelion, 10.5-19.5 parts of capillary artemisia, 10.5-19.5 parts of white atractylodes rhizome, 7-13 parts of pogostemon cablin, 7-13 parts of raw malt, and 3.5-6.5 parts of fructus amomi rotundus. The compound composition disclosed by the invention is exact in compatibility of medicines, quite less in medical ingredients, not only capable of ensuring medicine efficacy and reducing side effects, but also capable of effectively treating gastric ulcer, duodenal ulcer, and erosive gastritis, and provides a new administration choice for the clinical treatment of the peptic ulcer.
Owner:CHINA ACAD OF SCI NORTHWEST HIGHLAND BIOLOGY INST

Medical equipment and application thereof

The invention relates to the field of medical equipment and application thereof, and provides a duodenum internal covering film. The duodenum internal covering film is made of biocompatible biodegradable or non-biodegradable material or / and hydrophobic material and is mainly composed of an elastic ampullar portion and a tubular portion. The ampullar portion comprises a biocompatible bionic micro array adhesion piece which can achieve strong adhesion in the force application direction, does not stab intestine tissues and is capable of achieving detachment and recovery easily. The adhesion piece is good in stability, strong in adaptability to material and shapes, good in self-cleaning performance, free of damage and pollution to the intestine tissues, and capable of achieving repeated adhesion and detachment and supporting other components mutually in functions. When intestinal tract contents move, the internal covering film can not be detached due to the fact that subvertical pulling force does not exist. When the duodenum bulb is expanded and inflated, the internal covering film can not be detached due to the fact that the internal covering film does not have opposite and subvertical pulling force, and in the process of recovery, the internal covering film can be detached and recovered easily through force applied in a subvertical mode. The duodenum internal covering film can be manufactured into the medical equipment which does not damage the intestine tissues and can prevent and cure fat and diabetes.
Owner:万平

Esomeprazole magnesium sustained-release dropping pill and preparation method thereof

The invention discloses a pharmaceutical preparation used for treating erosive reflux oesophagitis, a gastroesophageal reflux disease, maintaining a long-term therapy to prevent the recurrence of oesophagitis for a cured patient, controlling the symptoms of gastroesophageal reflux diseases, eradicating helicobacter pylori jointly medicated with an appropriate antimicrobial therapy, healing duodenal ulcer related to helicobacter pylori infections and preventing the recurrence of peptic ulcer related to helicobacter pylori, and particularly relates to a prepared sustained-release oral formulation adopting esomeprazole magnesium as the ingredient. The pharmaceutical preparation aims to supplement the deficiency of the prior art and provide a sustained-release esomeprazole magnesium dropping pill. The sustained-release esomeprazole magnesium dropping pill overcomes the defects in the prior art effectively, guarantees no occurrence of an obvious quality change for the drug during the effective storage period and has the advantages of controllable release time, full release and high bioavailability simultaneously.
Owner:北京博智绿洲医药科技有限公司

A real-time auxiliary diagnosis system and method for endoscopic retrograde pancreatic duct radiography

The invention discloses a real-time auxiliary diagnosis system and method for endoscopic retrograde pancreatic duct radiography. The system comprises a client, a server and a database, An ERCP image is collected through a client side, the obtained ERCP image is input into a trained deep learning model to be recognized and classified, and corresponding image information (including duodenal papillaand papilla opening recognition and disease diagnosis) is obtained and fed back to the client side in time. A doctor can be helped to determine the duodenal papilla and the papilla opening position, and the intubation success rate is increased; In addition, doctors can be assisted to diagnose diseases, misdiagnosis and missed diagnosis are prevented, and the diagnosis accuracy and the working efficiency are improved.
Owner:武汉大学人民医院

Dietetic therapy meal auxiliary or meal replacement product for gastric ulcer and duodenal ulcer

The invention relates to a dietetic therapy meal auxiliary or meal replacement product for gastric ulcer and duodenal ulcer. The main components and a preparation method are as below: first conducting superfine grinding on chicken's gizzard membrane, cape jasmine, a honeysuckle decoction, a kiwi fruit powder, pine pollen, a fingered citron powder, lily, processed licorice, clove and litchi into a powder, and adding a coix seed powder, a Poria powder, a wheat germ powder, a Chinese yam powder and a walnut powder; or decocting the materials with water, filtering the decoction and spraying a filtrate into the coix seed powder, the Poria powder, the wheat germ powder, the Chinese yam powder and the walnut powder; conducting high temperature slaking on the mixture; adding xylo oligosaccharide, a Lactobacillus acidophilus powder, a bifidobacterium powder, a natto powder, a yeast powder, an L-arabinose powder and a spirulina powder; mixing uniformly; and conducting subpackaging. The invention employs reasonable compatibility of materials which are used as both food and medicine and utilizes the principle of balance constitution in traditional Chinese medicine, so that the human body can restore balance and achieve the stable state of health through diet. The product reduces incidence of diseases related to gastric ulcer and duodenal ulcer physique and has the advanategs of safety, effectiveness, little toxic or side effect, common food as the main raw materials, low price and easiness for people to accept.
Owner:浙江永葆康安医疗科技有限公司

Medicine composition for treating gastritis, and its prepn. method

A Chinese medicine for treating gastritis, acute or chronic gastritis, duodenal bulbar inflammation, gastric ulcer, duodenal ulcer, etc is prepared from 16 Chinese-medicinal materials including dandelion herb, lily bulb, white peony root, tangerine peel, etc. Its preparing process is also disclosed.
Owner:张学军

Bifidobacterium adolescentis and use thereof

InactiveUS20190112674A1Improve their levelRelieve hyperglycemiaMilk preparationBacteriaBifidobacterium adolescentisDisease
Provided is a strain CCFM8630 of Bifidobacterium adolescentis and use thereof. The strain CCFM8630 of Bifidobacterium adolescentis can significantly increase neurotransmitter 5-hydroxytryptamine level in peripheral blood of rat, recover the hormone levels, for example testosterone and so on in peripheral blood of rat, normalize abnormal abundances of Bifidobacterium genus, Blautia genus and Turicibacter genus in intestinal flora of rat affected by high-fat high-starch diet, show pretty good tolerance to simulated gastrointestinal fluid and quickly colonize in intestinal, significantly improve pathological damages of tissues such as liver, duodenum and so on, and increase triglyceride and total cholesterol levels in serum and oral glucose tolerance of rat with metabolic syndrome caused by high-fat high-starch diet. The strain CCFM8630 of Bifidobacterium adolescentis can be used for preventing, relieving or treating metabolic disorder, such as metabolic syndrome, irritable bowel syndrome and mental diseases related to metabolic syndrome such as anxiety, depression and so on.
Owner:INFINITUS (CHINA) CO LTD

Methods for treating inflammation, autoimmune disorders and pain

Methods of treating, reducing, or preventing a disease or symptom relating to a disease such as oral mucositis, gingivitis, periodontitis, gastric mucositis, inflammatory fibrosis, gastritis, colitis, ileitis, Crohn's disease, chronic inflammatory intestinal disease, inflammatory bowel syndrome, chronic inflammatory bowel disease, celiac disease, ulcerative colitis, a gastric ulcer, a peptic ulcer, a buccal ulcer, a nasopharyngeal ulcer, an esophageal ulcer, a duodenal ulcer, a gastrointestinal ulcer, an autoimmune disorder, inflammation associated with cancer, cancer treatment, or radiation, and / or pain that include: identifying a patient in need of treatment; and administering a therapeutically effective amount of at least one cationic steroid antimicrobial (CSA), or a pharmaceutically acceptable salt thereof. Kits comprising such compositions and instructions on such methods are also contemplated herein.
Owner:BRIGHAM YOUNG UNIV

Traditional Chinese medicine composition for treating ulcer of stomach and duodenum, and method of preparing the same

InactiveCN101130013AAvoid damageReduce the number of writhing reactionsDigestive systemPill deliveryEvodia rutaecarpaHard Capsule
The invention relates to Chinese medicinal compositions for treating gastric ulcer, duodenal ulcer and process for preparation, which is prepared from corydalis tuber, banksia rose, evodia rutaecarpa, dried ginger, dried orange peel, cyperus tuber, toosendan fruit, root of herbaceous peony, honey-fried licorice root, blood clam shell, rice sprout and germinated barley. The dose forms of the medicament include granules, hard capsules, soft capsules, tablets, dripping pills, pills and oral liquid preparations.
Owner:米养素

Systems and Mehtods for Treating Obesity and Type 2 Diabetes

The present invention provides systems and methods for treating wounds in patients who lack the innate ability to regulate glucose (e.g., diabetic patients). In one aspect of the invention, a method includes positioning an internal bypass device within the duodenum to inhibit contact between chyme passing therethrough and an internal wall of the duodenum and maintaining the internal bypass device within the duodenum for a sufficient period of time to decrease insulin resistance and reduce a blood glucose level in the patient. The internal bypass device increases peripheral blood flow and elevates an immune system response to accelerate healing of the wound.
Owner:E2 LLC DENTONS

Chinese medicinal composition for treating gastropathy and method of preparing the same

The invention relates to a traditional Chinese medicine combination for curing gastric diseases and a preparation method thereof, which solve the problem that the original traditional Chinese combinations for curing gastric diseases do not have prominent effects and have high recurrence rate. The medicine combination is prepared by corydalis tuber, Chinaberry fruit, turmeric root tuber, evodia rutaecarpa, coptis chinensis, villous amomum fruit, costus root, radix linderae, rhizoma cyperi, frankincense, myrrh and cuttlebone. The traditional Chinese medicine combination has the functions of soothing the liver and regulating vital energy, removing heat from the liver, promoting blood circulation to arrest pain, promoting wound healing and granulation, and can be used for curing gastric and duodenal ulcer, gastritis, stomachache, salivation and sour regurgitation, nausea, retching, epigastric distension and depression; besides, the traditional Chinese combination has special curative effects on gastric ulcer and duodenal ulcer and has inhibiting effect on helicobacter pylori.
Owner:四川抗菌素工业研究所有限公司

Customized alimentary canal support and moulding method and application method thereof

The invention discloses a customized alimentary canal support and a moulding method and an application method thereof. The moulding method comprises the steps of building a three-dimensional model of an alimentary canal structure of an individual object, and the alimentary canal structure comprises an alimentary canal stenosis or an obstruction part; performing data analysis and structure adjusting to the three-dimensional model; designing a virtual support by using a software; manufacturing a die corresponding to the inner contour of the support; and braiding a customized alimentary canal support on the die. The application method comprises the steps of delivering the customized support that has 4-6 different signs to a position to be planted. The support is successfully installed when the signs arrive at the designed installation position and the rotation angle under the monitor of an X-ray flat detector. In the complex alimentary canal obstruction areas like turnovers of stomach-duodenum and intestine-intestine, a traditional support fails easily, and the support provided by the invention can be used for a best treatment effect because of having the advantages like non-symmetry, high dissect precision, low internal stress, and difficult rotation shedding.
Owner:BEIJING FRIENDSHIP HOSPITAL CAPITAL MEDICAL UNIV +1

Novel compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist

This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRPV1 )antagonist; and a pharmaceuticalcomposition containing the same. The present invention provides a pharmaceutical composition for preventing or treating a disease such as pain, migraine, arthralgia, neuralgia, neuropathies, nerve injury, skin disorder, urinary bladder hypersensitiveness, irritable bowel syndrome, fecal urgency, a respiratory disorder, irritation of skin, eye or mucous membrane, stomach-duodenal ulcer, inflammatory diseases, ear disease, heart disease and so on.
Owner:AMOREPACIFIC CORP

Medicine composition for treating stomach disease, its preparation method and use

The invention discloses a medicine compound for curing tummy bug, which including following ingredients and proportion: bismuth aluminic acid 100-300 shares, heavy magnesium carbonate 100-600 shares, sodium bicarbonate 100-400 shares, liquorice extractive powder 100-500 shares, frank mouse lippich 1-50 shares, fennel powder 1-50 shares, aloe powder 1-50 shares or / and grassleaved sweetflag rhizome 1-50 shares. It also discloses the manufacturing method for the medicine, the compound medicine is one compound preparation resisting acid and protecting gastric mucosa, it can be applied to cure stomach and duodenum abscess, chronic superficial gastritis, overmuch stomach acid, and nerve indigestion and so on.
Owner:HONGMEI PHARMA CHINA

Composition and preparation method thereof

InactiveCN107518383AReduce ulcer indexUlcer Index InhibitionDigestive systemBird material medical ingredientsDuodenal ulcerSpleen
The invention provides a composition. The composition is characterized by being prepared from the following ingredients in parts by weight: ginseng roots 1-15, poria cocos 3-25, Chinese yam 5-50, lotus seeds 2-25, coix seeds 3-50, white hyacinth beans 3-25, polished round-grained rice 20-400 or / and oats 20-400. The invention also relates to the application of the composition in health care food or medicines or products having functions of preventing and treating gastric mucosal damage caused by chronic gastritis, gastric ulcer or duodenal ulcer, relieving abdominal pain caused by the chronic gastritis or peptic ulcer and preventing and treating the syndrome of weakness of the spleen and the stomach.
Owner:江中食疗科技有限公司

Pancreas ultrasonic endoscopy navigation method and system based on artificial intelligence

The invention provides a pancreas ultrasonic endoscopy navigation method based on artificial intelligence. The pancreas ultrasonic endoscopy navigation method comprises the following steps: acquiringa pancreas ultrasonic endoscopy image; screening qualified pancreatic ultrasonic endoscopic images; performing site identification on the screened qualified images by using a pre-trained artificial intelligence network classification model; generating a guide line containing all stations in advance, displaying the stations and operation instructions of the corresponding stations on the guide lineaccording to the identified stations, and prompting the next endoscope operation, wherein the operation instructions are preset station operation instructions in one-to-one correspondence with different stations, and the guide line specifically comprises a gastral cavity line, a gastral cavity line, a duodenum ball line and a duodenum descending line. Endoscope doctors, especially beginners, can be well helped to ensure pancreas full coverage during pancreas ultrasonic endoscopy, a training system is perfected, and the training quality is improved.
Owner:WUHAN UNIV
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