The invention provides a
mental disease analysis device and equipment. ROI is divided for a tested whole brain, ROI
centroid coordinates and a BOLD
time sequence are obtained, fMRI data are processed through a sliding window method, correlation between ROIs in a time window is calculated, a time-resolved FC matrix is obtained, DTI data are processed through a probability tracking method, an SC matrix is obtained, and the SC matrix is used for analyzing mental diseases. An
Euclidean distance matrix is obtained based on ROI
centroid coordinates, a plurality of structure index matrixes are obtained based on an SC matrix, an edge pair
feature matrix is constructed based on the matrixes, each element corresponds to a pair of ROIs, PCA is executed on the edge pair
feature matrix, a PCA result is mapped back to the ROI pairs, a secondary edge pair
feature matrix is obtained, and the secondary edge pair feature matrix is obtained based on multiple
linear regression. According to the method, the predictive capacity from the
secondary side to the feature matrix to the FC matrix is estimated, a dynamic
structure function coupling time sequence matrix of each tested object is obtained,
mental disease analysis can be performed based on the matrix, the dynamic change characteristic of function connection along with time is fully considered, and
brain network abnormity related to mental diseases can be comprehensively evaluated.