The invention discloses a wheelchair provided with an active positioning device. The wheelchair comprises a frame and a drive device arranged on the bottom of the frame, wherein a spring cushion is arranged at the lower part of the frame, a storage board is arranged on the bottom of the frame, and the active positioning device is arranged at a backrest of the frame. For the wheelchair, the arranged active positioning device can receive the positioning information of the Beidou satellite in real time, then, through a GSM communication device, the positioning information is transmitted to the GSM terminal of a family member or a nursing attendant in real time, so that the phenomenon that the user gets lost is prevented; through a heart rate sensor arranged on an armrest, the probable heart rate value is provided for the user in real time, so that the user can conveniently adjust the activity state, and further, the normal heart rate value is achieved.