Provided is an intelligent respirator and aerating method of using the respirator, belonging to the technical field of medical instruments. The intelligent respirator comprises a circuit, an air channel, an operation panel, and a display; a flow meter and a transducer are installed inside the air channel; a power supply board is installed inside the circuit; the circuit further comprises a microcomputer electronic control panel and a vital sign transducer; the microcomputer electronic control panel is installed inside the circuit; the microcomputer electronic control panel is in communication connection respectively with the power supply board, the operation panel, the display, the air channel and the vital sign transducer. The aerating method of using the intelligent respirator comprises the following steps: collecting, by the microcomputer electronic control panel via the vital sign transducer, information changes of vital sign parameters, controlling the velocity ratio of air and oxygen in the air channel, and controlling a warning device, thereby achieving the intelligent adjustment to the oxygen concentration of the patient and sending out an alarm for emergency treatments. The intelligent respirator and aerating method of using the respirator can achieve the intelligent control, thus achieving the adjustment of oxygen concentration as in need and in time without changing the tidal volume.