The invention provides a complex product operation, maintenance and manufacturing integrated general model based on digital twinning. The complex product operation, maintenance and manufacturing integrated general model comprises an operation and maintenance system module, a virtual maintenance unit module, a maintenance center module, a manufacturing plant module and a data platform module. The invention also provides a digital twinning-based operation, maintenance and manufacturing integrated process operation mode, modeling simulation, data fusion processing and other solutions, and discusses digital twinning-based key technologies such as intelligent diagnosis, fault prediction, data comprehensive perception, knowledge base/instance library construction and the like. Complex product operation and maintenance and manufacturing information are deeply fused, operation and maintenance and manufacturing data are interactively fed back, virtual and real combination of complex product operation and maintenance and manufacturing is realized through digital twinning, and more real-time, efficient and intelligent integrated services are provided. According to the operation mode of the complex product operation, maintenance and manufacturing model based on digital twinning, deep integration of the complex product operation, maintenance and manufacturing process is achieved, and the information island phenomenon generated in the operation, maintenance and manufacturing links is eliminated.