The invention discloses an SOD (Superoxide Dismutase) solid beverage capable of adjusting the human body balance. The SOD solid beverage is prepared from the following raw materials: L-lysine hydrochloride, glycine, glutamine, sodium bicarbonate, citric acid, glucose, isomaltitol, sucrose, xylitol, a wetting agent, gingko fruits, sea buckthorns, hawthorn fruits, Chinese yams, corn peptide, soybeanpeptide, wheat oligopeptides, SOD extract and deep-sea fish collagen peptide. The invention further discloses a preparation method of the SOD solid beverage. The SOD solid beverage prepared by the invention has a good adjustment effect on physiological activity balance of human bodies; the SOD extract obtained by taking okras as raw materials and extracting is adopted, and other chemical components which easily have a side effect on the human bodies are not adopted, so that the SOD solid beverage is safe and healthy; the gingko fruits, the hawthorn fruits, the Chinese yams and the sea buckthorns are mutually matched, so that the SOD solid beverage can be used for effectively improving the improvement effect on deficiency of liver and kidney and stomach diseases, and has a very good kidneytonifying effect; and the SOD solid beverage can meet requirements of different users and has a wide market prospect.