The invention relates to an intelligent mobile phone wireless charging device for safe and reliable charging. The intelligent mobile phone wireless charging device comprises a main body, a protecting mechanism and two supporting mechanisms, wherein the protecting mechanism comprises a protecting unit and two telescopic units, and each telescopic unit comprises an air pump, an air pipe, an air cylinder, a piston, a connecting rod and two articulated units; each supporting mechanism comprises two supporting units; each supporting unit comprises a driving unit, a support rod, a supporting block, a second slip ring, a second limiting block and a fixed rod; and each driving unit comprises a driving motor, a buffer block, a driving shaft, a moving block and a first slip ring. According to the intelligent mobile phone wireless charging device for safe and reliable charging, the connecting rods are pulled through the telescopic units, so that a protection plate rotates, a mobile phone is covered with the protection plate, the mobile phone is effectively protected, and the charging is safe and reliable; and moreover, the position of the main body is raised through the supporting units, the main body is prevented from being stained with a water flow on a working table top to cause short circuit of an internal circuit and equipment damage, and then safe and reliable charging is further guaranteed.