The invention discloses a disperse dye thermosol dyeing method taking decamethylcyclopentasiloxane (D5) as a medium. The method comprises the following steps: (1) pretreating polyester fabric; (2) adding a certain amount of pure disperse dyes into a dyeing medium D5, controlling the amount of the dyeing medium D5, so that a ratio of the weight of a to-be-dyed fabric to the weight of the medium D5 is 1:10 to 1:30, dyeing in a dyeing machine, heating the system to 90-100 DEG C, preserving the temperature for 5-10 minutes, heating to the temperature of 180-200 DEG C, and performing thermosol fixation, wherein the fixation time is 10-30 minutes; and (3) performing reduction clearing on the dyed fabric according to a GB2394-80 method after dyeing. According to the method, non-aqueous medium dyeing is adopted, lots of water resources are saved, the thermosol temperature can be obtained under normal pressure, the conventional dyeing equipment can be adopted, the operation is simple, pure disperse dyes are adopted for dyeing, lots of dispersing aids are saved, the utilization rate of the dyes is improved, wastewater emission is reduced, and ecological environment protection is facilitated.