14 results about "Ligusticum striatum" patented technology

The invention provides a burn medicine formula and a preparation method thereof, and relates to the technical field of burn medicines, the burn medicine formula comprises a first component medicine and a second component medicine, the first component medicine comprises 45-50 parts of Eurya camara; 30 to 45 parts of platycarya strobilacea bark; 5-15 parts of rice skin; 5 to 15 parts of aloe; 5-15 parts of June cold; the second component medicine comprises tung catalpa or sesame. Eurya emarginata, platycarya strobilacea bark, rice peel, aloe, June herb and other components are mixed to prepare a first medicine, tung catalpa or sesame is squeezed to form a second medicine, the first medicine and the second medicine are uniformly stirred and mixed to be smeared to the wound of a patient in the use process, and all the components cooperate and promote each other, so that the effect of treating the wound is achieved. And the liquid medicine can quickly permeate into the deep layer of the skin, soften the skin, dredge nerves and blood vessels, prevent adhesion and inflammation, gradually soften the wounded part, achieve the effects of clearing away fire, promoting blood circulation, relieving pain, astringing, promoting granulation and accelerating normal growth of tender granulation, the recovery process is intact, and scars and lumps are not easy to remain.

This invention provides a dressing containing Ligusticum striatum microspheres and its preparation method, to solve the problem of safe and precise application of Ligusticum striatum extract or Ligustrazine in difficult-to-heal wounds; the dressing containing Ligusticum striatum microspheres and its preparation method, wherein the dressing is composed of Ligusticum striatum microspheres loaded with pHEMA hydrogel as the main body, wherein the Ligusticum striatum microspheres are formed by coating Ligusticum striatum extract or Ligustrazine with PLGA, and the pHEMA hydrogel partially encapsulates the Ligusticum striatum microspheres.

This invention discloses a topical traditional Chinese medicine composition for relieving pain and its preparation method, belonging to the field of traditional Chinese medicine preparation technology. The topical traditional Chinese medicine composition for relieving pain is made from the following raw materials in parts by weight: Angelica sinensis 5-25 parts, Ligusticum striatum 5-20 parts, Lycopodium clavatum 10-35 parts, Artemisia argyi 5-25 parts, artificial Phellodendron chinense 3-18 parts, Clematis chinensis 10-40 parts, and Angelica dahurica 5-20 parts. This invention uses steam distillation to extract volatile oils and a dual-solvent gradient extraction method with the residue, which not only fully extracts the volatile fat-soluble components from Angelica sinensis, Ligusticum striatum, and Angelica dahurica, but also efficiently extracts the water-soluble components from artificial Phellodendron chinense, Lycopodium clavatum, and other medicinal materials. Experimental results show that the extraction rates of ferulic acid, ligustilide, imperatorin, and berberine hydrochloride in Example 1 of this invention reached 89.23%, 92.56%, 90.12%, and 93.45%, respectively, which are 110.7%, 223.1%, 75.8%, and 23.6% higher than those of conventional water decoction process, thus improving the utilization rate of raw materials.

This invention discloses a method for preparing and applying a Miao medicine wine for treating bruises and sprains, comprising the following steps: S1, taking and mixing *Ligusticum striatum*, safflower, *Acanthopanax senticosus*, *Smilax china*, *Ligusticum chuanxiong*, *Sargentodoxa cuneata*, *Sargentodoxa cuneata*, and sappanwood evenly; S2, soaking the mixed Chinese medicinal materials from step S1 in alcohol to obtain the medicinal wine. This invention has the effects of clearing the meridians and relieving pain, promoting blood circulation and removing blood stasis, and promoting diuresis and reducing swelling. The treatment course is short, the efficacy is good, the cure rate is high, and recurrence is not common, with an effectiveness rate of over 98%. It has great potential for widespread application. Furthermore, the medicine of this invention is simple to manufacture, convenient to use, and has no toxic side effects, and can significantly alleviate patient suffering.

This invention provides a traditional Chinese medicine preparation for warming the meridians, dispelling cold, promoting blood circulation, and relieving pain, and its preparation method, relating to the field of traditional Chinese medicine pharmaceutical technology. The preparation is made from the following medicinal materials in parts by weight: 30-60 parts of *Banbianqi*, 20-50 parts of *Shancigu*, 30-60 parts of *Tianwencao*, 30-60 parts of *Zijingpi*, 30-60 parts of *Shufu*, 30-60 parts of *Shuitianqi*, 30-60 parts of *Shibazheng*, 30-60 parts of *Ligeng*, 30-60 parts of *Jiejiecha*, 30-60 parts of *Xuchangqing*, 30-60 parts of *Yunlanxiang*, 30-60 parts of *Baimu*, 30-60 parts of *Ligusticum striatum*, 20-50 parts of *Zhuifengsan*, 20-50 parts of *Shanhaitang*, 20-50 parts of *Dengzhanxixin*, and 20-50 parts of borneol. The formula is rationally combined, warming and invigorating blood circulation, and eliminating dampness and unblocking the meridians. Together, they achieve the effects of warming the meridians and unblocking the meridians, dispelling cold and dampness, promoting blood circulation and removing blood stasis, reducing swelling and relieving pain. The traditional Chinese medicine preparation of this invention has significant analgesic and analgesic effects, and can maintain the analgesic effect for a long time. At the same time, it has significant anti-inflammatory and swelling-reducing effects. When applied externally, it can directly reach the blocked meridians and joints to relieve symptoms such as pain, numbness, heaviness, and difficulty in flexion and extension of muscles, tendons and joints caused by cold and dampness obstruction.

This invention belongs to the field of biotechnology and discloses the application of plant-derived dehydrogenases or their encoding genes in the conversion of progesterone to 6-dehydroprogesterone. The plant-derived dehydrogenase is selected from the steroid 6-position dehydrogenase MtCYP79 derived from *Clematis chinensis* or the steroid 6-position dehydrogenase PsCYP79 derived from *Ligusticum striatum*. It also discloses a genetically engineered *Saccharomyces cerevisiae* strain that produces 6-dehydroprogesterone, which is based on a progesterone-producing *Saccharomyces cerevisiae* starting strain, into which the steroid 6-position dehydrogenase MtCYP79 or the steroid 6-position dehydrogenase PsCYP79 derived from *Ligusticum striatum* is introduced. The resulting genetically engineered *Saccharomyces cerevisiae* strain can produce both progesterone and 6-dehydroprogesterone.

The invention relates to the technical field of traditional Chinese medicine, and discloses a traditional Chinese medicine composition for promoting hair growth and a preparation method and application thereof.The traditional Chinese medicine composition is prepared from raw materials including notopterygium root, pawpaw, wine-processed ligusticum wallichii, angelica sinensis, prepared rehmannia root, prepared polygonum multiflorum, wine-processed glossy privet fruit, eclipta, mulberry, herba epimedii, gastrodia elata, barbary wolfberry fruit and Chinese yam according to a specific weight ratio. The preparation method comprises the following steps: preparing pills by using tender honey and honey water as adhesives by adopting a generic or plastic process, and carrying out covering treatment to obtain the traditional Chinese medicine honeyed pill preparation. The composition aims at the pathogenesis of liver and kidney deficiency and blood deficiency and wind dryness type alopecia, and through triple compatibility of nourishing liver and kidney to treat root causes, nourishing blood and activating blood to charge its source, and dispelling wind and dredging collaterals to open its way, the composition not only supplements the material basis of hair growth, but also improves the nutritional status of hair follicles and dredges stasis of hair orifices; the traditional Chinese medicine composition effectively solves the problems that an existing traditional Chinese medicine compound is tonified but not smooth, takes effect slowly, does not have an obvious curative effect on patients with wind pathogen or blood stasis syndromes and is high in relapse rate.

This invention provides a traditional Chinese medicine composition for treating or improving asthma, relating to the field of traditional Chinese medicine pharmaceutical technology. The composition comprises the following raw materials: Inula japonica, Bambusa textilis, Lysimachia christinae, Rutaecarpa, Ligusticum striatum, Pyrrosia lingua, Chaenomeles speciosa, Dioscorea hypoglauca, Atractylodes lancea, walnut kernel, maltose, Citronella arvense, and Glycyrrhiza uralensis. In this invention, each ingredient in the composition fulfills its specific function, addressing both the symptoms of asthma (phlegm and qi stagnation, and upward flow of lung qi) and the underlying causes (spleen strengthening, kidney tonification, and liver soothing). This achieves the combined effects of dispelling wind and clearing the lungs, resolving phlegm and descending rebellious qi, strengthening the spleen and resolving dampness, warming the kidneys and promoting qi circulation, and regulating liver qi. It treats both the symptoms and the root cause. This invention's composition effectively inhibits airway inflammation in asthma model mice, improves clinical symptoms, and demonstrates significant therapeutic effects. The composition exhibits a high overall effective rate in treating asthma, with particular advantages in alleviating clinical symptoms and improving lung function in asthma patients.

The invention discloses a herbal formula with the effects of regulating menstruation, relieving pain, warming ovary, warming uterus and dredging qi and blood, and particularly relates to the technical field of traditional Chinese medicine conditioning, and the herbal formula comprises special decoction prescriptions for the premenstrual period, the menstruation period and the post-menstrual period and corresponding preparation processes of the decoction prescriptions. The traditional Chinese medicine composition comprises the following components by weight: 5-7g of loofah sponge, 4-6g of liquidambar formosana hance, 5-7g of rose, 7-9g of fried hawthorn, 4-6g of pericarpium citri reticulatae, 9-11g of poria cocos and 20-30g of red dates. The formula strictly adapts to the physiological characteristics and common discomfort of the menstrual cycle including the premenstrual period, the menstrual period and the post-menstrual period, staged precise intervention is achieved, the limitation of a single soup formula is broken through, meanwhile, dual repair of ovary maintenance and qi and blood nourishing is achieved, and the curative effect is good. Periodic conditioning can effectively relieve common menstrual period problems such as premenstrual swelling pain, menstrual period abdominal pain and latter menstrual period weakness, and long-term use of the traditional Chinese medicine is helpful for improving the menstrual cycle rule, so that female reproductive health is maintained from the source.

The invention provides an external traditional Chinese medicine composition with a bacteriostatic effect and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine compositions. The traditional Chinese medicine composition comprises 20-40 parts of pepper, 20-40 parts of fructus cnidii, 10-30 parts of ligusticum, 5-15 parts of pogostemon cablin, 20-40 parts of schizonepeta, 10-30 parts of senecio scandens and 20-40 parts of mint. A response surface experiment design is adopted to optimize an extraction process of traditional Chinese medicinal materials and medicine residues, and the content of effective components such as total flavonoids in the extract is increased; the oil-soluble matrix and the water-soluble matrix are selected, so that the water-soluble medicine components and the oil-soluble medicine components can be better mixed, and the stability is high. The traditional Chinese medicine composition disclosed by the invention can inhibit the formation of bacterial cell membranes and destroy the structures of the bacterial cell membranes, and the permeability of the cell membranes is improved, so that macromolecular substances and proteins are leaked; the intracellular ATP content is reduced, and the extracellular alkaline phosphatase is increased, so that the growth of bacteria is finally inhibited or the bacteria are killed. According to the extraction process, effective components of the medicine are extracted to the maximum extent, and efficient utilization of the medicinal materials is guaranteed.

This invention belongs to the field of traditional Chinese medicine technology, specifically relating to a traditional Chinese medicine composition for treating neurodegenerative diseases and its preparation method. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 20-25 parts of Acorus tatarinowii, 18-23 parts of Rhizoma Cynoglossum, 15-20 parts of Cistanche deserticola, 9-13 parts of Herba Lysimachiae, 10-14 parts of Citrus medica, 7-12 parts of Semen Cuscutae, 5-10 parts of Radix Draconis, 7-13 parts of Radix Poriae, 8-12 parts of Flos Carthami, 6-10 parts of Twigs Cinnamomi, and 3-8 parts of Radix Glycyrrhizae. This invention is based on the principle of "principal, assistant, adjuvant, and guide" in traditional Chinese medicine formula. The principal herbs are Acorus tatarinowii, Rhizoma Citri Reticulatae, and Herba Cistanche deserticola, which invigorate the mind, refresh the spirit, and nourish the kidneys and essence. The assistant herbs are Ligusticum striatum, Semen Cuscutae, and Fructus Citri Reticulatae, which soothe the liver, regulate qi, and promote blood circulation. The adjuvant herbs are Dragon's Blood, Poria cocos, Twig of Cinnamomi Ramulus, and Flos Carthami, which resolve blood stasis, unblock meridians, calm the mind, and warm the yang and unblock the meridians. The guide herb is Glycyrrhiza uralensis, which harmonizes the effects of all the herbs. The entire formula is both nourishing and clearing, tonifying without causing stagnation, and the herbs work synergistically to achieve the goal of treating Alzheimer's disease.

The invention discloses a traditional Chinese medicine composition for treating arthralgia. The traditional Chinese medicine composition is prepared from honeysuckle stem, Chinese starjasmine stem, caulis sinomenii, kadsura pepper stem, tinospora sinensis merr, radix puerariae, cassia twig, angelica sinensis, radix paeoniae rubra, ligusticum wallichii, notopterygium root, radix angelicae pubescentis, peach kernel, safflower carthamus, radix clematidis, galangal, asarum, cinnamon leaf, radix cynanchi auriculati and radix zanthoxyli. Therefore, the invention further develops a traditional Chinese medicine preparation of the dredging ointment for treating arthralgia, and establishes a corresponding preparation method. According to the traditional Chinese medicine composition disclosed by the invention, the medicinal materials such as the five vines, the notopterygium root, the radix angelicae pubescentis, the peach kernel and the safflower are matched, so that a compound syndrome type of wind-cold-dampness-blood stasis and deep meridian blockage is accurately covered, and is not limited to mild wind-cold arthralgia or pure dampness arthralgia; the application mode of the incense applying method is flexible and convenient, the application position can be adjusted according to the affected part, and the incense applying device has adaptability to various severe arthralgia syndromes such as rheumatic arthritis. Meanwhile, the traditional Chinese medicine composition is simple in preparation process and convenient and safe to use, meets the requirement of long-term conditioning of patients with severe arthralgia syndromes, and overcomes the defects that in the prior art, the use threshold is high, and insistence at home is inconvenient.

This invention discloses a method for constructing a fingerprint spectrum of a traditional Chinese medicine composition containing Danshen and Astragalus. The method includes the following steps: taking a test solution and a reference solution of the traditional Chinese medicine composition for detection; obtaining the content information of the reference standard of the traditional Chinese medicine composition based on the detection results; wherein the traditional Chinese medicine composition includes Danshen, Polygonatum odoratum, Akebia trifoliata, Ligusticum striatum, Glycyrrhiza uralensis, Atractylodes macrocephala, Smilax glabra, Saposhnikovia divaricata, Rehmannia glutinosa, Ophiopogon japonicus, and Astragalus membranaceus; and the reference standard is caffeic acid, glycyrrhizin, rehmannia glutinosa D, cimicifugain, astilbin, salvianolic acid B, and ammonium glycyrrhizate. The detection method of this invention is simple, accurate, efficient, stable, precise, reproducible, convenient, and easy to master. It can effectively save energy and reduce analytical costs, while this technology is not disclosed in the prior art.

The invention discloses a Tibetan veterinary medicine composition for treating yak diarrhea as well as a preparation method and application thereof. The composition comprises Tibetan coptis chinensis, berberis poiretii schneid, fructus chebulae, dracocephalum tanguticum, polygonum viviparum, malus toringoides fruits, radix rubiae, scorched hawthorn fruits, fried malt, fructus hippophae, rhizoma zingiberis, rhizoma atractylodis, wine-treated rhubarb, oxytropis verticillata, fructus quisqualis, ligularia virgaurea, rhodiola rosea and saffron crocus. The Tibetan medicine composition provided by the invention strictly follows the principle of'three-cause balance 'of Tibetan medicine, is designed aiming at the common diseases of'red Ba' heat and'bai 'cold inclusion in plateau, and has the effects of clearing heat and drying dampness, detoxifying and stopping dysentery, tonifying spleen and warming middle-jiao, and simultaneously has multiple action mechanisms of plateau stress resistance, qi and blood regulation, parasite expelling and the like. The Tibetan medicine composition is safe and free of side effects, and can inhibit intestinal inflammation reaction, protect intestinal structure, promote nutrition digestion and absorption and enhance physique of yaks.