The invention provides an injectable
artificial bone matrix and a preparation method and application thereof.The method comprises the following steps that S1, a
whole blood sample is collected and centrifuged, and a
liquid plasma matrix on the upper layer, a
plasma matrix albuginea layer on the middle layer and a
red blood cell layer on the lower layer are obtained; s2, respectively collecting a
liquid plasma matrix and a
plasma matrix albuginea layer, heating the
liquid plasma matrix, and cooling to obtain
plasma matrix gel; s3, uniformly mixing the plasma matrix albuginea layer, the plasma matrix gel and the bone
repair material to obtain the injectable
artificial bone matrix. The liquid plasma matrix is heated and cooled to form the plasma matrix gel, and the plasma matrix gel is adopted to replace a conventional
solid plasma matrix to be mixed with the bone
repair material, so that the relative usage amount of the bone
repair material and the plasma matrix can be reduced, and the cost is reduced; meanwhile, the plasma matrix albuginea layer is added, a large number of enriched immune cells contained in the plasma matrix albuginea layer are utilized, the local
immune regulation function is achieved, and early-stage
wound healing can be accelerated.